Annuloplasty devices and methods of delivery therefor

• US 9,192,472 B2
• Filed: 06/15/2009
• Issued: 11/24/2015
• Est. Priority Date: 06/16/2008
• Status: Active Grant

• Current Assignee: Valtech Cardio Ltd (Edwards Lifesciences Corporation)
• Original Assignee: Valtech Cardio Ltd (Edwards Lifesciences Corporation)
• Inventors: Gross, Amir, Beinart, Iftah, Eliachar, Eliahu, Lilach, Nir, Grossfeld, Ram, Golom, Dmitry, Meyer-Brodnitz, Gideon, Mosaiuf, Arnon
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): Ganesan, Suba
• Application Number:
  US12/996,954
• Publication Number:
  US 20110166649A1
• Time in Patent Office: 2,353 Days
• Field of Search: 623/1.11, 623/1.23, 623/2.1, 623/2.11, 623/2.36, 623/2.37, 623/2.38, 623/2.39, 623/2.4, 623/2.41
• US Class Current: 1/1
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61F 2/2442 Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2/2466 Delivery devices therefor
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2250/001 for adjusting a diameter

Abstract

Apparatus is provided, including a tube (421) shaped to define a tube lumen at least one implant (100) reversibly coupled to the tube (421), and configured for implantation within a body of a patient. The apparatus also comprises two or more longitudinal guide members (470) disposed at least in part along a distal portion of the tube (421), the longitudinal guide members (470) having distal portions thereof configured to be reversibly coupled to the implant (100), and arranged such that application of a force to a first one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a first location along the implant (100), and application of a force to a second one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a second location along the implant (100). Other embodiments are also described.

Claims

1. A method for facilitating treatment of a native atrioventricular valve of a body of a patient, the valve including an annulus and at least first and second leaflets, comprising:

advancing an advancement catheter, which includes a tube shaped to define a tube lumen, toward the valve of the patient;

advancing toward the valve at least one implant reversibly coupled to the tube by two or more longitudinal guide members, wherein respective distal portions of the longitudinal guide members are reversibly coupled to the implant, and respective portions of the longitudinal guide members are disposed at least in part along a distal portion of the tube;

positioning the implant against the annulus of the patient;

steering the distal portion of the tube toward, and the advancement catheter into contact with, a first location along the implant by pulling a first one of the two or more longitudinal guide members; and

steering the distal portion of the tube toward, and the advancement catheter into contact with, a second location along the implant by pulling a second one of the two or more longitudinal guide members.

2. The method according to claim 1, further comprising:

anchoring the implant at the first location along the implant to the annulus by advancing a first anchor from the tube, through the implant and into tissue of the annulus, while the distal portion of the tube is steered toward the first location along the implant; and

anchoring the implant at the second location along the implant to the annulus by advancing a second anchor from the tube, through the implant and into tissue of the annulus, while the distal portion of the tube is steered toward the second location along the implant.

3. The method according to claim 1,

wherein the advancement catheter includes a tapered distal end,

wherein steering the distal portion of the tube toward, and the advancement catheter into contact with, the first location along the implant comprises steering the distal portion of the tube toward, and the tapered distal end into contact with, the first location along the implant, and

wherein steering the distal portion of the tube toward, and the advancement catheter into contact with, the second location along the implant comprises steering the distal portion of the tube toward, and the tapered distal end into contact with, the second location along the implant.

4. The method according to claim 1, wherein pulling the first longitudinal guide member comprises providing slack to the other longitudinal guide members other than the first longitudinal guide member, by releasing the other longitudinal guide members, such that the other longitudinal guide members do not resist movement of the tube toward the first location along the implant.

5. The method according to claim 1, wherein advancing the implant comprises advancing toward the valve the implant while the respective portions of the two or more longitudinal guide members are reversibly coupled to the distal portion of the tube.

6. The method according to claim 5, wherein advancing the implant comprises advancing toward the valve the implant while the respective portions of the two or more longitudinal guide members are reversibly coupled to the distal portion of the tube at the same time.

7. The method according to claim 5, wherein advancing the implant comprises advancing toward the valve the implant while the respective portions of the two or more longitudinal guide members are reversibly coupled to a wall of the distal portion of the tube.

8. The method according to claim 7, wherein advancing the implant comprises advancing toward the valve the implant while the respective portions of the two or more longitudinal guide members are reversibly coupled to the wall at a plurality of circumferential locations distributed around the distal portion of the tube.

9. The method according to claim 5, wherein advancing the implant comprises advancing toward the valve the implant while the respective portions of the two or more longitudinal guide members are reversibly coupled to an external surface of the distal portion of the tube.

10. The method according to claim 9,

wherein a ring surrounds at least a portion of the tube, the ring being shaped to define two or more channels through which the respective portions of the two or more longitudinal guide members respectively pass when reversibly coupled to the implant, and

wherein advancing the implant comprises advancing toward the valve the implant while the ring reversibly couples the respective portions of the two or more longitudinal guide members to the external surface of the distal portion of the tube.

11. The method according to claim 10, wherein the ring is configured to rotate with respect to the tube.