Tracheobronchial implantable medical device and methods of use
First Claim
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1. An implantable medical device comprising:
- a bioabsorbable tracheobronchial stent adapted to be positioned in a tracheobronchial passageway from a throat to lungs of a mammal, wherein the tracheobronchial stent is operable to hold open the tracheobronchial passageway from the throat to the lungs, the tracheobronchial stent having a generally tubular body comprising a single coiled fiber, the generally tubular body having a proximal concentric end region, a middle concentric region, and a distal concentric end region, wherein the proximal and distal concentric end regions each have a greater pitch and a greater pitch angle than a pitch and the pitch angle of the middle concentric region, wherein the pitch angle of the proximal and distal concentric end regions is between 50 degrees and 90 degrees and the pitch angle of the middle concentric region is 25 degrees to 70 degrees when the tracheobronchial stent is in a same state, and wherein an outer diameter of the middle concentric region is dimensioned to hold open the tracheobronchial passageway; and
a first treatment agent and a second treatment agent disposed at least one of on and within at least a portion of the tracheobronchial stent, wherein the first and second treatment agents are subjected to controlled release, and wherein the first treatment agent is operable to treat mucous plugging and the second treatment agent is operable to treat granulation tissue formation.
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Abstract
Devices and methods for treating a diseased tracheobronchial region in a mammal. The device can be a stent which can include a sustained-release material such as a polymer matrix with a treatment agent. The stent can be bioabsorbable and a treatment agent can be incorporated therewith. A treatment method can be delivery of a stent to a tracheobronchial region by a delivery device such as a catheter assembly.
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Citations
17 Claims
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1. An implantable medical device comprising:
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a bioabsorbable tracheobronchial stent adapted to be positioned in a tracheobronchial passageway from a throat to lungs of a mammal, wherein the tracheobronchial stent is operable to hold open the tracheobronchial passageway from the throat to the lungs, the tracheobronchial stent having a generally tubular body comprising a single coiled fiber, the generally tubular body having a proximal concentric end region, a middle concentric region, and a distal concentric end region, wherein the proximal and distal concentric end regions each have a greater pitch and a greater pitch angle than a pitch and the pitch angle of the middle concentric region, wherein the pitch angle of the proximal and distal concentric end regions is between 50 degrees and 90 degrees and the pitch angle of the middle concentric region is 25 degrees to 70 degrees when the tracheobronchial stent is in a same state, and wherein an outer diameter of the middle concentric region is dimensioned to hold open the tracheobronchial passageway; and a first treatment agent and a second treatment agent disposed at least one of on and within at least a portion of the tracheobronchial stent, wherein the first and second treatment agents are subjected to controlled release, and wherein the first treatment agent is operable to treat mucous plugging and the second treatment agent is operable to treat granulation tissue formation. - View Dependent Claims (2, 3, 4, 5)
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6. An implantable medical device comprising:
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a bioabsorbable tracheobronchial stent adapted to be positioned in a tracheobronchial passageway from a throat to lungs of a mammal, wherein the bioabsorbable tracheobronchial stent is operable to hold open the tracheobronchial passageway from the throat to the lungs, and has a generally tubular body comprising a single coiled fiber, the generally tubular body having a proximal concentric end region, a middle concentric region, and a distal concentric end region, wherein the middle concentric region is operable to hold open the tracheobronchial passageway, and wherein the proximal and distal concentric end regions have a pitch angle of between 50 degrees and 90 degrees and the middle concentric region has a pitch angle of 25 degrees to 70 degrees when the tracheobronchial stent is in a radially expanded state, a pitch and the pitch angle of the proximal concentric end region and the distal concentric end region are greater than a pitch and the pitch angle of the middle concentric region; and a first treatment agent and a second treatment agent each disposed at least one of on and within at least a portion of the tracheobronchial stent, wherein the first and second treatment agents (a) are subjected to controlled release and (b) the first treatment agent is to treat mucous plugging and the second treatment agent is to treat granulation tissue formation. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification