Poxviral oncolytic vectors
First Claim
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1. A method for treating a disease state, wherein a defective poxvirus whose genome is only defective of the F2L and JR2 genes is administered to a host organism or cell which is in need of such treatment.
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Abstract
A poxvirus comprising a defective F2L gene and compositions comprising such poxvirus are useful for therapeutic purposes, and more particularly for the treatment of cancer.
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6 Claims
- 1. A method for treating a disease state, wherein a defective poxvirus whose genome is only defective of the F2L and JR2 genes is administered to a host organism or cell which is in need of such treatment.
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6. A method for the treatment of cancer, comprising administering to a host organism or cell in need of such treatment, for such period of time as required to elicit the desired effect, a thus effective amount of a poxvirus whose genome is only defective of the F2L and J2R genes.
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