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Immunogenic peptides and methods of use

  • US 9,175,057 B2
  • Filed: 02/10/2011
  • Issued: 11/03/2015
  • Est. Priority Date: 02/24/2006
  • Status: Active Grant
First Claim
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1. A method of treating a subject with a PAGE4-expressing cancer, comprising administering to the subject a therapeutically effective amount of a polypeptide, or a therapeutically effective amount of a vector comprising a nucleic acid encoding the polypeptide,wherein the amino acid sequence of the polypeptide consist of amino acids 16 to 25 of SEQ ID NO:

  • 1, (X1X2APDVVAFV), wherein amino acid X1 is a glutamine or a tryrosine and amino acid X2 is a glutamic acid or a lecuine, and wherein the vector does not encode the amino acid sequence set forth as SEQ ID NO;

    1,thereby treating the PAGE4-expressing cancer in the subject.

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