Neuromodulation using modulated pulse train

• US 9,174,053 B2
• Filed: 03/03/2014
• Issued: 11/03/2015
• Est. Priority Date: 03/08/2013
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Zhu, Changfang
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US14/195,632
• Publication Number:
  US 20140257428A1
• Time in Patent Office: 610 Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36178 Burst or pulse train parameters
• CPC Class Codes: A61N 1/36189 using modulation techniques
• CPC Class Codes: A61N 1/36192 Amplitude modulation
• CPC Class Codes: A61N 1/36196 Frequency modulation
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: H05K 999/99 dummy group

Abstract

A neuromodulation system comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes, a user interface configured for receiving input from a user that selects one of a plurality of different shapes of a modulating signal and/or selects one of a plurality of different electrical pulse parameters of an electrical pulse train, neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals, and pulse train modulation circuitry configured for modulating the electrical pulse train in accordance with the selected shape of the modulating signal and/or selected electrical pulse parameter of the electrical pulse train.

Claims

1. A neuromodulation system, comprising:

a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes;

neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals;

pulse train modulation circuitry configured for modulating the electrical pulse train with a modulation signal that has a defined shape; and

a user interface configured for displaying two or more shape selections for the modulation signal that may be selected by a user and for receiving a shape selection from the user of one of the shape selections to select a defined shape of the modulation signal; and

pulse train modulation circuitry configured for modulating the electrical pulse train with the defined shape of the modulation signal.

2. The neuromodulation system of claim 1, wherein one of a pulse amplitude, a pulse rate, and a pulse duration of the electrical pulse train is modulated by the amplitude of the modulation signal.

3. The neuromodulation system of claim 1, wherein the shape selections includes plurality of different predefined shapes of the modulation signal.

4. The neuromodulation system of claim 3, wherein the different predefined shapes comprises at least two of a sinusoidal wave, a triangular wave, and a ramp wave.

5. The neuromodulation system of claim 3, wherein:

the electrical pulse train has a plurality of parameters;

the user input is configured for displaying two or more parameter selections for the electrical pulse train that may be selected by the user, and for receiving at least one parameter selection from the user to define at least one parameter of the electrical pulse train to be modulated with the modulation signal that has the defined shape.

6. The neuromodulation system of claim 1, wherein the two or more parameter selections for the electrical pulse train include a pulse amplitude selection, a pulse rate selection, and a pulse duration selection.

7. The neuromodulation system of claim 1, further comprising a casing containing the plurality of electrical terminals, the user interface, the neuromodulation output circuitry, and the electrical pulse modulation circuitry.

8. A neuromodulation system, comprising:

a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes;

neuromodulation output circuitry configured for outputting the electrical pulse train to the plurality of electrical terminals;

a user interface configured for displaying two or more parameter selections for the electrical pulse train that may be selected by the user, and for receiving at least one parameter selection from the user to define at least one parameter of the electrical pulse train to be modulated with the modulation signal; and

pulse train modulation circuitry configured for modulating the at least one electrical pulse parameter of the electrical pulse train with the modulation signal.

9. The neuromodulation system of claim 8, wherein the two or more parameter selections include at least two of a pulse amplitude, a pulse rate, and a pulse duration.

10. The neuromodulation system of claim 8, further comprising a casing containing the plurality of electrical terminals, the user interface, the neuromodulation output circuitry, and the electrical pulse modulation circuitry.

11. A neuromodulation system, comprising:

a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes;

neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals;

a user interface configured for displaying two or more shape selections for the determinate modulation signal that may be selected to define a shape of a determinate modulation signal and for receiving a shape selection from the user of one of the shape selections to select the defined shape of the determinate modulation signal; and

pulse train modulation circuitry configured for modulating a pulse rate of the electrical pulse train in accordance with the determinate modulation signal.

12. The neuromodulation system of claim 11, wherein the user interface includes a control that allows a user to specific at least one limit of the defined shape of the determinate modulation signal.

13. The neuromodulation system of claim 11, wherein the user interface includes a control that allows a user to specific at least one limit of a period of the determinate modulation signal.

14. The neuromodulation system of claim 11, wherein the two or more shape selections include a plurality of different predefined shapes of the determinate modulation signal.

15. The neuromodulation system of claim 14, wherein the different shapes comprises at least two of a sinusoidal wave, a triangular wave, and a ramp wave.

16. The neuromodulation system of claim 11, further comprising a casing containing the plurality of electrical terminals, neuromodulation output circuitry, and the pulse train modulation circuitry.

17. A neuromodulation system, comprising:

a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes;

neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals;

a user interface configured for displaying two or more shape selections for the determinate modulation signal that may be selected to define the shape of the determinate modulation signal and for receiving a shape selection from the user of one of the shape selections to select the defined shape of the determinate modulation signal; and

pulse train modulation circuitry configured for modulating a pulse duration of the electrical pulse train in accordance with the determinate modulation signal.

18. The neuromodulation system of claim 17, wherein the user interface includes a control that allows a user to specific at least one limit of the defined shape of the determinate modulation signal.

19. The neuromodulation system of claim 17, wherein the user interface includes a control that allows a user to specific at least one limit of a period of the determinate modulation signal.

20. The neuromodulation system of claim 17, wherein the two or more shape selections include a plurality of different predefined shapes of the determinate modulation signal.

21. The neuromodulation system of claim 20, wherein the different shapes comprises at least two of a sinusoidal wave, a triangular wave, and a ramp wave.

22. The neuromodulation system of claim 17, further comprising a casing containing the plurality of electrical terminals, neuromodulation output circuitry, and the pulse train modulation circuitry.