System and method for preventing hypoglycaemia in a human type 1 diabetic patient during physical activity
First Claim
1. A method for preventing hypoglycaemia in a DP-1 during physical activity, comprising the following steps:
- providing a processing unit including memory that stores a program code that performs calculations and stores parameters of a process, the process comprising the steps of;
defining of working constants and standard parameters;
introducing of patient and therapy specific parameters;
calculating of patient specific reference curves for a percentage carbohydrates consumption (% CHO);
scheduling a training session;
estimating the amount of carbohydrates (CHO) to be eaten before said physical activity;
updating in real time the residual carbohydrates still available during said physical activity; and
calculating the amount of carbohydrates to be restored after said physical activitywherein;
said step of introducing of patient and therapy specific parameters comprises the value of glucose oxidation rate approximated with a linear relationship characterized by a slope (BGm) and intercept (BGq), as a carbohydrates consumption (grams/minutes) in function of the heart rate (beats/minutes) and said step of updating in real time the residual carbohydrates still available during said physical activity comprises a calculation performed continuously of the current glucose oxidation rate calculated as the current heart rate using a linear relation and wherein a value of required carbohydrates for performing the physical activity is continuously calculated by multiplying the current glucose oxidation rate by the % CHO at the current time and wherein the amount of required carbohydrates for the physical activity is updated by accumulating the value of required carbohydrates calculated at a previous timewherein said step of defining the working constants and standard parameters comprises the steps of;
defining the number of hours of contribution of dinner insulin;
defining the relationship between effective insulinemy and percentage carbohydrates defining the standard sensibility;
defining a reference glycemic curve;
defining the type-specific insulin curves; and
defining a type-specific standard insulin dose and wherein said relationship between effective insulinemy and percentage carbohydrates is a linear relationship having a slope mpg=4.398 and intercept qpg=10.76.
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Accused Products
Abstract
A method for estimating the amount of carbohydrates needed by a DP-1 during a specific session of physical activity, comprises the following steps: defining of working constants and standard parameters; introducing of patient and therapy specific parameters, calculating of patient specific reference curves for a percentage carbohydrates consumption (% CHO); scheduling a training session; estimating the amount of carbohydrates (CHO) to be eaten before said physical activity; updating in real time the residual carbohydrates still available during said physical activity; and estimating the amount of carbohydrates to be restored after said physical activity.
8 Citations
18 Claims
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1. A method for preventing hypoglycaemia in a DP-1 during physical activity, comprising the following steps:
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providing a processing unit including memory that stores a program code that performs calculations and stores parameters of a process, the process comprising the steps of; defining of working constants and standard parameters; introducing of patient and therapy specific parameters; calculating of patient specific reference curves for a percentage carbohydrates consumption (% CHO); scheduling a training session; estimating the amount of carbohydrates (CHO) to be eaten before said physical activity; updating in real time the residual carbohydrates still available during said physical activity; and calculating the amount of carbohydrates to be restored after said physical activity wherein; said step of introducing of patient and therapy specific parameters comprises the value of glucose oxidation rate approximated with a linear relationship characterized by a slope (BGm) and intercept (BGq), as a carbohydrates consumption (grams/minutes) in function of the heart rate (beats/minutes) and said step of updating in real time the residual carbohydrates still available during said physical activity comprises a calculation performed continuously of the current glucose oxidation rate calculated as the current heart rate using a linear relation and wherein a value of required carbohydrates for performing the physical activity is continuously calculated by multiplying the current glucose oxidation rate by the % CHO at the current time and wherein the amount of required carbohydrates for the physical activity is updated by accumulating the value of required carbohydrates calculated at a previous time wherein said step of defining the working constants and standard parameters comprises the steps of; defining the number of hours of contribution of dinner insulin; defining the relationship between effective insulinemy and percentage carbohydrates defining the standard sensibility; defining a reference glycemic curve; defining the type-specific insulin curves; and defining a type-specific standard insulin dose and wherein said relationship between effective insulinemy and percentage carbohydrates is a linear relationship having a slope mpg=4.398 and intercept qpg=10.76. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. Apparatus for carrying out a method for preventing hypoglycaemia in a DP-1 during physical activity, comprising:
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a processor configured for executing program code that performs calculations and stores parameters of a process for preventing hypoglycaemia in a DP-1 patient, the process including the steps of;
defining of working constants and standard parameters including the steps of defining the number of hours of contribution of dinner insulin;
defining the relationship between effective insulinemy and percentage carbohydrates defining the standard sensibility;
defining a reference glycemic curve;
defining the type-specific insulin curves; and
defining a type-specific standard insulin dose and wherein said relationship between effective insulinemy and percentage carbohydrates is a linear relationship having a slope mpg=4.398 and intercept qpg=10.76;
introducing of patient and therapy specific parameters including the value of glucose oxidation rate approximated with a linear relationship characterized by a slope (BGm) and intercept (BGq), as a carbohydrates consumption (grams/minutes) in function of the heart rate (beats/minutes) and said step of updating in real time the residual carbohydrates still available during said physical activity comprises a calculation performed continuously of the current glucose oxidation rate calculated as the current heart rate using a linear relation and wherein a value of required carbohydrates for performing the physical activity is continuously calculated by multiplying the current glucose oxidation rate by the % CHO at the current time and wherein the amount of required carbohydrates for the physical activity is updated by accumulating the value of required carbohydrates calculated at a previous time;
calculating of patient specific reference curves for a percentage carbohydrates consumption (% CHO);
scheduling a training session;
estimating the amount of carbohydrates (CHO) to be eaten before said physical activity;
updating in real time the residual carbohydrates still available during said physical activity; and
calculating the amount of carbohydrates to be restored after said physical activity;a chest strap detecting a heart rate of a patient and linked with the processor for introducing of patient and therapy specific parameters; a control and input panel linked with the processor for inputting patient and therapy specific parameters; data memory linked to the processor storing the patient and therapy specific parameters and a history of various sessions; a power supply linked with the apparatus; a display linked with the processor for displaying calculated values, patient and therapy parameters, current status and alarms in case of critical conditions; a PC connection linked with the processor for communicating with an external device; memory interfaces linked with the processor for communicating with an external device; output peripherals including LEDs and a beeper linked with the processor providing an output response. - View Dependent Claims (16)
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17. A method for preventing hypoglycaemia in a DP-1 during physical activity, comprising the following steps:
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providing a processing unit including memory that stores a program code that performs calculations and stores parameters of a process, the process comprising the steps of; defining of working constants and standard parameters; introducing of patient and therapy specific parameters; calculating of patient specific reference curves for a percentage carbohydrates consumption (% CHO); scheduling a training session; estimating the amount of carbohydrates (CHO) to be eaten before said physical activity; updating in real time the residual carbohydrates still available during said physical activity; and calculating the amount of carbohydrates to be restored after said physical activity wherein; said step of introducing of patient and therapy specific parameters comprises the value of glucose oxidation rate approximated with a linear relationship characterized by a slope (BGm) and intercept (BGq), as a carbohydrates consumption (grams/minutes) in function of the heart rate (beats/minutes) and said step of updating in real time the residual carbohydrates still available during said physical activity comprises a calculation performed continuously of the current glucose oxidation rate calculated as the current heart rate using a linear relation and wherein a value of required carbohydrates for performing the physical activity is continuously calculated by multiplying the current glucose oxidation rate by the % CHO at the current time and wherein the amount of required carbohydrates for the physical activity is updated by accumulating the value of required carbohydrates calculated at a previous time and wherein said step of introducing of patient and therapy specific parameters further comprises the following values;
age;
weight;
sex; and
extra cellular fluid (ECF), wherein said value for the (ECF) when not available it can be approximated to (in Litres) 27% of the weight for men, and 22.5% of the weight for women.
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18. A method for preventing hypoglycaemia in a DP-1 during physical activity, comprising the following steps:
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providing a processing unit including memory that stores a program code that performs calculations and stores parameters of a process, the process comprising the steps of; defining of working constants and standard parameters; introducing of patient and therapy specific parameters; calculating of patient specific reference curves for a percentage carbohydrates consumption (% CHO); scheduling a training session; estimating the amount of carbohydrates (CHO) to be eaten before said physical activity; updating in real time the residual carbohydrates still available during said physical activity; and calculating the amount of carbohydrates to be restored after said physical activity wherein; said step of introducing of patient and therapy specific parameters comprises the value of glucose oxidation rate approximated with a linear relationship characterized by a slope (BGm) and intercept (BGq), as a carbohydrates consumption (grams/minutes) in function of the heart rate (beats/minutes) and said step of updating in real time the residual carbohydrates still available during said physical activity comprises a calculation performed continuously of the current glucose oxidation rate calculated as the current heart rate using a linear relation and wherein a value of required carbohydrates for performing the physical activity is continuously calculated by multiplying the current glucose oxidation rate by the % CHO at the current time and wherein the amount of required carbohydrates for the physical activity is updated by accumulating the value of required carbohydrates calculated at a previous time wherein said step of defining the working constants and standard parameters comprises the steps of; defining the number of hours of contribution of dinner insulin; defining the relationship between effective insulinemy and percentage carbohydrates defining the standard sensibility; defining a reference glycemic curve; defining the type-specific insulin curves; and defining a type-specific standard insulin dose and wherein said standard sensibility is set as 4.836.
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Specification