Systems and methods for processing ultrasound color flow mapping

• US 9,173,640 B2
• Filed: 08/09/2013
• Issued: 11/03/2015
• Est. Priority Date: 08/09/2013
• Status: Active Grant

• Current Assignee: Sonowise, Inc.
• Original Assignee: Sonowise, Inc.
• Inventors: Lin, Shengtz
• Primary Examiner(s): Cwern, Jonathan
• Application Number:
  US13/963,509
• Publication Number:
  US 20150045666A1
• Time in Patent Office: 816 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/0891 for diagnosis of blood vessels
• CPC Class Codes: A61B 8/461 Displaying means of special interest
• CPC Class Codes: A61B 8/488 involving Doppler signals
• CPC Class Codes: A61B 8/5207 involving processing of raw data to produce diagnostic data, e.g. for generating an image reconstruction G06T11/00
• CPC Class Codes: A61B 8/5223 for extracting a diagnostic or physiological parameter from medical diagnostic data for algorithms to analyse biomedical images G06T7/0012
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

In one aspect, the invention relates to an ultrasound imaging system that includes an ultrasound receiver configured to receive ultrasound signals scattered from a sample in real time; an acoustic beam former; and an ultrasound data demodulation system. In one embodiment, the ultrasound imaging system further includes a processing system configured to process demodulated scan data and perform ultrasound image generation and flow processing and a display configured to show ultrasound image data and blood flow velocity data relative to such image data. Signals that include positive flow information and negative flow information are separated from received signals using phase-filters and analytic signal transforms such that a first and a second autocorrelation signal processing stage is used to generate mean positive flow, mean negative flow, and variance data for such flows.

Claims

1. A method of ultrasound color flow mapping comprising:

separating a positive flow signal and a negative flow signal from ultrasound data by transforming the ultrasound data using a first pair of Hilbert transforms and summing output signals from the pair of Hilbert transforms using one or more summers to generate a separated positive flow signal and a separated negative flow signal;

converting the separated positive flow signal and the separated negative flow signal into a positive flow analytic signal and a negative flow analytic signal using a second pair of Hilbert transforms;

autocorrelating the positive flow analytic signal to obtain a mean positive flow velocity;

autocorrelating the negative flow analytic signal to obtain a mean negative flow velocity; and

performing color flow mapping using the mean positive flow velocity and the mean negative flow velocity.

2. The method of claim 1 further comprising determining a flow velocity variance associated with the mean positive flow velocity or the mean negative flow velocity.

3. The method of claim 2 wherein performing color flow mapping further comprises using the flow velocity variance.

4. The method of claim 1 further comprising collecting the ultrasound data using a probe.

5. The method of claim 4 further comprising selecting a data acquisition period during which the ultrasound data is collected by the probe that ranges from about 2 milliseconds to about 32 milliseconds.

6. The method of claim 5 further comprising the step of selecting the data acquisition period to reduce occurrence of a spectral broadening artifact.

7. The method of claim 4 further comprising selecting a pulse repetition frequency in the range of from about 1 KHz to about 50 KHz for the probe.

8. The method of claim 1 further comprising performing the autocorrelation steps using the positive flow analytic signal and the negative flow analytic signal in the time domain.

9. The method of claim 1 further comprising

applying a first indicia to ultrasound image data corresponding to the mean positive flow;

and

applying a second indicia to ultrasound image data corresponding to the mean negative flow.

10. The method of claim 9 further comprising displaying the first indicia and the second indicia overlaid on a B-mode ultrasound image.

11. The method of claim 9 further comprising assigning a first color code for the mean positive flow, assigning a second color code for the mean negative flow, and assigning a third color code for the flow with both positive and negative flow.

12. The method of claim 1 wherein the ultrasound data comprises one or more RF signals and further comprising

wall filtering the one or more RF signals to remove vessel wall motion;

and

frequency shifting the positive flow analytic signal and the negative flow analytic signal using a mixer.

13. The method of claim 1 wherein a phase angle for one Hilbert transform of the first pair is set at about 0 degrees and a phase angle for the other Hilbert transform of the first pair is set at about 90 degrees.