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Dry powder inhaler and system for drug delivery

  • US 9,192,675 B2
  • Filed: 07/30/2013
  • Issued: 11/24/2015
  • Est. Priority Date: 06/13/2008
  • Status: Active Grant
First Claim
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1. A drug delivery system comprising an inhaler, a powder container, comprising fumaryl diketopiperazine (FDKP) microparticles comprising a trans-FDKP isomer content of about 45% to about 65% and a drug, wherein the aerodynamic performance of the microparticles is improved as compared to fumaryl diketopiperazine microparticles having a trans isomer content outside of said trans isomer content of about 45% to about 65%;

  • andwherein in use about 10% to 70% of an air flow exiting the inhaler and entering a user passes through the powder container and about 90% to 30% of said air flow bypasses the powder container.

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