Methods and systems for qualifying physiological values based on metrics

• US 9,186,109 B2
• Filed: 09/11/2012
• Issued: 11/17/2015
• Est. Priority Date: 09/11/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Engelbrecht, Pirow, Rodriguez-Llorente, Fernando
• Primary Examiner(s): ZEMAN, MARY K
• Application Number:
  US13/609,629
• Publication Number:
  US 20140073875A1
• Time in Patent Office: 1,162 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7228 Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal modulation H03C
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity

Abstract

A physiological monitoring system may process a physiological signal such a photoplethysmograph signal from a subject. The system may determine physiological information, such as a physiological rate, from the physiological signal. The system may use search techniques and qualification techniques to determine one or more initialization parameters. The initialization parameters may be used to calculate and qualify a physiological rate. The system may use signal conditioning to reduce noise in the physiological signal and to improve the determination of physiological information. The system may use qualification techniques to confirm determined physiological parameters. The system may also use autocorrelation techniques, cross-correlation techniques, fast start techniques, and/or reference waveforms when processing the physiological signal.

Claims

1. A subject monitoring pulse oximetry system for updating a display rate for a subject, comprising:

a pulse oximetry sensor configured to detect light attenuated by the subject and generate a photoplethysmographic (PPG) signal based on the detected attenuated light;

a pulse oximeter coupled to the pulse oximetry sensor; and

a display coupled to the pulse oximeter, wherein the display is configured to display the display rate for the subject, wherein;

the pulse oximeter is configured to;

determine a value indicative of a physiological rate of the subject;

determine a first metric based on the PPG signal;

perform a filtering calculation based on the PPG signal to generate a filtered PPG signal, wherein the filtering calculation comprises a high-pass filter having a cut-off set at a frequency higher than a frequency corresponding to the value indicative of the physiological rate of the subject;

determine a second metric based on the filtered PPG signal;

qualify the value indicative of the physiological rate of the subject based on the first and second metrics; and

update the display rate on the display based on the qualified value indicative of the physiological rate.

2. The system of claim 1, wherein the-cut-off is set at a frequency corresponding to approximately double the value indicative of the physiological rate.

3. The system of claim 1, wherein the first metric comprises one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

4. The system of claim 1, wherein the second metric comprises one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

5. The system of claim 1, wherein the pulse oximeter is further configured to compare the first metric to the second metric.

6. The system of claim 1, wherein the pulse oximeter is further configured to:

determine a ratio of the first metric to the second metric;

compare the ratio to a threshold; and

qualify the value of indicative of the physiological rate based on the comparison of the ratio to the threshold.

7. The system of claim 1, wherein the physiological rate is a pulse rate.

8. A pulse oximetry processing module for updating a display rate for a subject on a display, wherein the pulse oximetry processing module is coupled to the display and comprises non-transitory computer readable media configured to store instructions that instruct the pulse oximetry processing module to:

receive a photoplethysmographic (PPG) signal from a pulse oximetry sensor, wherein the pulse oximetry sensor detects light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

determine a value indicative of a physiological rate of the subject;

determine a first metric based on the PPG signal;

perform a filtering calculation based on the PPG signal to generate a filtered PPG signal, wherein the filtering calculation comprises a high-pass filter having a cut-off set at a frequency higher than a frequency corresponding to the value indicative of the physiological rate of the subject;

determine a second metric based on the filtered PPG signal;

qualify the value indicative of the physiological rate of the subject based on the first and second metrics; and

update the display rate on the display based on the qualified value indicative of the physiological rate.

9. The pulse oximetry processing module of claim 8, wherein the cut-off is set at a frequency corresponding to approximately double the value indicative of the physiological rate.

10. The pulse oximetry processing module of claim 8, wherein the first metric comprises one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

11. The pulse oximetry processing module of claim 8, wherein the second metric comprises one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

12. The pulse oximetry processing module of claim 8, wherein the non-transitory computer-readable media is further configured to store instructions that instruct the pulse oximetry processing module to compare the first metric to the second metric.

13. The pulse oximetry processing module of claim 8, wherein the non-transitory computer-readable media is further configured to store instructions that instruct the pulse oximetry processing module to:

determine a ratio of the first metric to the second metric;

compare the ratio to a threshold; and

qualify the value of indicative of the physiological rate based on the comparison of the ratio to the threshold.

14. The pulse oximetry processing module of claim 8, wherein the physiological rate is a pulse rate.

15. A method for updating a display rate for a subject on a display, comprising:

receiving, using a pulse oximeter, a photoplethysmographic (PPG) signal from a pulse oximetry sensor, wherein the pulse oximetry sensor detects light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

determining, using the pulse oximeter, a value indicative of a physiological rate of the subject;

determining, using the pulse oximeter, a first metric based on the PPG signal;

performing, using the pulse oximeter, a filtering calculation based on the PPG signal to generate a filtered PPG signal, wherein the filtering calculation comprises a high-pass filter having a cut-off set at a frequency higher than a frequency corresponding to the value indicative of the physiological rate of the subject;

determining, using the pulse oximeter, a second metric based on the filtered PPG signal;

qualifying, using the pulse oximeter, the value indicative of the physiological rate of the subject based on the first and second metrics; and

updating, using the pulse oximeter, the display rate on the display based on the qualified value indicative of the physiological rate.

16. The method of claim 15, wherein the cut-off is set at a frequency corresponding to approximately double the value indicative of the physiological rate.

17. The method of claim 15, wherein determining the first metric comprises determining one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

18. The method of claim 15, wherein determining the second metric comprises determining one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

19. The method of claim 15, further comprising comparing the first metric to the second metric.

20. The method of claim 15, further comprising:

determining a ratio of the first metric to the second metric; and

comparing the ratio to a threshold, wherein qualifying the value indicative of the physiological rate comprises qualifying the value indicative of the physiological rate based on the comparison of the ratio to the threshold.

21. The method of claim 15, wherein the physiological rate is a pulse rate.

22. A non-transitory computer-readable medium for use in updating a display rate for a subject on a display, the non-transitory computer-readable medium comprising:

computer program instructions recorded thereon for causing a pulse oximeter to;

receiving an intensity receive a photoplethysmographic (PPG) signal from a pulse oximetry sensor, wherein the pulse oximetry sensor detects light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

determine a value indicative of a physiological rate of the subject;

determine a first metric based on the PPG signal;

perform a filtering calculation based on the PPG signal to generate a filtered PPG signal, wherein the filtering calculation comprises a high-pass filter having a cut-off set at a frequency higher than a frequency corresponding to the value indicative of the physiological rate of the subject;

determine a second metric based on the filtered PPG signal;

qualify the value indicative of the physiological rate of the subject based on the first and second metrics; and

update the display rate on the display based on the qualified value indicative of the physiological rate.

23. The non-transitory computer-readable medium of claim 22, wherein the cut-off is set at a frequency corresponding to approximately double the value indicative of the physiological rate.

24. The non-transitory computer-readable medium of claim 22, wherein the first metric comprises one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

25. The non-transitory computer-readable medium of claim 22, wherein the second metric comprises one of a standard deviation, root-mean-square deviation, an amplitude, a sum, and an integral.

26. The non-transitory computer-readable medium of claim 22, comprising further computer program instructions recorded thereon for causing the pulse oximeter to compare the first metric to the second metric.

27. The non-transitory computer-readable medium of claim 22, comprising further computer program instructions recorded thereon for causing the pulse oximeter to:

determine a ratio of the first metric to the second metric; and

compare the ratio to a threshold, wherein qualifying the value indicative of the physiological rate comprises qualifying the value indicative of the physiological rate based on the comparison of the ratio to the threshold.

28. The non-transitory computer-readable medium of claim 22, wherein the physiological rate is a pulse rate.