Mosaic implants, kits and methods for correcting bone defects

• US 9,220,597 B2
• Filed: 02/12/2014
• Issued: 12/29/2015
• Est. Priority Date: 02/12/2013
• Status: Active Grant

• Current Assignee: Ossdsign AB
• Original Assignee: Ossdsign AB
• Inventors: Engstrand, Thomas, Bohlin, Jan, berg, Jonas, Engqvist, Hkan
• Primary Examiner(s): Stewart, Alvin
• Application Number:
  US14/179,205
• Publication Number:
  US 20140228969A1
• Time in Patent Office: 685 Days
• Field of Search: 606283-285, 606/94, 623/1.21, 623/1.17, 623/17.19, 623/17.18, 623/17.17
• US Class Current: 1/1
• CPC Class Codes: A61B 17/688 for reattaching pieces of the skull
• CPC Class Codes: A61B 17/8085 with pliable or malleable elements or having a mesh-like structure, e.g. small strips A61B17/8071, A61B17/8076 take precedence
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/2846 Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects nets or sleeves applied to surface of endoprostheses A61F2/30907; bone plates A61B17/80; bone regeneration in dental surgery A61C8/0006
• CPC Class Codes: A61F 2/2875 Skull or cranium A61F2/2803 and A61F2/3099 take precedence
• CPC Class Codes: A61F 2/30965 Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
• CPC Class Codes: A61F 2002/30143 hexagonal
• CPC Class Codes: A61F 2002/30324 differing in thickness
• CPC Class Codes: A61F 2002/30451 soldered or brazed or welded
• CPC Class Codes: A61F 2002/30462 retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2002/30578 having apertures, e.g. for receiving fixation screws
• CPC Class Codes: A61F 2002/3092 having an open-celled or open-pored structure
• CPC Class Codes: A61F 2002/30957 using a positive or a negative model, e.g. moulds
• CPC Class Codes: A61F 2002/3096 trimmed or cut to a customised size
• CPC Class Codes: A61F 2002/30985 using three dimensional printing [3DP]
• CPC Class Codes: A61F 2310/00353 Bone cement, e.g. polymethylmethacrylate or PMMA

Abstract

A mosaic implant conformable to a curved surface, comprising first and second implant sections coupled along a beam portion extending across a length of the implant, each of the implant sections having

• • a plurality of biocompatible mosaic plates, and
  • a plurality of wires which interconnect the plates with one another.
    The mosaic implant is configured to be deformable such that at least a portion of the mosaic implant is conformable to a curved surface, with the beam portion providing structural support which resists inward deformation of the curved portion of the implant. A kit for forming a mosaic implant is also provided, along with a method for correcting a bone defect in a patient.

Claims

1. A mosaic implant conformable to a curved surface, comprising first and second implant sections coupled along a beam portion extending across a length of the implant, each of said first and second implant sections having

a plurality of biocompatible mosaic plates, wherein said biocompatible mosaic plates comprise a hydraulic cement composition, and

a plurality of wires which interconnect the plates with one another,

wherein the mosaic implant is configured to be deformable such that at least one portion of the mosaic implant is conformable to a curved surface, and further wherein said beam portion provides structural support which resists inward deformation of said at least one portion of the implant.

2. The mosaic implant of claim 1, wherein the mosaic implant is configured to be deformable both along the length of the beam portion and in a second direction which is transverse to the length of the beam portion.

3. The mosaic implant of claim 2 wherein said beam portion is integral with at least one of said first and second implant sections.

4. The mosaic implant of claim 3, wherein said beam portion comprises at least one wire rim which extends along a side of the implant section located adjacent the other implant section.

5. The mosaic implant of claim 1 further comprising a support girder extending across at least a portion of one of said implant sections.

6. The mosaic implant of claim 5, comprising a plurality of support girders spaced from each other.

7. The mosaic implant of claim 1, wherein at least a portion of the mosaic implant is deformable to a substantially spheroidal surface.

8. The mosaic implant of claim 1, wherein said first and second implant sections have different geometrical shapes.

9. The mosaic implant of claim 8, wherein at least one of the implant sections has a tapered width along at least a portion of its length.

10. The mosaic implant of claim 1, wherein said plurality of wires of said first and second implant sections comprise wire mesh.

11. The mosaic implant of claim 10 wherein said wire mesh includes deformation zones located between adjacent mosaic plates which facilitate deformation of the mosaic implant so as to conform at least a portion of the implant to a curved surface.

12. The mosaic implant of claim 10, wherein said wire mesh comprises a plurality of wire segments and a plurality of eyelets, wherein the wire segments are connected to each other by said eyelets.

13. The mosaic implant of claim 12, wherein a portion of said plurality of eyelets are located along the periphery of the implant and are adapted to receive a fastener for securing the implant within a patient, with the remainder of the eyelets enclosed within said plates.

14. The mosaic implant of claim 12, wherein each of said implant sections includes a support frame comprising said wire mesh and a wire rim which extends along at least one side of the implant section, and further wherein the implant sections are attached to one another along adjoining rims such that said beam section is provided by the attached rims of the implant sections.

15. The mosaic implant of claim 1, further comprising a third implant section coupled to the second implant section along a second beam portion extending across a length of the implant, said third implant section comprising a plurality of biocompatible mosaic plates and a plurality of wires which interconnect the plates with one another.

16. The mosaic implant of claim 1, wherein said implant sections include a plurality of fastening points which facilitate attachment of the mosaic implant in a patient.

17. The mosaic implant of claim 1, wherein said biocompatible mosaic plates comprise a cement comprising at least 55 wt. % monetite.

18. A kit for forming a mosaic implant, comprising a plurality of implant sections, each of said implant sections comprising

a plurality of biocompatible mosaic plates, wherein said biocompatible mosaic plates comprise a hydraulic cement composition, and

a plurality of wires which interconnect the plates with one another

wherein pairs of said implant sections are configured for attachment to one another along or to a beam portion extending across a length of the assembled implant, further wherein the assembled mosaic implant is deformable such that at least one portion of the mosaic implant is conformable to a curved surface, with said beam portion providing structural support which resists inward deformation of said at least one portion of the implant.

19. The kit of claim 18, wherein said plurality of wires of said implant sections comprise wire mesh, and further wherein said wire mesh includes deformation zones located between adjacent mosaic plates which facilitate deformation of the mosaic implant so as to conform at least a portion of the assembled implant to a curved surface.

20. The kit of claim 18, wherein each of said implant sections includes at least one wire rim which extends along a side of the implant section, said implant sections attachable to one another along their respective rims such that said beam section is provided by the attached rims of adjacent implant sections of the assembled implant.

21. A method for correcting a bone defect in a patient, comprising:

(a) providing a mosaic implant comprising first and second implant sections coupled along a beam portion extending across a length of the implant, each of said first and second implant sections having

a plurality of biocompatible mosaic plates, wherein said biocompatible mosaic plates comprise a hydraulic cement composition, and

a plurality of wires which interconnect the plates with one another;

(b) deforming the mosaic implant to a shape corresponding to a desired shape for the patient'"'"'s bone defect such that at least one portion of the mosaic implant conforms to a curved surface;

(c) positioning the implant at the site of the bone defect in the patient; and

(d) securing the implant in place;

wherein the beam portion of the implant provides structural support which resists inward deformation of said at least one portion of the implant.