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Formulation for stabilizing proteins, which is free of mammalian excipient

  • US 9,198,856 B2
  • Filed: 04/16/2010
  • Issued: 12/01/2015
  • Est. Priority Date: 04/17/2009
  • Status: Active Grant
First Claim
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1. A formulation consisting essentially of:

  • (a) hyaluronic acid,(b) a mixture of a polyalcohol and a sugar, and wherein the weight ratio of polyalcohol to sugar is from 2;

    1 to 5;

    1 (wt-%),(c) a surfactant, and(d) a Clostridium botulinum toxin,wherein the formulation is free of human serum albumin (HSA), gelatin, histidine, lysine, methionine immunoglobulins.

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