Devices and systems for thrombus treatment

• US 9,204,887 B2
• Filed: 03/13/2013
• Issued: 12/08/2015
• Est. Priority Date: 08/14/2012
• Status: Active Grant

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Cully, Edward H., Friedman, Nathan L., Zacharias, Eric H.
• Primary Examiner(s): Manahan, Todd
• Assistant Examiner(s): Lewis, Casey B
• Application Number:
  US13/802,428
• Publication Number:
  US 20140052103A1
• Time in Patent Office: 1,000 Days
• Field of Search: 606/110, 606/114, 606/127, 606/128, 606/159
• US Class Current: 1/1
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 2017/22069 Immobilising; Stabilising
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/320004 abrasive
• CPC Class Codes: A61B 2017/320716 comprising means for preventing embolism by dislodged material
• CPC Class Codes: A61B 2017/320733 with a flexible cutting or scraping element, e.g. with a whip-like distal filament member
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00

Abstract

A thrombus treatment device includes a support wire, a body frame portion that is disposed about an axis defined by the support wire, one or more tethers that each have a first end and a second end, and a filter element extending from the body frame portion. Each of the one or more tethers is attached at its first end to the body frame portion, and at its second end to a collar that couples the second end of each of the multiple tethers to the support wire. When the collar is positioned substantially within a region interior of the body frame portion, a rotational actuation of the support wire causes a swiveling motion of the one or more tethers.

Claims

1. A thrombus treatment device, comprising:

a support tube defining a longitudinal axis;

a body frame portion that is disposed about the longitudinal axis defined by the support tube, the body frame portion including a proximal end and a distal end;

a filter portion that extends from the distal end of the body frame portion; and

multiple tethers each having a first end and a second end, wherein the first end of each of the multiple tethers extends out a proximal end of the support tube, the tethers extending through a lumen of the support tube and out a distal end of the support tube and engaging the body frame portion near the distal end of the body frame portion and extending to the proximal end of the body frame portion, the second end of each of the multiple tethers being attached to the body frame portion near the proximal end of the body frame portion, wherein each tether of the multiple tethers forms a loop around the body frame portion near the proximal end of the body frame portion.

2. The thrombus treatment device of claim 1, wherein a longitudinal length of the body frame portion is at least three times as long as an outer diameter of the body frame portion.

3. The thrombus treatment device of claim 1, wherein a longitudinal length of the body frame portion is at least four times as long as an outer diameter of the body frame portion.

4. The thrombus treatment device of claim 1, wherein a longitudinal length of the body frame portion is at least five times as long as an outer diameter of the body frame portion.

5. The thrombus treatment device of claim 1, wherein a longitudinal length of the filter portion is less than or equal to one-half of the longitudinal length of the body frame portion.

6. The thrombus treatment device of claim 1, wherein one or more tethers are comprised of nitinol.

7. The thrombus treatment device of claim 1, wherein one or more tethers are comprised of a polymeric material.

8. The thrombus treatment device of claim 1, wherein the tethers extend from the distal end of the support tube near a central collar that is coupled thereto.

9. The thrombus treatment device of claim 1, wherein the filter portion does not substantially overlap the body frame portion.

10. The thrombus treatment device of claim 1, wherein the body frame portion defines a plurality of open-faced cells arranged in at least three rows along a longitudinal length of the body frame portion, and wherein the filter portion overlaps the body frame portion by up to one row of the at least three rows and does not overlap a remaining body frame portion.

11. The thrombus treatment device of claim 10, wherein the body frame portion defines from three to ten rows of open-faced cells along the longitudinal length of the body frame portion.

12. The thrombus treatment device of claim 1, wherein the filter portion overlaps 20% or less of a longitudinal length of the body frame portion.

13. The thrombus treatment device of claim 1, wherein a proximally directed force applied to the first end of each of the multiple tethers causes the distal end of the body frame portion and the proximal end of the body frame portion to collapse radially toward the longitudinal axis defined by the support tube.

14. A thrombus treatment device, comprising:

a support tube defining a longitudinal axis;

a body frame portion that is disposed about the longitudinal axis defined by the support tube, the body frame portion including a proximal end and a distal end;

a filter portion that extends from the distal end of the body frame portion; and

multiple tethers each having a first end and a second end, wherein the first end of each of the multiple tethers extends out a proximal end of the support tube, the tethers extending through a lumen of the support tube and out a distal end of the support tube and engaging the body frame portion near the distal end of the body frame portion and extending to the proximal end of the body frame portion, the second end of each of the multiple tethers being attached to the body frame portion near the proximal end of the body frame portion, wherein the multiple tethers collectively form a loop around the body frame portion near the proximal end of the body frame portion.

15. The thrombus treatment device of claim 14, wherein a proximally directed force applied to the first end of each of the multiple tethers causes the distal end of the body frame portion and the proximal end of the body frame portion to collapse radially toward the longitudinal axis defined by the support tube.

16. The thrombus treatment device of claim 14, wherein a longitudinal length of the body frame portion is at least three times as long as an outer diameter of the body frame portion.

17. The thrombus treatment device of claim 14, wherein a longitudinal length of the body frame portion is at least four times as long as an outer diameter of the body frame portion.

18. The thrombus treatment device of claim 14, wherein a longitudinal length of the body frame portion is at least five times as long as an outer diameter of the body frame portion.

19. The thrombus treatment device of claim 14, wherein a longitudinal length of the filter portion is less than or equal to one-half of the longitudinal length of the body frame portion.

20. The thrombus treatment device of claim 14, wherein one or more tethers are comprised of nitinol.

21. The thrombus treatment device of claim 14, wherein one or more tethers are comprised of a polymeric material.

22. The thrombus treatment device of claim 14, wherein the tethers extend from the distal end of the support tube near a central collar that is coupled thereto.

23. The thrombus treatment device of claim 14, wherein the filter portion does not substantially overlap the body frame portion.

24. The thrombus treatment device of claim 14, wherein the body frame portion defines a plurality of open-faced cells arranged in at least three rows along a longitudinal length of the body frame portion, and wherein the filter portion overlaps the body frame portion by up to one row of the at least three rows and does not overlap a remaining body frame portion.

25. The thrombus treatment device of claim 24, wherein the body frame portion defines from three to ten rows of open-faced cells along the longitudinal length of the body frame portion.

26. The thrombus treatment device of claim 14, wherein the filter portion overlaps 20% or less of a longitudinal length of the body frame portion.