Selective resonance of bodily agents

• US 9,211,332 B2
• Filed: 04/27/2012
• Issued: 12/15/2015
• Est. Priority Date: 07/21/2005
• Status: Active Grant

• Current Assignee: Enterprise Science Fund, LLC (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Jung, Edward K. Y., Leuthardt, Eric C., Myhrvold, Nathan P., Wood, Lowell L. Jr.
• Primary Examiner(s): NEGIN, RUSSELL SCOTT
• Application Number:
  US13/457,993
• Publication Number:
  US 20120215156A1
• Time in Patent Office: 1,327 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61K 41/0004 Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
• CPC Class Codes: A61M 37/0092 using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
• CPC Class Codes: A61N 5/00 Radiation therapy ultrasound therapy A61N7/00; devices or apparatus applicable to both therapy and diagnosis A61B6/00
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent
• CPC Class Codes: G16B 15/00 ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
• CPC Class Codes: G16B 40/00 ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
• CPC Class Codes: G16B 5/00 ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Abstract

Chemical compositions may be selectively or preferentially excited by the application of scores comprising a series of energy inputs.

Claims

1. A method, comprising

identifying an agent in a body that modulates a biological activity in the body;

selecting a set of noncontinuous differing energy inputs specific to the agent, wherein the set of differing energy inputs selectively resonates a plurality of resonant structures in the agent, including resonating at least one bond; and

directing the set of differing energy inputs towards the agent while it is in the body,

wherein directing the set of differing energy inputs towards the agent changes its modulation of the biological activity in the body.

2. The method of claim 1, wherein directing the set of differing energy inputs towards the agent initiates a therapeutic effect in the body.

3. The method of claim 1, wherein directing the set of differing energy inputs towards the agent terminates a therapeutic effect in the body.

4. The method of claim 1, wherein directing the set of differing energy inputs towards the agent destroys the agent.

5. The method of claim 1, wherein the agent is selected from the group consisting of analgesics, antacids, antianxiety drugs, antiarrhythmics, anticoagulants, anticonvulsants, antidepressants, antidiarrheals, antiemetics, antifungals, antihistamines, antihypertensives, anti-inflammatories, antiplatelet drugs, antipsychotics, antipyretics, antivirals, barbiturates, beta-blockers, bronchodilators, chemotherapy drugs, corticosteroids, cough suppressants, cytotoxics, decongestants, diuretics, expectorants, hormones, hypoglycemics, immunosuppressives, laxatives, muscle relaxants, sedatives, sex hormones, sleeping drugs, tranquilizers, and vitamins.

6. The method of claim 5, wherein the agent is an antiplatelet drug.

7. The method of claim 6, wherein directing the set of differing energy inputs towards the agent destroys the agent.

8. The method of claim 7, wherein the agent is clopidogrel.

9. The method of claim 7, further comprising performing an incision on the body.

10. The method of claim 1, wherein the body is alive.

11. The method of claim 1, wherein the body is human.

12. The method of claim 1, wherein the agent is present in blood.

13. The method of claim 1, further comprising monitoring the body for activity of the agent.

14. The method of claim 1, further comprising monitoring the body for quantity of the agent.

15. The method of claim 1, wherein the agent comprises a functional group selected to be responsive to the set of differing energy inputs.

16. The method of claim 1, further comprising modifying the agent to add a functional group selected to be responsive to the set of differing energy inputs.

17. The method of claim 1, wherein the agent is selected from the group consisting of blood clotting factors, sugars, lipids, lipoproteins, vitamins, minerals, hormones, enzymes, antibodies, and proteins.

18. The method of claim 17, wherein the agent is a blood clotting factor selected from the group consisting of prekallikrein, high molecular weight kininogen, clotting factors I-XIII, von Willebrand factor, protein C, protein S, thrombomodulin, and antithrombin III.

19. The method of claim 17, wherein the agent is a sugar selected from the group consisting of glucose, fructose, sucrose, galactose, mannose, glycerol, and glucuronate.

20. The method of claim 17, wherein the agent is a lipid or lipoprotein selected from the group consisting of cholesterol, triglicerides, triacylglycerols, chylomicrons, very low density lipoproteins, low density lipoproteins, intermediate density lipoproteins, and high density lipoproteins.

21. The method of claim 17, wherein the agent is a hormone selected from the group consisting of adrenalin, adrenocorticotropic hormone, aldosteron, calcitonin, cortisol, insulin, gastrin, glucagon, glucocorticoids, thyroid hormone, gastrin, secretin, cholecystokinin, somatostatin, neuropeptide Y, other hormones of the gut, thyrotropin-releasing hormone, gonadotropin-releasing hormone, growth hormone-releasing hormone, ghrelin, corticotrophin-releasing hormone, somatostatin, dopamine, antidiuretic hormone, oxytocin, other hormones of the hypothalamus, renin, erythropoietin, calcitrol, other hormones of the kidney, insulin-like growth factor-1, angiotensinogen, thrombopoietin, other hormones of the liver, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, prolactin, growth hormone, adrenocorticotropic hormone, antidiuretic hormone, other hormones of the pituitary, estrogen, testosterone, progesterone, anabolic steroids, other reproductive hormones, melanocyte-stimulating hormone, parathyroid hormone, melatonin, prolactin, and thyroid hormones.

22. The method of claim 17, wherein the agent is an enzyme selected from the group consisting of creatine kinase, lactate dehydrogenase, troponin, other cardiac enzymes, aspartate transaminase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyltranspeptidase, and other liver enzymes.

23. The method of claim 17, wherein the agent is an antibody to an autoimmune disorders selected from the group consisting of acute transverse myelitis, allergic (Henoch-Schö

nlein) purpura, alopecia areata, aplastic anemia, brachial neuritis, bullous pemphigoid, dermatitis herpetiformis, polymyositis, dermatomyositis, Eaton-Lambert syndrome, eosinophilic fasciitis, Goodpasture'"'"'s syndrome, Guillain-Barré

syndrome, hemolytic anemia, hepatitis, mixed connective tissue disease, multiple sclerosis, myasthenia gravis, pemphigus, peripheral ulcerative keratitis, polyglandular deficiency syndrome, relapsing polychondritis, rheumatoid arthritis, scleroderma, Sjö

gren'"'"'s syndrome, and system lupus erythematosus.

24. The method of claim 17, wherein the agent is an antibody to a transplanted material.

25. The method of claim 24, wherein the transplanted material is selected from the group consisting of organs, stem cells, and device implants.

26. The method of claim 17, wherein the agent is a protein selected from the group consisting of albumins, globulins, fibrinogens, and hemoglobins.