Providing iPSCs to a customer
First Claim
Patent Images
1. A method for providing mammalian iPSC-derived differentiated cells to a customer, comprising:
- (a) expanding mammalian iPSCs and stocking the expanded iPSCs in an iPSC bank, wherein the iPSCs are obtained from a plurality of different iPSCs, each of the iPSCs being derived from a sample of mammalian somatic cells obtained from a donor having a disease or condition or genetically predisposed to a disease or condition;
(b) obtaining criteria from a customer for selection of an iPSC based on one or more of of the diseases or conditions suffered by donor or for which the donor is genetically predisposed;
(c) searching a database comprising sample information for each of the plurality of different iPSCs in an iPSC bank, said different iPSCs having genetic material from different donors, said sample information comprising one or more of said criteria;
(d) identifying suitable iPSCs matching the criteria from the customer in said iPSC bank; and
(e) differentiating a part of the iPSCs stocked in step (a) and identified in step (d) to produce the mammalian iPSC-derived differentiated cells; and
(f) providing the mammalian iPSC-derived differentiated cells to the customer.
2 Assignments
0 Petitions
Accused Products
Abstract
The present disclosure features methods relating to conducting a stem cell technology business such as a regenerative medicine business based on induced pluripotent stem cells (iPSCs) and cells differentiated from iPSCs. The present disclosure also provides a database of iPSC-derived cells and methods of using the database for tracking customers and samples, as well as methods for marketing and running the business.
134 Citations
4 Claims
-
1. A method for providing mammalian iPSC-derived differentiated cells to a customer, comprising:
-
(a) expanding mammalian iPSCs and stocking the expanded iPSCs in an iPSC bank, wherein the iPSCs are obtained from a plurality of different iPSCs, each of the iPSCs being derived from a sample of mammalian somatic cells obtained from a donor having a disease or condition or genetically predisposed to a disease or condition; (b) obtaining criteria from a customer for selection of an iPSC based on one or more of of the diseases or conditions suffered by donor or for which the donor is genetically predisposed; (c) searching a database comprising sample information for each of the plurality of different iPSCs in an iPSC bank, said different iPSCs having genetic material from different donors, said sample information comprising one or more of said criteria; (d) identifying suitable iPSCs matching the criteria from the customer in said iPSC bank; and (e) differentiating a part of the iPSCs stocked in step (a) and identified in step (d) to produce the mammalian iPSC-derived differentiated cells; and (f) providing the mammalian iPSC-derived differentiated cells to the customer. - View Dependent Claims (2, 3, 4)
-
Specification