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Fluidic cartridge for detecting chemicals in samples, in particular for performing biochemical analyses

  • US 9,180,451 B2
  • Filed: 06/27/2011
  • Issued: 11/10/2015
  • Est. Priority Date: 06/28/2010
  • Status: Active Grant
First Claim
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1. A fluidic cartridge for detecting chemicals in samples, comprising:

  • an integrated device having a plurality of detecting regions configured to bind to target chemicals;

    an interface unit electrically coupled to the integrated device and including a signal processing stage and external contact regions;

    a supporting element carrying the integrated device and the interface unit;

    a reaction chamber facing the detecting regions;

    fluidic paths coupled to the reaction chamber;

    a waste reservoir;

    a valve selectively coupling the waste reservoir to the reaction chamber; and

    a casing hermetically housing part of the supporting element with the integrated device, the reaction chamber, the fluidic paths, the waste reservoir, and the valve, the casing including;

    a sample feeding hole and a washing feeding hole, the sample feeding hole and the washing feeding hole being coupled to the reaction chamber by the fluidic paths; and

    first and second closures respectively closing the sample feeding hole and the washing feeding hole, wherein;

    the integrated device is fixed to a first side of the supporting element,the waste reservoir is arranged on a second side of the supporting element, andthe valve comprises a weakened area of the supporting element and a perforating element extending in the casing on the second side of the supporting element and having a perforating tip, the perforating element being in fluidic connection with the waste reservoir and being actuatable between a rest configuration and a perforating configuration, wherein the rest configuration is a configuration in which the perforating tip extends at a distance from the weakened area, and the perforating configuration is a configuration in which the perforating element extends through the weakened area and provides a fluid connection between the reaction chamber and the waste reservoir.

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