Shunt-current reduction techniques for an implantable therapy system

• US 9,192,769 B2
• Filed: 08/31/2009
• Issued: 11/24/2015
• Est. Priority Date: 10/31/2008
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Donofrio, William T., Burnes, John E., Krause, Paul G., Arne, Gerald P., Zhou, Xiaohong
• Primary Examiner(s): Heller, Tammie K
• Application Number:
  US12/551,331
• Publication Number:
  US 20100114211A1
• Time in Patent Office: 2,276 Days
• Field of Search: 607/9, 607/63
• US Class Current: 1/1
• CPC Class Codes: A61N 1/086 Magnetic resonance imaging [MRI] compatible leads
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/3718 Monitoring of or protection against external electromagnetic fields or currents
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient

Abstract

Techniques for minimizing interference between the first and second medical devices or between the different therapy modules of a common medical device are described herein. In some examples, a medical device may include shunt-current mitigation circuitry and/or at least one clamping structure that helps minimize or even eliminate shunt-current that feeds into a first therapy module of the medical device via one or more electrodes electrically connected to the first therapy module. The shunt-current may be generated by the delivery of electrical stimulation by a second therapy module. The second therapy module may be enclosed in a common housing with the first therapy module or may be separate, e.g., a part of a separate medical device.

Claims

1. A system comprising:

a first therapy module comprising a housing and a signal generator enclosed within the housing, wherein the signal generator is configured to generate and deliver electrical stimulation to a first tissue site within a patient via a first electrode electrically connected to the signal generator;

a second therapy module configured to deliver electrical stimulation to a second tissue site within the patient;

a second, nontherapeutic electrode that is not used by the second therapy module for the delivery of the electrical stimulation by the second therapy module; and

a clamping structure configured to electrically connect the second, nontherapeutic electrode to the housing of the first therapy module, wherein the clamping structure is configured to reduce a shunt-current introduced into the first therapy module via the first electrode, and wherein the shunt-current is generated by the delivery of electrical stimulation by the second therapy module.

2. The system of claim 1, wherein the clamping structure is configured to electrically connect the second, nontherapeutic electrode to the housing of the first therapy module when a voltage gradient generated by the electrical stimulation delivered by the second therapy module to the second tissue site is greater than or equal to a threshold voltage value, wherein the voltage gradient generates the shunt-current, and wherein the clamping structure is configured to provide a lower impedance electrical path for the shunt-current than an electrical path through the first electrode.

3. The system of claim 1, wherein the clamping structure comprises one or more of a diode, a Zener diode, a gas plasma arrestor, a varistor, or a combination thereof.

4. The system of claim 1, wherein the second, nontherapeutic electrode comprises a conductive surface area that is larger than a conductive surface area of the first electrode.

5. The system of claim 1, wherein the second, nontherapeutic electrode is configured to be implanted in one of a subcutaneous layer, a sub-muscular location, and intravenous location of the patient.

6. The system of claim 1, wherein the housing substantially encloses the first and second therapy modules.

7. The system of claim 1, wherein the housing comprises a first outer housing, wherein the system further comprises:

a first implantable medical device (IMD) comprising the first outer housing, the first outer housing enclosing the first therapy module; and

a second IMD comprising a second outer housing enclosing the second therapy module, wherein the first and second outer housings are physically separate from each other and are configured to be separately implanted within the patient.

8. The system of claim 1, wherein the first therapy module comprises an electrical stimulation module configured to deliver electrical stimulation via the signal generator to the first tissue site, wherein the first tissue site comprises at least one of a nonmyocardial tissue site or a nonvascular cardiac tissue site within the patient, and the second therapy module comprises a cardiac therapy module that is configured to deliver at least one of pacing, cardioversion or defibrillation therapy to the second tissue site, and wherein the second tissue site comprises a heart of the patient.

9. The system of claim 1, wherein the second therapy module comprises at least one of an automatic external defibrillator, an implantable defibrillator, and intravenous defibrillator.

10. The system of claim 1, wherein the first therapy module comprises a cardiac therapy module that is configured to deliver at least one of pacing, cardioversion or defibrillation therapy to a heart of the patient, and the second therapy module comprises an electrical stimulation module configured to deliver electrical stimulation to at least one of a nonmyocardial tissue site or a nonvascular cardiac tissue site within the patient.

11. The system of claim 1, further comprising a shunt-current mitigation circuitry coupled to the first electrode, wherein the shunt-current mitigation circuitry is configured to reduce the shunt-current that is introduced into the first therapy module via the first electrode.

12. The system of claim 11, wherein the shunt-current mitigation circuitry comprises:

a monitor electrically coupled to the first electrode via a wire, wherein the monitor is configured to monitor an electrical parameter value at the first electrode; and

a switch coupled to the monitor,

wherein the monitor is configured to open the switch when the electrical parameter value is greater than or equal to a threshold value.

13. The system of claim 12, further comprising a third electrode, wherein the electrical parameter value comprises at least one of a voltage at the first electrode, a current through the first electrode, or a voltage across at least the first and third electrodes.

14. The system of claim 12, wherein the monitor comprises a voltage monitor.

15. The system of claim 12, wherein the monitor comprises a current monitor.

16. The system of claim 12, wherein the wire comprises a resistive wire comprising a resistance of approximately 10 ohms to approximately 10 kiloohms.

17. The system of claim 12, wherein the switch comprises a relay.

18. The system of claim 11, wherein the shunt-mitigation circuitry comprises a resistor electrically connected to the first electrode.

19. The system of claim 18, wherein the shunt-mitigation circuitry further comprises a switch in parallel with the resistor, wherein the first therapy module is configured to toggle the switch closed during the delivery of the delivery of electrical stimulation by the first therapy module.

20. The system of claim 11, wherein the shunt-mitigation circuitry comprises a diode coupled to the first electrode.

21. The system of claim 11, wherein the shunt-mitigation circuitry comprises a current limiter coupled to the first electrode.

22. The system of claim 21, wherein the current limiter comprises at least one of a fuse, a resettable fuse, or a bimetallic circuit breaker.

23. The system of claim 11, further comprising an implantable medical lead that is electrically connected to the first therapy module and comprising the first electrode, wherein the shunt-current mitigation circuitry is located within at least one of the first therapy module, a connector that electrically connects the implantable medical lead to the first therapy module, or the implantable medical lead.

24. The system of claim 11, further comprising a processor within the first therapy module, wherein the shunt-current mitigation circuitry comprises:

a monitor electrically coupled to the first electrode via a wire, wherein the monitor is configured to monitor an electrical parameter value at the electrode; and

a switch coupled to the monitor, wherein the processor is configured to open the switch when the electrical parameter value is greater than or equal to a threshold value.

25. The system of claim 1, further comprising a switch located between the first electrode and the signal generator of the first therapy module, wherein the first therapy module comprises a processor, wherein the second therapy module is configured to transmit a communication signal to the processor that indicates prospective therapy delivery to the patient by the second therapy module, and wherein the processor is configured to open the switch in response to receiving the communication signal from the second therapy module.

26. The system of claim 1, wherein the first electrode is electrically coupled to the signal generator via an inductive wire.

27. The system of claim 1, wherein the clamping structure comprises a first clamping structure, the system further comprising a second clamping structure electrically connected to the first electrode, wherein a threshold voltage value that activates the second clamping structure is greater than a threshold voltage value that activates the first clamping structure, and wherein the second clamping structure is substantially similar to the first clamping structure.

28. A method comprising:

sensing a voltage gradient via a first, nontherapeutic electrode that is coupled to a housing of a first therapy module via a clamping structure, wherein the voltage gradient is generated by delivery of electrical stimulation by a second therapy module via one or more electrodes coupled to the second therapy module, and wherein the first, nontherapeutic electrode is not one of the electrodes used by the second therapy module for the delivery of the electrical stimulation by the second therapy module;

activating the clamping structure when the sensed voltage gradient is greater than a threshold voltage value; and

reducing a shunt-current that is introduced into the first therapy module via a second electrode that is coupled to a signal generator of the first therapy module,

wherein the shunt-current is generated by the delivery of electrical stimulation by the second therapy module, and wherein activating the clamping structure reduces the shunt-current introduced into the first therapy module via the second electrode.

29. The method of claim 28, wherein the first, nontherapeutic electrode and the activated clamping structure provide a lower impedance electrical path for the shunt-current than an electrical path through the second electrode.

30. The method of claim 28, wherein the clamping structure comprises one or more of a diode, a Zener diode, a gas plasma arrestor, a varistor, or a combination thereof.

31. The method of claim 28, wherein the first, nontherapeutic electrode comprises a conductive surface area that is larger than a conductive surface area of the second electrode.

32. The method of claim 28, wherein the first, nontherapeutic electrode is configured to be implanted in one of a subcutaneous layer, a sub-muscular location, and intravenous location of the patient.

33. The method of claim 28, further comprising:

monitoring an electrical parameter value at the second electrode;

determining whether the electrical parameter value is greater than or equal to a threshold value; and

opening a switch that electrically connects the second electrode and the first therapy module if the electrical parameter value is greater than or equal to the threshold value.

34. The method of claim 28, further comprising:

transmitting a communication signal from the second therapy module to the first therapy module, wherein the communication signal indicates prospective therapy delivery by the second therapy module; and

toggling open a switch located between the second electrode and the signal generator in response to the communication signal.

35. A system comprising:

means for sensing a voltage gradient, the means for sensing being coupled to a housing of a first therapy module via a clamping structure, wherein the voltage gradient is generated by delivery of electrical stimulation by a second therapy module via one or more electrodes coupled to the second therapy module, and wherein the means for sensing is not configured for the delivery of the electrical stimulation by the second therapy module; and

means for activating the clamping structure when the sensed voltage gradient is greater than a threshold voltage value

for reducing a shunt-current that is introduced into the first therapy module via an electrode that is coupled to a signal generator of the first therapy module,

wherein the shunt-current is generated by the delivery of electrical stimulation by the second therapy module.

36. The system of claim 35, wherein the means for sensing comprises a first, nontherapeutic electrode, wherein the electrode comprises a second electrode, and wherein the first, nontherapeutic electrode and the activated clamping structure provide a lower impedance electrical path for the shunt-current than an electrical path through the second electrode.

37. The system of claim 35, wherein the clamping structure comprises one or more of a diode, a Zener diode, a gas plasma arrestor, a varistor, or a combination thereof.

38. The system of claim 35, wherein the means for sensing comprises a first, nontherapeutic electrode, wherein the electrode comprises a second electrode, and wherein the first, nontherapeutic electrode comprises a conductive surface area that is larger than a conductive surface area of the second electrode.

39. The system of claim 35, wherein the means for sensing comprises a nontherapeutic electrode, and wherein the nontherapeutic electrode is configured to be implanted in one of a subcutaneous layer, a sub-muscular location, and intravenous location of the patient.

40. The system of claim 35, further comprising:

means for monitoring an electrical parameter value at the electrode;

means for determining whether the electrical parameter value is greater than or equal to a threshold value; and

means for opening a switch that electrically connects the electrode and the first therapy module if the electrical parameter value is greater than or equal to the threshold value.

41. The system of claim 35, further comprising:

means for transmitting a communication signal from the second therapy module to the first therapy module, wherein the communication signal indicates prospective therapy delivery by the second therapy module; and

means for toggling open a switch located between the electrode and the signal generator in response to the communication signal.