Embolus removal systems with baskets

• US 9,220,522 B2
• Filed: 07/30/2008
• Issued: 12/29/2015
• Est. Priority Date: 10/17/2007
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Fulkerson, John, Ferrera, David A.
• Primary Examiner(s): NGUYEN, TUAN VAN
• Application Number:
  US12/182,370
• Publication Number:
  US 20090105722A1
• Time in Patent Office: 2,708 Days
• Field of Search: 606/200, 606/113, 606/114, 606/159, 606/198, 606/127
• US Class Current: 1/1
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22039 eccentric
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils

Abstract

Systems for treatment of ischemic stroke can include tethered baskets. A basket can be tethered to a pusher or elongate member. A temporary reperfusion device or temporary capture device also can be tethered to the pusher or elongate member.

Claims

1. A system for the removal of emboli within neurovasculature comprising:

a temporary reperfusion device;

wherein said reperfusion device comprises a pusher and a self-expanding distal nitinol device eccentrically tethered to the pusher with a plurality of tethers to facilitate withdrawal of said reperfusion device;

wherein said self-expanding distal nitinol device is configured for placement and expansion within an embolus to facilitate blood flow by compressing the embolus, said blood flow causing lysis of at least a portion of the embolus;

wherein said self-expanding distal nitinol device comprises a generally cylindrical body having an open proximal end and an open distal end;

wherein, when said generally cylindrical body is in an expanded state, the generally cylindrical body further facilitates blood flow by providing continuous radial pressure at the location of the embolus to enhance natural lysis of the embolus;

a mesh basket tethered to the pusher and having at least an undeployed state and a deployed state, the mesh basket being configured to be inserted into neurovasculature in the undeployed state and removed from the neurovasculature in its deployed state;

wherein the mesh basket is configured for retrieving all or part of any remaining portion of the embolus post reperfusion;

wherein the mesh basket has a closed distal end;

wherein the mesh basket is configured to be deployed into its deployed state distal to at least a section of any remaining embolus portion and expanded to capture the remaining embolus portion;

wherein the mesh basket is suitable for deployment above the subclavian artery and common carotid artery; and

wherein the mesh basket has radiopacity at a distal end of the mesh basket.

2. The system of claim 1, said radiopacity further comprised of at least a peg, selected from the group consisting of platinum and gold, the peg being pressed into pre-laser cut apertures at a distal end of the mesh basket.

3. The system of claim 1, wherein a polymeric liner is incorporated within the pusher to improve guidewire trackability.

4. The system of claim 3, wherein the polymeric liner is extended beyond the distal tip of the pusher.

5. The system of claim 4 whereby guidewire entanglement in the nitinol device is prevented, by the extended polymeric liner.

6. The system of claim 5, wherein the mesh basket further comprises uniform cells.

7. The system of claim 1, wherein the mesh basket is eccentrically tethered to the pusher.

8. A system for removing an embolus within neurovasculature, comprising:

a microcatheter configured to be inserted to a position such that a distal end of the microcatheter is distal to the embolus;

a temporary capture device configured to be inserted through the microcatheter to a location distal to a portion of the embolus, said capture device comprising an elongate member and a self-expanding distal device eccentrically tethered to the elongate member with a plurality of tethers to facilitate withdrawal of said capture device; and

a mesh basket having an open proximal end and a closed distal end and being tethered to the elongate member for deployment distal to said capture device;

wherein said self-expanding distal device is configured for placement and expansion within the embolus to facilitate increased blood flow by compressing the embolus, thereby enhancing natural lysis of the embolus due to the increased blood flow;

wherein said self-expanding distal device comprises a generally cylindrical body having an open distal end;

wherein the capture device is configured to be deployed and removed;

wherein the self-expanding device is configured to capture at least a portion of the embolus on an external surface of the generally cylindrical body.

9. The system of claim 8, wherein said generally cylindrical body comprises an open-cell structure configured to grab at least a portion of the embolus.

10. The system of claim 8, wherein said generally cylindrical body comprises a woven pattern.

11. The system of claim 8, wherein the mesh basket is configured for offset deployment.

12. A system for removing an embolus within neurovasculature, comprising:

a microcatheter configured to be inserted to a location such that a distal end of the microcatheter is distal to the embolus;

a temporary reperfusion device configured to be delivered through the microcatheter, said reperfusion device comprising an elongate member and a self-expanding distal device eccentrically tethered to the elongate member with a plurality of tethers to facilitate withdrawal of said reperfusion device; and

an embolus capture basket having an open proximal end and a closed distal end, the embolus capture basket being tethered to the elongate member for deployment distal to said reperfusion device;

wherein said reperfusion device is configured for placement and expansion within an embolus to facilitate blood flow by compressing the embolus;

wherein said self-expanding distal device comprises a generally cylindrical body having an open proximal end and an open distal end;

wherein, in use, the microcatheter is advanced to a location such that a distal end of the microcatheter is distal to the embolus and then the self-expanding distal device is deployed within the embolus to create a channel for blood flow, thereby providing vessel reperfusion due to natural lytic action; and

wherein said reperfusion device is configured to capture at least a portion of the embolus post reperfusion on an external surface of the generally cylindrical body.

13. The system of claim 12, wherein said generally cylindrical body comprises an open-cell structure configured to grab at least a portion of the embolus.

14. The system of claim 12, wherein said generally cylindrical body comprises a woven pattern.

15. The system of claim 12, wherein the embolus capture basket is configured for offset deployment such that the embolus capture basket occupies about the center of vessel when deployed along an offset guidewire.