Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
First Claim
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1. A method, comprising:
- exposing target cells in a visual pathway to one or more sources of narrowband, multichromatic radiation having at least one dominant emissive wavelength between about 300 nm and about 1600 nm; and
delivering an energy fluence to the target cells of less than or equal to 4.0 J/cm2, wherein the energy fluence received at the target cells is from about 1 nanojoule/cm2 to about 1 J/cm2.
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Abstract
Disclosed is a system and method for treatment of cells and, in particular, visual pathway disorders. More particularly, the disclosed invention is directed toward the photomodulation and/or photorejuvenation of retinal epithelial cells, to treat a variety of vision disorders. The process of treating retinal cells to reduce or reverse the effects of visual pathway disorders employs a narrowband source of multichromatic light applied to the retinal cells to deliver a very low energy fluence.
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Citations
23 Claims
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1. A method, comprising:
exposing target cells in a visual pathway to one or more sources of narrowband, multichromatic radiation having at least one dominant emissive wavelength between about 300 nm and about 1600 nm; and
delivering an energy fluence to the target cells of less than or equal to 4.0 J/cm2, wherein the energy fluence received at the target cells is from about 1 nanojoule/cm2 to about 1 J/cm2.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method, comprising:
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exposing cells undergoing oxidative stress to one or more sources of light having at least one dominant emissive wavelength between about 300 nm and about 1600 nm; delivering an energy fluence to the target cells of less than or equal to 4.0 J/cm2, wherein the energy fluence received at the target cells is from about 1 nanojoule/cm2 to about 1 J/cm2; wherein a decrease in the amount of free radicals released by the target cells undergoing oxidative stress is observed. - View Dependent Claims (15, 16, 17, 18)
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19. A method, comprising:
- exposing target cells that have been subject to acute or chronic injury or degenerative changes to a one or more sources of light having at least one dominant emissive wavelength between about 300 nm and about 1600 nm;
delivering an energy fluence to the target cells of less than 4.0 J/cm2, wherein the energy fluence received at the target cells is from about 1 nanojoule/cm2 to about 1 J/cm2; andwherein a restoration of a function of the target cells prior to being subject to acute or chronic injury or degenerative changes is observed. - View Dependent Claims (20, 21, 22, 23)
- exposing target cells that have been subject to acute or chronic injury or degenerative changes to a one or more sources of light having at least one dominant emissive wavelength between about 300 nm and about 1600 nm;
Specification