System and method for reconstructing cardiac activation information
First Claim
1. A method of reconstructing cardiac activation information, the method comprising:
- processing, by a computing device, an analysis cardiac signal and a reference cardiac signal to determine a first point of change in a derivative of the analysis cardiac signal with respect to a derivative of the reference cardiac signal, the derivative of the analysis cardiac signal and the derivative of the reference cardiac signal being selected from zero, first and second order derivative;
processing, by the computing device, the analysis cardiac signal and the reference cardiac signal to determine a second point of change in a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal, the different derivative of the analysis cardiac signal and the different derivative of the reference cardiac signal being selected from zero, first and second order derivative; and
assigning an activation onset time in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal.
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Abstract
In a system and method for reconstructing cardiac activation information, an analysis cardiac signal and a reference cardiac signal are processed to determine a first point of change in a derivative of the analysis cardiac signal with respect to a derivative of the reference cardiac signal. The analysis cardiac signal and the reference cardiac signal are processed to determine a second point of change in a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal. An activation onset time is assigned in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal.
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Citations
37 Claims
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1. A method of reconstructing cardiac activation information, the method comprising:
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processing, by a computing device, an analysis cardiac signal and a reference cardiac signal to determine a first point of change in a derivative of the analysis cardiac signal with respect to a derivative of the reference cardiac signal, the derivative of the analysis cardiac signal and the derivative of the reference cardiac signal being selected from zero, first and second order derivative; processing, by the computing device, the analysis cardiac signal and the reference cardiac signal to determine a second point of change in a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal, the different derivative of the analysis cardiac signal and the different derivative of the reference cardiac signal being selected from zero, first and second order derivative; and assigning an activation onset time in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A system to reconstruct cardiac activation information comprising:
at least one computing device configured to; process an analysis cardiac signal and a reference cardiac signal to determine a first point of change in a derivative of the analysis cardiac signal with respect to a derivative of the reference cardiac signal, the derivative of the analysis cardiac signal and the derivative of the reference cardiac signal being selected from zero, first and second order derivative; process the analysis cardiac signal and the reference cardiac signal to determine a second point of change in a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal, the different derivative of the analysis cardiac signal and the different derivative of the reference cardiac signal being selected from zero, first and second order derivative; and assign an activation onset time in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A method of treating a cardiac rhythm disorder, the method comprising:
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iteratively accessing an analysis cardiac signal and a reference cardiac signal from a plurality of cardiac signals; processing, by a computing device, the analysis cardiac signal and the reference cardiac signal to determine a first point of change in a derivative of the analysis cardiac signal with respect to a derivative of the reference cardiac signal, the derivative of the analysis cardiac signal and the derivative of the reference cardiac signal being selected from zero, first and second order derivative; processing, by the computing device, the analysis cardiac signal and the reference cardiac signal to determine a second point of change in a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal above a second threshold, the different derivative of the analysis cardiac signal and the different derivative of the reference cardiac signal being selected from zero, first and second order derivative; assigning activation onset times in the analysis cardiac signal at points based on a mathematical association of first points of change and second points of change to define cardiac activations indicating beats in the analysis cardiac signal; reconstructing a cardiac activation pattern based on the assigned activation onset times to indicate a source of the cardiac rhythm disorder; and treating cardiac tissue at the source to suppress or eliminate the cardiac rhythm disorder.
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Specification