Fluid processing and control
First Claim
1. A method for controlling fluid flow in a fluid control and processing system, the system comprising(1) a housing having a plurality of chambers;
- and(2) a valve body received in the housing, the valve body comprising a single fluid processing region continuously coupled fluidicly to a single fluid displacement region, wherein the fluid processing region is contained within a disk portion of the valve body, and the fluid displacement region is contained substantially within a tubular portion of the valve body, the fluid displacement region being depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region, the valve body including a plurality of external ports, the fluid processing region being fluidicly coupled with at least two of the external ports, the fluid displacement region being fluidicly coupled with at least one of the external ports, and the valve body being adjustable relative to a plurality of chamber ports to allow the external ports to be placed selectively in fluidic communication with the plurality of chambers, wherein at least one of the plurality of chambers is a processing chamber different from said fluid processing region, the processing chamber including a first chamber port and a second chamber port for selectively communicating with at least one of the external ports of the valve body, wherein the processing chamber contains a fluid processing material being (a) an enrichment material that captures a target from the fluid sample, or (b) a trapping material that traps unwanted material from the fluid sample,the method comprising;
adjusting the valve body to allow the external ports to be placed selectively in fluidic communication with the plurality of chambers.
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Abstract
A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers. One or more of the chambers may be a processing chamber which includes two ports configured to selectively engage the at least one external port of the body, and a fluid processing material such as an enrichment material or a depletion material. In some embodiments, one or more chambers may include a separation channel, and an electric field may be applied across the separation channel.
42 Citations
27 Claims
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1. A method for controlling fluid flow in a fluid control and processing system, the system comprising
(1) a housing having a plurality of chambers; - and
(2) a valve body received in the housing, the valve body comprising a single fluid processing region continuously coupled fluidicly to a single fluid displacement region, wherein the fluid processing region is contained within a disk portion of the valve body, and the fluid displacement region is contained substantially within a tubular portion of the valve body, the fluid displacement region being depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region, the valve body including a plurality of external ports, the fluid processing region being fluidicly coupled with at least two of the external ports, the fluid displacement region being fluidicly coupled with at least one of the external ports, and the valve body being adjustable relative to a plurality of chamber ports to allow the external ports to be placed selectively in fluidic communication with the plurality of chambers, wherein at least one of the plurality of chambers is a processing chamber different from said fluid processing region, the processing chamber including a first chamber port and a second chamber port for selectively communicating with at least one of the external ports of the valve body, wherein the processing chamber contains a fluid processing material being (a) an enrichment material that captures a target from the fluid sample, or (b) a trapping material that traps unwanted material from the fluid sample, the method comprising; adjusting the valve body to allow the external ports to be placed selectively in fluidic communication with the plurality of chambers. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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Specification