Nasal devices
First Claim
Patent Images
1. A nasal delivery device for delivering a substance to a nasal airway of a subject, comprising:
- a nosepiece adapted for fitting to a nasal cavity of a subject, the nosepiece including a first delivery outlet comprising a nozzle from which a liquid spray of the substance is delivered to the nasal airway of the subject, and a second delivery outlet through which a flow of gas, separate from an exhalation breath of the subject, is delivered to the nasal airway of the subject, wherein the second delivery outlet is separate from the nozzle, and the nozzle and the second delivery outlet are disposed such that the flow of gas that is delivered through the second delivery outlet first interacts with the liquid spray as delivered from the nozzle downstream of the nozzle;
a delivery unit for delivering the substance through the first delivery outlet of the nozzle;
a gas supply unit for supplying the flow of gas through the second delivery outlet;
a mouthpiece unit through which the subject in use exhales to cause closure of an oropharyngeal velum of the subject; and
an actuation mechanism for actuating the delivery unit and the gas supply unit on exhalation by the subject.
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Accused Products
Abstract
A nasal delivery device for and a method of delivering a substance, in particular one of a liquid, as a suspension or solution, or a powder containing a medicament, especially systemic or topical pharmaceuticals, or a vaccine to the nasal airway of a subject.
98 Citations
14 Claims
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1. A nasal delivery device for delivering a substance to a nasal airway of a subject, comprising:
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a nosepiece adapted for fitting to a nasal cavity of a subject, the nosepiece including a first delivery outlet comprising a nozzle from which a liquid spray of the substance is delivered to the nasal airway of the subject, and a second delivery outlet through which a flow of gas, separate from an exhalation breath of the subject, is delivered to the nasal airway of the subject, wherein the second delivery outlet is separate from the nozzle, and the nozzle and the second delivery outlet are disposed such that the flow of gas that is delivered through the second delivery outlet first interacts with the liquid spray as delivered from the nozzle downstream of the nozzle; a delivery unit for delivering the substance through the first delivery outlet of the nozzle; a gas supply unit for supplying the flow of gas through the second delivery outlet; a mouthpiece unit through which the subject in use exhales to cause closure of an oropharyngeal velum of the subject; and an actuation mechanism for actuating the delivery unit and the gas supply unit on exhalation by the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification