Fluid associated with adult stem cells for medical, cosmetic, and veterinary use
First Claim
1. A method for treating a condition associated with damaged or diseased tissue in a patient, the method comprising administering to the patient a therapeutically effective amount of fluid isolated from a granuloma induced by a foreign body implanted under the skin or in the omentum of a live mammal, wherein the fluid so obtained contains albumin, globulins and at least 2 ng/mL of vascular endothelial growth factor (VEGF), and exceeds FBS in potency for promoting the growth of HK and primary mesangial cells in culture media, and the method results in an improvement in the patient'"'"'s condition.
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Abstract
Apparatus and process to create, expand, and localize the population of stem cells in adult tissues by placing a foreign body either in omentum or in the subcutaneous tissue. The apparatus 1) traps the granulation fluid, cells a fluid rich in a myriad of growth factors, 2) mobilizes and concentrates free-floating stem cells in the granulation fluid, and 3) stimulates the growth of a new tissue around the apparatus, which provides another source of stem cells. Stem cells obtained by this process can be used as freshly isolated or after culturing, which can be used for wound healing, treating diseases, and regenerating organs in animals and humans. The granulation fluid could substitute the stem cells in many of their applications and offers the convenience of an injectable medicine for treating animal and human diseases.
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Citations
35 Claims
- 1. A method for treating a condition associated with damaged or diseased tissue in a patient, the method comprising administering to the patient a therapeutically effective amount of fluid isolated from a granuloma induced by a foreign body implanted under the skin or in the omentum of a live mammal, wherein the fluid so obtained contains albumin, globulins and at least 2 ng/mL of vascular endothelial growth factor (VEGF), and exceeds FBS in potency for promoting the growth of HK and primary mesangial cells in culture media, and the method results in an improvement in the patient'"'"'s condition.
- 23. A method for treating arthritis in a patient, the method comprising administering to the patient a therapeutically effective amount of fluid isolated from a granuloma induced by a foreign body implanted under the skin or in the omentum a live mammal, wherein the fluid so obtained contains albumin, globulins and at least 2 ng/mL of vascular endothelial growth factor (VEGF), and exceeds FBS in potency for promoting the growth of HK and primary mesangial cells in culture media, and the method results in an improvement of the arthritic condition.
Specification