Neurostimulation system

• US 9,205,259 B2
• Filed: 02/22/2012
• Issued: 12/08/2015
• Est. Priority Date: 09/08/2004
• Status: Active Grant

• Current Assignee: TC1 LLC (Abbott Laboratories Incorporated), Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Original Assignee: Spinal Modulation, Inc. (Abbott Laboratories Incorporated), Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Inventors: Kim, Daniel H., Imran, Mir A.
• Primary Examiner(s): Porter, Jr., Allen
• Application Number:
  US13/402,786
• Publication Number:
  US 20120197370A1
• Time in Patent Office: 1,385 Days
• Field of Search: 607115-118, 607/2, 607/3, 607/33, 607/46, 607/61, 607/62, 600/372, 600/373, 600/377, 600/378
• US Class Current: 1/1
• CPC Class Codes: A61M 2210/1003 Spinal column
• CPC Class Codes: A61M 25/06 Body-piercing guide needles or the like
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/0568 with drug delivery
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36139 with automatic adjustment
• CPC Class Codes: A61N 1/36171 Frequency

Abstract

Some embodiments of the present invention provide neurostimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia. Some other embodiments of the present invention provide neurostimulation systems adapted for selective neurostimulation of one or more nerve root ganglia as well as techniques for applying neurostimulation to the spinal cord. Still other embodiments of the present invention provide stimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia in combination with a pharmacological agent.

Claims

1. A system for stimulating a dorsal root ganglion within a body, the system comprising:

a lead comprising an elongate body having a plurality of electrodes disposed thereon, wherein the lead is configured for positioning at least one of the plurality of electrodes within a distance of the dorsal root ganglion so as to provide selective stimulation of the dorsal root ganglion; and

an implantable pulse generator connectable with the lead so as to provide stimulation energy to a selection of the plurality of electrodes which provides stimulation to the dorsal root ganglion without intervening vertebral bone while selectively stimulating the dorsal root ganglion.

2. A system as in claim 1, wherein the plurality of electrodes are individually energizeable.

3. A system as in claim 1, wherein one or more of the plurality of electrodes receive no stimulation energy.

4. A system as in claim 1, wherein one or more of the plurality of electrodes receive less stimulation energy than others.

5. A system as in claim 1, wherein the lead is shaped for advancement through an epidural space of the body.

6. A system as in claim 1, wherein the lead is shaped for advancement through a foramen.

7. A system as in claim 1, wherein the plurality of electrodes comprises at least one pair of electrodes in a bipolar arrangement.

8. A system as in claim 1, wherein the plurality of electrodes comprises more than one pair of electrodes in a bipolar arrangement.

9. A system as in claim 1, wherein the lead is configured for positioning the selection of the plurality of electrodes outside of the dura of the dorsal root ganglion while the at least one of the plurality of electrodes is positioned within the distance of the dorsal root ganglion.

10. A system as in claim 1, wherein the implantable pulse generator provides stimulation so that selectively stimulating the dorsal root ganglion comprises stimulating sensory nerves without stimulating motor nerves.

11. A system as in claim 1, wherein the lead is shaped for advancement laterally toward the dorsal root ganglion.