Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury

• US 9,220,561 B2
• Filed: 01/19/2012
• Issued: 12/29/2015
• Est. Priority Date: 01/19/2011
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Jenson, Mark L., Crow, Loren M.
• Primary Examiner(s): LAURITZEN, AMANDA L
• Application Number:
  US13/353,948
• Publication Number:
  US 20120265066A1
• Time in Patent Office: 1,440 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00473 Distal part, e.g. tip or head A61B2017/00464 takes precedence
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00511 Kidney
• CPC Class Codes: A61B 2090/0808 for indicating correct assembly of components, e.g. of the surgical apparatus
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

A first catheter is dimensioned for deployment within a renal artery. A second catheter has a shaft with an outer diameter smaller than an inner diameter of the first catheter'"'"'s open lumen. A gap is formed between the shaft and the first catheter when the second catheter is situated within the first catheter. The gap facilitates transport of a fluid, such as imaging contrast media, along the first catheter. An electrode arrangement at the distal end of the shaft is configured to deliver ablative energy to perivascular renal nerves, and has an outer diameter about the same size as the inner diameter of the first catheter such that a fit therebetween substantially blocks fluid flow within the gap yet provides for relative movement between the electrode arrangement and the luminal wall. A conductor extends between the proximal and distal ends of the shaft and is coupled to electrode arrangement.

Claims

1. An intravascular apparatus, comprising:

a first catheter dimensioned for deployment within a renal artery of a patient and having an open lumen with an inner diameter, a proximal end, a distal end, and a length sufficient to access the renal artery relative to a percutaneous access location; and

a second catheter dimensioned for deployment within the first catheter and comprising;

a shaft having a proximal end, a distal end, and a length sufficient to access the renal artery relative to the percutaneous access location, the shaft having an outer diameter that is smaller than the inner diameter of the first catheter'"'"'s open lumen so as to form a gap between the shaft and a luminal wall of the first catheter when the second catheter is situated within the open lumen of the first catheter, the gap facilitating transport of a fluid along a length of the first catheter;

a non-expandable electrode arrangement provided at the distal end of the shaft and configured to deliver energy sufficient to ablate perivascular renal nerve tissue, the electrode arrangement having an outer diameter the same size as the inner diameter of the open lumen of the first catheter such that a fit between the electrode arrangement and the luminal wall of the first catheter blocks fluid flow within the gap yet provides for relative movement between the electrode arrangement and the luminal wall; and

a conductor extending between the proximal and distal ends of the shaft and coupled to electrode arrangement.

2. The apparatus of claim 1, wherein the first catheter is configured as a guide catheter.

3. The apparatus of claim 1, wherein the first catheter is a sheath.

4. The apparatus of claim 1, wherein an outer diameter of the first catheter is 6 French (Fr).

5. The apparatus of claim 1, wherein the outer diameter of the electrode arrangement is 5 Fr or larger.

6. The apparatus of claim 1, wherein the outer diameter of the electrode arrangement is 5 Fr.

7. The apparatus of claim 1, wherein the outer diameter of the electrode arrangement is 6 French.

8. The apparatus of claim 1, wherein the fluid comprises imaging contrast media.

9. A system comprising the apparatus of claim 1, wherein the system comprises:

a high-frequency AC generator coupled to the second catheter; and

a power control coupled to the generator and configured to control delivery of high-frequency AC energy to the electrode arrangement sufficient to ablate perivascular renal nerve tissue in an automatic or semi-automatic mode of operation.

10. An intravascular apparatus, comprising:

a first catheter dimensioned for deployment within a renal artery of a patient and having an open lumen with an inner diameter, a proximal end, a distal end, and a length sufficient to access the renal artery relative to a percutaneous access location; and

a second catheter dimensioned for deployment within the first catheter and comprising;

a shaft having a proximal end, a distal end, and a length sufficient to access the renal artery relative to the percutaneous access location, the shaft having an outer diameter that is smaller than the inner diameter of the first catheter'"'"'s open lumen so as to form a gap between the shaft and a luminal wall of the first catheter when the second catheter is situated within the open lumen of the first catheter, the gap facilitating transport of a fluid along a length of the first catheter;

a non-expandable electrode arrangement provided at the distal end of the shaft and configured to deliver energy sufficient to ablate perivascular renal nerve tissue, the electrode arrangement having an outer diameter the same size as or larger than the inner diameter of the open lumen of the first catheter such that a fit between the electrode arrangement and the first catheter blocks fluid flow within the gap; and

a conductor extending between the proximal and distal ends of the shaft and coupled to electrode arrangement.

11. The apparatus of claim 10, wherein the first catheter is configured as a guide catheter.

12. The apparatus of claim 10, wherein the first catheter is a sheath.

13. The apparatus of claim 10, wherein an outer diameter of the first catheter is 6 Fr.

14. The apparatus of claim 10, wherein the outer diameter of the electrode arrangement is 5 Fr or larger.

15. The apparatus of claim 10, wherein the outer diameter of the electrode arrangement is 5 Fr.

16. The apparatus of claim 10, wherein the outer diameter of the electrode arrangement is 6 French.

17. The apparatus of claim 10, wherein the fluid comprises imaging contrast media.