Adhesive structure with stiff protrusions on adhesive surface

• US 9,211,176 B2
• Filed: 03/15/2013
• Issued: 12/15/2015
• Est. Priority Date: 08/30/2010
• Status: Active Grant

• Current Assignee: Endo-Surgery, Inc., Agency For Science Technology and Research (Government of Singapore), Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Original Assignee: Agency For Science Technology and Research (Government of Singapore), Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Natarajan, Sriram, Hammer, Joseph, Cooper, Kevin, Vyakarnam, Murty, Low, Hong Yee, Rodriguez, Isabel, Lim, Chee Tiong, Ho, Audrey Yoke Yee
• Primary Examiner(s): Gupta, Yogendra
• Assistant Examiner(s): STEWART, KIMBERLY ANN
• Application Number:
  US13/841,561
• Publication Number:
  US 20130206330A1
• Time in Patent Office: 1,005 Days
• Field of Search: 264/317, 264/41
• US Class Current: 1/1
• CPC Class Codes: A61B 2017/00871 polymeric
• CPC Class Codes: A61B 2017/00938 hydrophobic
• CPC Class Codes: A61B 2017/00942 hydrophilic
• CPC Class Codes: A61B 2017/00951 adhesive
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61L 31/048 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: B29C 33/52 soluble or fusible in particular used in injection moulding B29C45/4457
• CPC Class Codes: C08L 23/12 Polypropene
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence
• CPC Class Codes: C09J 2301/206 the adhesive layer comprising non-adhesive protrusions
• CPC Class Codes: C09J 2400/263 in the substrate
• CPC Class Codes: C09J 7/21 Paper; Textile fabrics
• CPC Class Codes: C09J 7/30 characterised by the adhesive composition

Abstract

A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young'"'"'s modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.

Claims

1. A method of forming a laminate of a surgical mesh having first and second surfaces, and an adhesive structure having adhesive and non-adhesive surfaces, comprising:

a) providing a first solvent-dissolvable mold including indentations;

b) providing a first meltable polymer having a Young'"'"'s modulus of greater than 17 MPa to the first mold under conditions sufficient to permit filling the indentations of the first mold by the first polymer, said first polymer being non-dissolvable by the solvent;

c) treating the first mold and first polymer of step b) to an extent sufficient to solidify the first polymer;

d) laminating a surgical mesh, also non-dissolvable by said solvent, to an exposed surface of said first meltable polymer at the top of said first mold; and

e) exposing the first mold, first polymer and surgical mesh to the solvent under mold-dissolving conditions to dissolve said first mold.

2. The method of claim 1, further comprising

f) providing a second solvent-dissolvable mold including indentations;

g) providing a second meltable polymer having a Young'"'"'s modulus of greater than 17 MPa to the second mold under conditions sufficient to permit filling the indentations of the second mold by the second polymer, said second polymer being non-dissolvable by the solvent;

h) treating the second mold and second polymer of step g) to an extent sufficient to solidify the second polymer;

i) laminating an exposed surface of said second meltable polymer at the top of said second mold to the surgical mesh; and

j) exposing both said first and second molds, first and second polymers and the surgical mesh to the solvent under mold-dissolving conditions.