Cardiac resynchronization therapy loss diagnostics

• US 9,216,295 B2
• Filed: 11/15/2011
• Issued: 12/22/2015
• Est. Priority Date: 10/31/2011
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Landman, Sean R., Stadler, Robert W.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Morales, Jon Eric C
• Application Number:
  US13/297,104
• Publication Number:
  US 20130110191A1
• Time in Patent Office: 1,498 Days
• Field of Search: 600/513
• US Class Current: 1/1
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/3682 with a variable atrioventricular delay
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer
• CPC Class Codes: A61N 1/37282 characterised by communication with experts in remote locations using a network

Abstract

In some examples, an IMD provides CRT data that indicates an amount of time that CRT was not delivered by the IMD, such as the % CRT. In some examples, a CRT loss diagnosis module apportions the amount of time that CRT was not delivered amongst predetermined reasons for loss of CRT based on the CRT data and sensed cardiac data from the IMD. An external computing device may present a representation of the apportionment to a user, e.g., a clinician. The external computing device may also analyze the apportionment, and recommend programming changes for the delivery of CRT by the IMD based on the analysis.

Claims

1. A system comprising:

a processor configured to receive data generated by an implantable medical device (IMD) that is configured to deliver cardiac resynchronization therapy (CRT), wherein the received data comprises CRT data and sensed cardiac data, wherein the CRT data indicates an amount of time for which the IMD did not deliver CRT to a patient, and wherein the sensed cardiac data indicates intrinsic cardiac activity of the patient that was sensed by the IMD; and

a CRT loss diagnosis module configured to analyze the CRT data and the sensed cardiac data, and apportion the amount of time amongst a plurality of predetermined reasons for CRT loss based on the analysis.

2. The system of claim 1,

wherein the amount of time comprises a percentage of a period of time, and

wherein the CRT loss diagnosis module is configured to determine a percentage for each of the predetermined reasons.

3. The system of claim 1, wherein the plurality of predetermined reasons for CRT loss comprises at least one of atrial tachyarrhythmia or premature ventricular contractions.

4. The system of claim 3,

wherein the sensed cardiac data received from the IMD indicates an amount of atrial tachyarrhythmia experienced by the patient, and

wherein the CRT loss diagnosis module apportions a portion of the amount of time for which the IMD did not deliver CRT to the patient to the predetermined reason of atrial tachyarrhythmia based on the amount of atrial tachyarrhythmia.

5. The system of claim 3,

wherein the sensed cardiac data received from the IMD indicates an amount of premature ventricular contractions experienced by the patient, and

wherein the CRT loss diagnosis module apportions a portion of the amount of time for which the IMD did not deliver CRT to the patient to the predetermined reason of premature ventricular contractions based on the amount of premature ventricular contractions.

6. The system of claim 3,

wherein the sensed cardiac data comprises data for one or more ventricular sense episodes, the data for each of the ventricular sense episodes including data indicating the occurrence and timing of atrial and ventricular events during the ventricular sense episode,

wherein ventricular sense episodes are tachyarrhythmia episodes detected by an IMD based on intervals between adjacent ventricular events during the episode meeting a tachyarrhythmia criterion, and

wherein the plurality of predetermined reasons for CRT loss comprises ventricular sense episodes.

7. The system of claim 6,

wherein the sensed cardiac data received from the IMD indicates an amount of ventricular sense episodes experienced by the patient, and

wherein the CRT loss diagnosis module apportions a portion of the amount of time for which the IMD did not deliver CRT to the patient to the predetermined reason of ventricular sense episodes based on the amount of ventricular sense episodes.

8. The system of claim 6,

further comprising an episode classification module configured to analyze the sensed cardiac data for the ventricular sense episodes, and classify each of ventricular sense episodes as one of a plurality of predetermined classifications based on the analysis,

wherein the plurality of predetermined reasons for CRT loss comprises at least some of the predetermined classifications, and

wherein the CRT loss diagnosis module is configured to apportion at least some the amount of time to the predetermined classifications as reasons for CRT loss based on the classifications of the ventricular sense episodes by the episode classification module.

9. The system of claim 8, wherein the predetermined classifications comprise at least one of a ventricular tachyarrhythmia classification, a supraventricular classification, or a ventricular oversensing classification.

10. The system of claim 8, wherein the predetermined classifications comprise at least one of a programmed atrioventricular interval length classification, a programmed pacing mode classification, an atrial undersensing classification, an atrial refractory sense to ventricular sense classification, or a junctional rhythm classification.

11. The system of claim 1, further comprising an external computing device configured to present a representation of the apportionment of the amount of time amongst the plurality of predetermined reasons to a user.

12. The system of claim 11, wherein the external computing device is configured to:

analyze the apportionment of the amount of time amongst the plurality of predetermined reasons; and

recommend modification of at least one programmable parameter of the IMD to the user based on the apportionment.