Compact self-contained automated MDI adapters or units for ventilators

• US 9,216,267 B2
• Filed: 10/24/2014
• Issued: 12/22/2015
• Est. Priority Date: 05/18/2010
• Status: Active Grant

• Current Assignee: iDTx Systems, Inc
• Original Assignee: iDTx Systems, Inc
• Inventors: Spandorfer, Michael, Gilbert, Murphy Pearce
• Primary Examiner(s): DOUGLAS, STEVEN O
• Application Number:
  US14/523,403
• Publication Number:
  US 20150040899A1
• Time in Patent Office: 424 Days
• Field of Search: 128/203.14, 128/205.23, 128/202.27, 128/910
• US Class Current: 1/1
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: A61M 15/0003 with means for dispensing more than one drug
• CPC Class Codes: A61M 15/0005 with means for agitating the medicament
• CPC Class Codes: A61M 15/0066 with means for varying the dose size
• CPC Class Codes: A61M 15/008 Electronic counters
• CPC Class Codes: A61M 15/0081 Locking means
• CPC Class Codes: A61M 15/0083 Timers
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/0816 Joints or connectors
• CPC Class Codes: A61M 16/1045 Devices for humidifying or heating the inspired gas by using recovered moisture or heat from the expired gas
• CPC Class Codes: A61M 16/14 by mixing different fluids, one of them being in a liquid phase
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/276 preventing unwanted use
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3561 : local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3569 : sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 : using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/505 : Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/52 : with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/6009 : for matching patient with his treatment, e.g. to improve transfusion security
• CPC Class Codes: A61M 2205/6054 : Magnetic identification systems
• CPC Class Codes: A61M 2205/6072 : Bar codes
• CPC Class Codes: A61M 2205/609 : Biometric patient identification means
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2209/01 : Remote controllers for specific apparatus
• CPC Class Codes: A61M 2230/43 : Composition of exhalation

Abstract

A system for providing automated delivery of medication to a ventilator circuit that extends between a mechanical ventilator and a patient includes a connector that resides in-line with a portion of the ventilator circuit, a portable medication delivery unit attached to the connector, and a control device in communication with the portable delivery unit. The portable delivery unit includes a housing releasably holding at least one metered dose inhaler canister containing medication and an actuator held by the housing and in communication with the canister to direct the canister to release medication to the ventilator circuit for the patient. The control device is configured to control an amount and/or frequency of medication delivery from the canister to the ventilator circuit for a respective patient and to direct the actuator to actuate to deliver the medication from the canister to the ventilator circuit at a defined amount and/or frequency.

Claims

1. A system for providing automated delivery of medication to a ventilator circuit that extends between a mechanical ventilator and a patient, the system comprising:

a connector that resides in-line with a portion of the ventilator circuit;

a portable medication delivery unit attached to the connector, the portable delivery unit comprising;

a housing releasably holding an upper end portion of at least one metered dose inhaler (MDI) canister containing medication such that a major portion of the canister extends outside the housing, wherein the canister includes an outlet nozzle residing below and opposite the upper end portion that is received through an entry port in the connector such that the canister is in fluid communication with the ventilator circuit; and

an actuator held by the housing and in communication with the canister to direct the canister to release medication to the ventilator circuit for the patient, wherein the actuator is disposed adjacent the upper end portion of the canister; and

a control device in communication with the portable delivery unit, the control device configured to control an amount and/or frequency of medication delivery from the canister to the ventilator circuit for a respective patient and to direct the actuator to actuate and deliver the medication from the canister to the ventilator circuit at a defined amount and/or frequency.

2. The system of claim 1, wherein the portable delivery unit is releasably attached to the connector such that the housing is adjacent and/or on the connector with the connector extending completely outside the housing.

3. The system of claim 1, wherein the portable delivery unit is a compact, lightweight device.

4. The system of claim 1, wherein the control device comprises a user interface to allow an operator to input to the control device the amount and/or frequency of medication delivery from the canister to the ventilator circuit for the patient.

5. The system of claim 4, wherein the user interface comprises a manual override control to direct the actuator to actuate to deliver medication from the canister to the ventilator circuit for a respective patient irrespective of the defined amount and/or frequency of medication delivery.

6. The system of claim 1, wherein the control device comprises a display for displaying parameters including the defined amount and/or frequency of medication delivery and an amount of medication remaining in the canister, wherein the control device is configured to dynamically update the displayed parameters.

7. The system of claim 1, wherein the control device is a handheld electronic device.

8. The system of claim 7, wherein the control device is in wireless communication with the delivery unit.

9. The system of claim 1, further comprising a gas flow sensor disposed in the interior of the connector, the gas flow sensor configured to detect a gas flow direction through the connector and communicate the gas flow direction to the control device.

10. The system of claim 9, wherein the control device is configured to direct the actuator to actuate to deliver medication from the canister to the ventilator circuit when the gas flow direction in the connector is from the ventilator to the patient based on data detected by the gas flow sensor.

11. The system of claim 9, wherein the gas flow sensor is configured to detect at least one gas flow characteristic of gas flowing through the connector and to communicate the detected at least one gas flow characteristic to the control device, and wherein the control device is configured to adjust the amount and/or frequency of medication delivery in response to the detected at least one gas flow characteristic.

12. The system of claim 1, further comprising a gas flow sensor disposed in the ventilator circuit, the gas flow sensor configured to detect a gas flow direction through the ventilator circuit and communicate the gas flow direction to the control device, wherein the control device is configured to direct the actuator to actuate and deliver medication from the canister to the ventilator circuit in response to the gas flow sensor detecting a gas flow direction from the ventilator to the patient.

13. The system of claim 1, wherein the control device is configured to:

(i) lock the unit to prevent actuation of the actuator and prevent unwanted adjustment of operational parameters;

(ii) receive identification information associated with an operator of the unit;

(iii) verify that the operator is an authorized user based on the identification information; and

(iv) unlock the unit and direct the actuator to actuate and deliver medication from the canister to the ventilator circuit in response to verification that the operator is an authorized user.

14. The system of claim 1, wherein the control device is configured to:

(i) lock the unit to prevent actuation of the actuator and prevent unwanted adjustment of operational parameters;

(ii) receive identification information associated with a patient;

(iii) verify that the patient is to receive the medication contained in the canister based on the identification information; and

(iv) unlock the unit and direct the actuator to actuate and deliver medication from the canister to the ventilator circuit in response to verification that the patient is to receive the medication contained in the canister.

15. The system of claim 1, wherein the control device is configured to:

(i) lock the unit to prevent actuation of the actuator and prevent unwanted adjustment of operational parameters;

(ii) receive identification information associated with the patient;

(iii) electronically identify the canister that is held by the housing;

(iv) verify that the patient is to receive the medication contained in the canister based on the identification information associated with the patient and the electronic identification of the canister; and

(v) unlock the unit and direct the actuator to actuate and deliver medication from the canister to the ventilator circuit in response to verification that the patient is to receive the medication contained in the inhaler.

16. The system of claim 1, wherein the delivery unit is releasably attached to the connector by at least one holding member that holds the housing in place.

17. The system of claim 1, wherein the delivery unit comprises an identification device configured to electronically identify the canister held by the housing.