System for forming an array of emulsions
DCFirst Claim
1. A system for forming an array of emulsions, comprising:
- a plate including an array of emulsion production units, each unit includingat least one first input well to hold a continuous phase for an emulsion,a second input well to hold a dispersed phase for an emulsion, andan output well connected to the first and second input wells by a set of channels that form a channel junction, the set of channels including at least two input channels extending separately from the input wells to the channel junction and an output channel extending from the channel junction to the output well, each channel of the set of channels being circumferentially bounded; and
a vacuum or pressure source configured to be connected operatively to wells of the plate to form a pressure drop between the input wells and the output well of each unit to drive the continuous phase and the dispersed phase from the first and second input wells of the unit to the channel junction, at which droplets of the dispersed phase are generated, and through the output channel for collection in the output well of the unit.
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Accused Products
Abstract
System, including apparatus and methods, for forming an array of emulsions. The system may comprise a plate including an array of emulsion production units. Each unit may include at least one first input well, a second input well, and an output well connected to the first and second input wells by channels that form a droplet generator. The system also may comprise a vacuum or pressure source configured to be connected operatively to wells of the plate to form a pressure drop between the input wells and the output well of each unit that is capable of driving a first fluid and a second fluid from respective first and second input wells of such unit and through the droplet generator, for collection as an emulsion in the output well of such unit.
369 Citations
21 Claims
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1. A system for forming an array of emulsions, comprising:
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a plate including an array of emulsion production units, each unit including at least one first input well to hold a continuous phase for an emulsion, a second input well to hold a dispersed phase for an emulsion, and an output well connected to the first and second input wells by a set of channels that form a channel junction, the set of channels including at least two input channels extending separately from the input wells to the channel junction and an output channel extending from the channel junction to the output well, each channel of the set of channels being circumferentially bounded; and a vacuum or pressure source configured to be connected operatively to wells of the plate to form a pressure drop between the input wells and the output well of each unit to drive the continuous phase and the dispersed phase from the first and second input wells of the unit to the channel junction, at which droplets of the dispersed phase are generated, and through the output channel for collection in the output well of the unit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification