Nerve cuff with pocket for leadless stimulator

• US 9,174,041 B2
• Filed: 11/07/2014
• Issued: 11/03/2015
• Est. Priority Date: 06/09/2009
• Status: Active Grant

• Current Assignee: Setpoint Medical Corporation
• Original Assignee: Setpoint Medical Corporation
• Inventors: Faltys, Michael A., Martin, Roy C., Scott, Steven E., Loeb, Gerald E.
• Primary Examiner(s): MALAMUD, DEBORAH LESLIE
• Application Number:
  US14/536,461
• Publication Number:
  US 20150066123A1
• Time in Patent Office: 361 Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/375 Constructional arrangements, e.g. casings
• CPC Class Codes: A61N 1/37518 Anchoring of the implants, e.g. fixation
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

An extravascular nerve cuff that is configured to hold a leadless, integral, implantable microstimulator. The nerve cuff may include a cuff body having a pocket or pouch for removably receiving the implantable device within. The nerve cuff can be secured around the nerve such that the electrodes of the device are stably positioned relative to the nerve. Furthermore, the nerve cuff drives the majority of the current from the stimulation device into the nerve, while shielding surrounding tissues from unwanted stimulation.

Claims

1. A method of implanting a leadless microstimulator in communication with a vagus nerve, the method comprising:

exposing a vagus nerve;

opening a slit of a nerve cuff having a nerve cuff body, wherein the slit opens along the length of the nerve cuff body;

placing the nerve cuff around the vagus nerve so that the nerve is within a channel extending the length of nerve cuff;

inserting a leadless microstimulator within a pocket in the nerve cuff; and

securing the slit of the nerve cuff closed so that the leadless microstimulator is in electrical communication with the nerve and electrically isolated within the nerve cuff body.

2. The method of claim 1, wherein the step of securing the opening slit of the nerve cuff closed comprises securing the slit so that the leadless microstimulator engages an internal electrical contact within the nerve cuff body.

3. The method of claim 1, wherein the leadless microstimulator engages an internal electrical contact configured to provide circumferential stimulation around the nerve within the channel.

4. The method of claim 1, wherein the step of securing comprises suturing the slit closed.

5. The method of claim 1, further comprising the step of testing the microstimulator to confirm electrical communication with the nerve.

6. The method of claim 1, wherein the step of placing the nerve cuff comprises placing an oversized nerve cuff around the vagus nerve.

7. A method of implanting a leadless microstimulator in communication with a vagus nerve, the method comprising:

exposing a vagus nerve;

opening a slit of a nerve cuff having a nerve cuff body, wherein the slit opens along the length of the nerve cuff body;

placing the nerve cuff around the vagus nerve so that the nerve is within a channel extending the length of nerve cuff;

inserting a leadless microstimulator within a pocket in the nerve cuff so that the microstimulator communicates with one or more internal electrical contacts within the nerve cuff; and

closing the slit of the nerve cuff so that the nerve is in electrical communication with the one or more internal electrical contact.

8. The method of claim 7, wherein leadless microstimulator and the internal electrical contact is configured to provide circumferential stimulation around the nerve within the channel.

9. The method of claim 7, wherein the step of closing comprises securing the slit of the nerve cuff closed.

10. The method of claim 7, wherein the step of closing comprises suturing the slit closed.

11. The method of claim 7, wherein the step of placing the nerve cuff comprises placing an oversized nerve cuff around the vagus nerve.