Methods, systems and devices for non-invasive open ventilation with gas delivery nozzles within an outer tube

• US 9,180,270 B2
• Filed: 04/02/2010
• Issued: 11/10/2015
• Est. Priority Date: 04/02/2009
• Status: Active Grant

• Current Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Original Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Inventors: Kapust, Gregory, Allum, Todd, Wondka, Anthony D., Cipollone, Joseph, Aguirre, Joey, Eghbal, Darius, Freitag, Lutz, Gerber, Anthony
• Primary Examiner(s): Anderson, Lynne
• Assistant Examiner(s): Han, Mark K
• Application Number:
  US12/753,851
• Publication Number:
  US 20100252040A1
• Time in Patent Office: 2,048 Days
• Field of Search: 128/204.18, 128/204.23, 128/204.25, 128/206.28, 128/207.13, 128/207.18, 128/204.21, 128/204.22, 128/204.24, 12820426-20428, 128/205.11, 12820513-20518, 128/205.22, 128/205.24, 128/206.21, 128/207.12
• US Class Current: 1/1
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0006 with means for creating vibrations in patients' airways
• CPC Class Codes: A61M 16/0057 Pumps therefor
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/0096 High frequency jet ventilation
• CPC Class Codes: A61M 16/0493 with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
• CPC Class Codes: A61M 16/0605 Means for improving the adaptation of the mask to the patient
• CPC Class Codes: A61M 16/0622 having an underlying cushion
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0677 Gas-saving devices therefor
• CPC Class Codes: A61M 16/0683 Holding devices therefor
• CPC Class Codes: A61M 16/0688 by means of an adhesive
• CPC Class Codes: A61M 16/0825 with ball-sockets
• CPC Class Codes: A61M 16/0841 for sampling
• CPC Class Codes: A61M 16/0858 Pressure sampling ports
• CPC Class Codes: A61M 16/0875 Connecting tubes
• CPC Class Codes: A61M 16/0883 Circuit type
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 16/127 : by Venturi effect, i.e. entrainment mixers
• CPC Class Codes: A61M 16/16 : Devices to humidify the respiration air A61M16/1045 takes precedence
• CPC Class Codes: A61M 16/201 : Controlled valves
• CPC Class Codes: A61M 16/208 : Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2016/0015 : inhalation detectors
• CPC Class Codes: A61M 2016/0021 : with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0024 : with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2016/0027 : pressure meter
• CPC Class Codes: A61M 2016/0036 : in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0661 : with customised shape
• CPC Class Codes: A61M 2202/0007 : introduced into the body
• CPC Class Codes: A61M 2202/0208 : Oxygen
• CPC Class Codes: A61M 2202/03 : Gases in liquid phase, e.g. cryogenic liquids
• CPC Class Codes: A61M 2205/0205 : Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
• CPC Class Codes: A61M 2205/17 : with redundant control systems
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2230/40 : Respiratory characteristics

Abstract

A non-invasive ventilation system may include at least one outer tube with a proximal lateral end of the outer tube adapted to extend to a side of a nose. The at least one outer tube may also include a throat section. At least one coupler may be located at a distal section of the outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril. At least one jet nozzle may be positioned within the outer tube at the proximal lateral end and in fluid communication with a pressurized gas supply. At least one opening in the distal section may be adapted to be in fluid communication with the nostril. At least one aperture in the at least one outer tube may be in fluid communication with ambient air. The at least one aperture may be in proximity to the at least one jet nozzle.

Claims

1. A non-invasive ventilation system, the system comprising:

at least one outer tube with a proximal lateral end of the at least one outer tube adapted to extend to a side of a nose, wherein the at least one outer tube includes a wall and a throat section;

at least one coupler at a distal section of the at least one outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril;

at least one jet nozzle positioned within the at least one outer tube at the proximal lateral end and in fluid communication with a pressurized gas supply;

at least one pressure tap disposed within the at least one outer tube in fluid communication with a transducer;

at least one opening in the distal section adapted to be in fluid communication with the at least one nostril; and

at least one aperture defined through the wall of the at least one outer tube in fluid communication with ambient air, wherein the at least one aperture is in downstream proximity to the at least one pressure tap.

2. The system of claim 1, wherein the at least one outer tube further includes a first outer tube and a second outer tube extending in substantially opposite directions.

3. The system of claim 2, wherein at least one of the at least one jet nozzle is positioned within the first outer tube and another of the at least one jet nozzle is positioned within the second outer tube.

4. The system of claim 2, wherein the first outer tube is separated from the second outer tube by a divider.

5. The system of claim 1, wherein the at least one outer tube is a manifold.

6. The system of claim 5, wherein a gas flow path within the manifold is curved and devoid of abrupt angles and corners.

7. The system of claim 1, wherein the at least one coupler is a nasal pillow.

8. The system of claim 1, wherein the at least one coupler is adapted to seal the at least one nostril such that a patient spontaneously breathes through the at least one aperture.

9. The system of claim 1, wherein a distal tip of the at least one jet nozzle is positioned at the at least one aperture.

10. The system of claim 1, wherein the at least one jet nozzle directs pressurized gas in a substantially parallel direction with ambient air entering from the at least one aperture.

11. The system of claim 1, further comprising at least one secondary aperture in the at least one outer tube.

12. The system of claim 1, wherein the at least one jet nozzle directs pressurized gas coaxially to a primary gas flow pathway.

13. The system of claim 1, further comprising a filter.

14. The system of claim 1, further comprising at least one sensor for sensing spontaneous respiration.

15. The system of claim 14, further comprising a ventilator for delivering pressurized gas in synchrony with phases of breathing.

16. The system of claim 1, wherein a cross sectional area of the at least one aperture is larger than a cross sectional area of the throat section.

17. The system of claim 1, wherein the system further comprises a wearable ventilator.

18. The system of claim 1, wherein the system further comprises a ventilator, the ventilator comprises a control unit, and wherein the control unit adjusts an output of the ventilator to match a patient'"'"'s ventilation needs based on information from at least one sensor.

19. The system of claim 1, wherein the system further comprises a ventilator, the ventilator comprises a control unit, and the control unit comprises a speaking mode sensing system, and wherein the control unit adjusts an output of the ventilator while the patient is speaking to not be asynchronous with a patient'"'"'s spontaneous breathing.

20. The system of claim 1, wherein the system further comprises a ventilator, the ventilator comprises a control unit, and the control unit comprises an apnea or hypopnea sensing system, and wherein the control unit adjusts an output of the ventilator according to apnea or hypopnea.

21. The system of claim 1, wherein the at least one outer tube comprises sound reduction features selected from the group consisting of:

a secondary aperture, a filter for the at least one aperture, textured surfaces, a muffler, sound absorbing materials, an angled jet nozzle, non-concentric jet nozzle positions, and combinations thereof.

22. The system of claim 1, wherein the system further comprises a ventilator, and the at least one outer tube comprises at least one gas delivery circuit in fluid communication with the ventilator.

23. The system of claim 22, wherein the at least one gas delivery circuit is bifurcated.

24. The system of claim 23, wherein the at least one outer tube further comprises a manifold in fluid communication with the ventilator, the manifold comprising at least one lateral proximal end in fluid communication with the at least one gas delivery circuit.

25. The system of claim 24, wherein at least one of the at least one aperture defined through the wall of the at least one outer tube in fluid communication with ambient air is disposed in the at least one lateral proximal end of the manifold.

26. The system of claim 25, wherein at least one of the at least one jet nozzle is aligned in parallel with each of the at least one gas delivery circuit and supplies ventilation gas proximate to the at least one of the at least one aperture defined through the wall of the at least one outer tube in fluid communication with ambient air.

27. The system of claim 26, wherein the ventilation gas and entrained ambient air elevates lung pressure, elevates lung volume, decreases work of breathing or increases airway pressure.

28. The system of claim 22, wherein the transducer is disposed within the ventilator.