Neural stimulation system providing auto adjustment of stimulus output as a function of sensed impedance

• US 9,205,263 B2
• Filed: 05/19/2010
• Issued: 12/08/2015
• Est. Priority Date: 02/12/2002
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: King, John D. H., Thacker, James R.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Ghand, Jennifer
• Application Number:
  US12/783,187
• Publication Number:
  US 20100262209A1
• Time in Patent Office: 2,029 Days
• Field of Search: 600/547, 600/594, 607/43, 607/46, 607/62
• US Class Current: 1/1
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36139 with automatic adjustment
• CPC Class Codes: A61N 1/3615 Intensity

Abstract

A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.

Claims

1. A method of providing therapy to a patient using a neurostimulation system that stores electrical parameter measurements in correspondence with different postural events, comprising:

applying a stimulation energy output from the neurostimulation system to the patient;

measuring an electrical parameter in the patient;

comparing the measured electrical parameter to the stored electrical parameter measurements;

determining if a postural event in the patient has occurred based on the comparison; and

adjusting the applied stimulation energy output if the postural event has been determined to have occurred.

2. The method of claim 1, wherein the neurostimulation system stores stimulation energy output adjustments correlated respectively to the stored electrical parameter measurements are stored in the neurostimulation system, and the method further comprises comparing the measured electrical parameter to the stored electrical parameter measurements, wherein the applied stimulation energy output is adjusted based on the comparison.

3. The method of claim 2, wherein the correlated stimulation energy output adjustments and electrical parameter measurements are stored in a look-up table.

4. The method of claim 1, wherein the measured electrical parameter is an impedance change.

5. The method of claim 4, wherein the impedance change is a characteristic impedance waveform morphology.

6. The method of claim 1, wherein the postural event is one of sitting to lying, standing to lying, sitting to standing, twisting the torso to one or the other side, standing to sitting, and running.

7. The method of claim 1, wherein stimulation energy output adjustment comprises adjusting one or more of a pulse amplitude, pulse width, and pulse frequency of the applied stimulation energy output.

8. The method of claim 1, further comprising applying an electrical signal in the patient, wherein the electrical parameter is measured in response to the application of the electrical signal.

9. A method of providing therapy to a patient using a neurostimulation system, comprising:

applying a stimulation energy output from the neurostimulation system to the patient;

measuring an electrical parameter in the patient;

determining if a postural event in the patient has occurred based on the measured electrical parameter, wherein the postural event is one of sitting to lying, standing to lying, sitting to standing, twisting the torso to one or the other side, standing to sitting, and running; and

adjusting the applied stimulation energy output if the postural event has been determined to have occurred.

10. The method of claim 9, wherein the measured electrical parameter is an impedance change.

11. The method of claim 10, wherein the impedance change is a characteristic impedance waveform morphology.

12. The method of claim 9, wherein stimulation energy output adjustment comprises adjusting one or more of a pulse amplitude, pulse width, and pulse frequency of the applied stimulation energy output.

13. The method of claim 9, further comprising applying an electrical signal in the patient, wherein the electrical parameter is measured in response to the application of the electrical signal.