Tissue thickness compensator comprising a plurality of medicaments

• US 9,211,120 B2
• Filed: 03/28/2012
• Issued: 12/15/2015
• Est. Priority Date: 04/29/2011
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Scheib, Charles J., Shelton, Frederick E. IV
• Primary Examiner(s): Smith, Scott A.
• Application Number:
  US13/433,129
• Publication Number:
  US 20130256367A1
• Time in Patent Office: 1,357 Days
• Field of Search: 227/19, 227/175.1, 227/176.1, 227/178.1, 227/180.1, 606/139, 606/153, 606/219
• US Class Current: 1/1
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0643 with separate closing member, e.g. for interlocking with staple
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 17/068 Surgical staplers , e.g. containing multiple staples or clampsstaplers containing only one staple A61B17/10; magazines or containers for staples A61B17/105; for performing anastomosis A61B17/115; staplers in general B25C5/00
• CPC Class Codes: A61B 17/072 for applying a row of staples in a single action , e.g. the staples being applied simultaneously
• CPC Class Codes: A61B 17/07207 the staples being applied sequentially
• CPC Class Codes: A61B 17/07292 Reinforcements for staple line, e.g. pledgets
• CPC Class Codes: A61B 17/1155 Circular staplers comprising a plurality of staples
• CPC Class Codes: A61B 17/2909 Handles
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/0053 Loading magazines or sutures into applying tools
• CPC Class Codes: A61B 2017/00561 creating a vacuum
• CPC Class Codes: A61B 2017/00818 Treatment of the gastro-intestinal system
• CPC Class Codes: A61B 2017/00862 elastic or resilient
• CPC Class Codes: A61B 2017/00884 enhancing wound closure
• CPC Class Codes: A61B 2017/00889 antimicrobial, disinfectant
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/00942 : hydrophilic
• CPC Class Codes: A61B 2017/00951 : adhesive
• CPC Class Codes: A61B 2017/07228 : Arrangement of the staples
• CPC Class Codes: A61B 2017/07235 : containing different staples, e.g. staples of different shapes, sizes or materials
• CPC Class Codes: A61B 2017/07242 : achieving different staple heights during the same shot, e.g. using an anvil anvil having different heights or staples of different sizes
• CPC Class Codes: A61B 2017/07264 : characterised by its staple forming cavities, e.g. geometry or material
• CPC Class Codes: A61B 2017/07271 : characterised by its cartridge
• CPC Class Codes: A61B 2017/07278 : characterised by its sled or its staple holder
• CPC Class Codes: A61B 2017/07285 : characterised by its cutter
• CPC Class Codes: A61B 2017/2908 : Multiple segments connected by articulations
• CPC Class Codes: A61B 2017/2919 : details of linkages or pivot points
• CPC Class Codes: A61B 2017/2923 : Toothed members, e.g. rack and pinion
• CPC Class Codes: A61B 2017/2927 : the angular position of the head being adjustable with respect to the shaft
• CPC Class Codes: A61B 2017/2933 : camming or guiding means
• CPC Class Codes: A61B 2017/2936 : Pins in guiding slots
• CPC Class Codes: A61B 2017/2946 : Locking means
• CPC Class Codes: A61B 2017/320052 : Guides for cutting instruments
• CPC Class Codes: A61B 2090/0811 : for the position of a particular part of an instrument with respect to the rest of the instrument, e.g. position of the anvil of a stapling instrument
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 90/92 : coded with colour
• CPC Class Codes: A61L 17/005 : containing a biologically active substance, e.g. a medicament or a biocide
• CPC Class Codes: A61L 2300/102 : Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/232 : Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
• CPC Class Codes: A61L 2300/45 : Mixtures of two or more drugs, e.g. synergistic mixtures
• CPC Class Codes: F04C 2270/0421 : Controlled or regulated
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

In various embodiments, a compensator can comprise a compensator body comprising a plurality of first packets and a plurality of second packets wherein, in at least one embodiment, each second packet is positioned intermediate two or more first packets. The compensator can further comprise a first medicament positioned within each first packet and a second medicament positioned within each second packet, wherein the first medicament is different than the second medicament.

Claims

1. A compensator attachable to an anvil of a fastening instrument, wherein the anvil includes a forming surface, and wherein said compensator comprises:

a compressible compensator body, comprising;

a plurality of first packets;

a plurality of second packets, wherein each said second packet is positioned intermediate two or more said first packets;

a first medicament enclosed within each said first packet until each said first packet is opened;

a second medicament enclosed within each said second packet until each said second packet is opened, wherein said first medicament is different than said second medicament; and

an attachment portion configured to be attached to the anvil.

2. The compensator of claim 1, wherein said first medicament comprises a first powder and said second medicament comprises a second powder.

3. The compensator of claim 1, wherein said first medicament comprises alginate and said second medicament comprises calcium.

4. The compensator of claim 1, wherein said compensator body comprises a longitudinal axis, and wherein said first packets and said second packets are arranged in an alternating arrangement along said longitudinal axis.

5. The compensator of claim 1, wherein said first packets and said second packets are arranged in an alternating arrangement.

6. The compensator of claim 1, wherein said first medicament can comprise non-woven oxidized regenerated cellulose.

7. A stapling assembly for use with a stapler, said stapling assembly comprising:

an anvil, comprising;

a plurality of forming surfaces; and

a slot configured to receive a cutting member therein;

a compensator attached to said anvil, wherein said compensator comprises a plurality of first packets aligned with said slot and a plurality of second packets aligned with said slot, and wherein said first packets and said second packets are configured to be incised by the cutting member;

a first medicament enclosed within each said first packet until each said first packet is incised by the cutting member; and

a second medicament enclosed within each said second packet until each said second packet is incised by the cutting member, wherein said first medicament is different than said second medicament.

8. The stapling assembly of claim 7, wherein said slot defines a path for the cutting member, and wherein said first packets and said second packets extend in a direction which is transverse to said path.

9. The stapling assembly of claim 7, wherein said compensator comprises and attachment portion configured to fit within said slot, and wherein said attachment portion is configured to be incised by the cutting member.

10. The stapling assembly of claim 7, wherein said first medicament comprises a first powder and said second medicament comprises a second powder.

11. The stapling assembly of claim 7, wherein said first medicament comprises alginate and said second medicament comprises calcium.

12. The stapling assembly of claim 7, wherein said first packets and said second packets are arranged in an alternating arrangement along said slot.

13. A stapling assembly for use with a stapler, said stapling assembly comprising:

an anvil, comprising;

a plurality of forming surfaces; and

a longitudinal slot;

a cutting member configured to be moved within said slot;

a compensator attached to said anvil, wherein said compensator comprises a plurality of first lateral cavities extending laterally relative to said slot and a plurality of second lateral cavities extending laterally relative to said slot, and wherein said cutting member is configured to incise said first lateral cavities and said second lateral cavities;

a first medicament enclosed within each said first lateral cavity, wherein said first medicament is configured to be released from each said first lateral cavity when said first lateral cavity is incised by said cutting member; and

a second medicament enclosed within each said second lateral cavity, wherein said first medicament is different than said second medicament, and wherein said second medicament is configured to be released from each said second lateral cavity when said second lateral cavity is incised by said cutting member.

14. The stapling assembly of claim 13, wherein said compensator comprises an attachment portion configured to fit within said longitudinal slot, and wherein said cutting member is configured to incise said attachment portion.

15. The stapling assembly of claim 13, wherein said first medicament comprises a first powder and said second medicament comprises a second powder.

16. The stapling assembly of claim 13, wherein said first medicament comprises alginate and said second medicament comprises calcium.

17. The stapling assembly of claim 13, wherein said first lateral cavities and said second lateral cavities are arranged in an alternating arrangement along said longitudinal slot.

18. The stapling assembly of claim 13, wherein said longitudinal slot defines a longitudinal axis, and wherein said first lateral cavities and said second lateral cavities each define a lateral axis perpendicular to said longitudinal axis.

19. A staple cartridge assembly for use with a surgical stapler, said staple cartridge assembly comprising:

a cartridge body;

a plurality of staple cavities;

a plurality of staples removably stored within said staple cavities; and

a layer, comprising;

a plurality of first packets;

a plurality of second packets, wherein each said second packet is positioned intermediate two or more said first packets;

a first medicament enclosed within each said first packet until each said first packet is opened; and

a second medicament enclosed within each said second packet until each said second packet is opened, wherein said first medicament is different than said second medicament.

20. The staple cartridge assembly of claim 19, further comprising an anvil.