Dialysis systems and methods

• US 9,220,832 B2
• Filed: 01/07/2011
• Issued: 12/29/2015
• Est. Priority Date: 01/07/2010
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Inventors: Weaver, Colin, Crnkovich, Martin Joseph
• Primary Examiner(s): BASS, DIRK R
• Application Number:
  US13/520,082
• Publication Number:
  US 20130018301A1
• Time in Patent Office: 1,817 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61M 1/152 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/36224 with sensing means or components thereof
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 1/3641 Pressure isolators
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 2205/707 Testing of filters for clogging
• CPC Class Codes: A61M 2205/7536 allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes

Abstract

This invention relates to dialysis systems and methods. In some implementations, a method includes applying vacuum pressure to a device of a dialysis system, and then determining, based on a detected fluid level or measured pressure, whether the device is functioning properly.

Claims

1. A method, comprising:

applying vacuum pressure to a chamber of an air release device of a dialysis system, the air release device comprising a vent;

after applying the vacuum pressure to the air release device, measuring a pressure within a fluid line that is fluidly connected to the air release device; and

determining, based on the measured pressure, whether air is being drawn into the chamber of the air release device through the vent.

2. The method of claim 1, wherein the measured pressure is transmitted in the form of a signal to a control unit of the dialysis system.

3. The method of claim 2, wherein the control unit is a microprocessor.

4. The method of claim 1, wherein the pressure is measured by a pressure sensor of the dialysis system.

5. The method of claim 4, wherein the pressure sensor comprises a pressure transducer.

6. The method of claim 4, wherein the pressure sensor is attached to a dialysis machine of the dialysis system and is aligned with the fluid line.

7. The method of claim 1, wherein the vacuum pressure is applied to the chamber of the air release device by activating a pump.

8. The method of claim 7, wherein the line is in fluid communication with a dialyzer, a dialysate line is in fluid communication with the dialyzer, and the pump is an ultrafiltrate pump that is fluidly connected to the dialysate line.

9. The method of claim 7, wherein the pump is a drug pump that is configured to introduce fluid into the fluid line when operated in a first direction and is configured to draw fluid out of the fluid line when operated in a second direction.

10. The method of claim 9, wherein applying the vacuum pressure comprises operating the drug pump in the second direction.

11. The method of claim 1, wherein applying vacuum pressure to the chamber of the air release device comprises closing off lines upstream and downstream of the air release device and activating a first pump in fluid communication with a portion of the lines between locations where the lines are closed off.

12. The method of claim 11, wherein closing off the line upstream of the air release device comprises turning off a second pump configured to circulate fluid through the lines, and closing off the line downstream of the air release device comprises clamping the line downstream of the air release device.

13. The method of claim 12, wherein the first pump is an ultrafiltration pump.

14. The method of claim 12, further comprising misbalancing a balancing chamber that is in fluid communication with the chamber of the air release device to apply vacuum pressure to the chamber of the air release device.

15. The method of claim 1, wherein the dialysis system comprises first and second lines connected to the air release device and a pump configured to circulate fluid from the first line to the air release device to the second line during dialysis treatment, and wherein applying vacuum pressure to the chamber of the air release device comprises closing off the second line and operating the pump in a manner to circulate fluid from the second line to the air release device to the first line.

16. The method of claim 1, wherein determining, based on the measured pressure, whether air is being drawn into the chamber comprises determining if the measured pressure is less than a desired pressure.

17. The method of claim 16, further comprising indicating to a user that the air release device is not functioning properly if the measured pressure is less than the desired pressure.

18. The method of claim 17, wherein indicating to the user that the air release device is not functioning properly comprises emitting a visual signal.

19. The method of claim 17, wherein indicating to the user that the air release device is not functioning properly comprises emitting an audio signal.

20. The method of claim 17, wherein indicating to the user that the air release device is not functioning properly comprises disabling one or more functions of the dialysis system.

21. The method of claim 1, further comprising applying positive pressure to the chamber of the air release device after applying the vacuum pressure such that air drawn into the chamber of the air release device by the vacuum pressure is forced out of the chamber by the positive pressure.

22. The method of claim 1, wherein the device comprises a pressure transducer protector.

23. The method of claim 1, wherein the dialysis system is a hemodialysis system.

24. The method of claim 23, wherein the method is performed during hemodialysis treatment.

25. The method of claim 23, wherein the method is performed before hemodialysis treatment.

26. The method of claim 1, wherein the fluid line contains saline.

27. The method of claim 1, wherein the fluid line contains blood.

29. The method of claim 1, wherein the vacuum pressure is applied to the chamber of the air release device of the dialysis system during priming of the dialysis system.

28. A method, comprising:

applying vacuum pressure to a chamber of an air release device of a dialysis system, the device comprising a vent;

after applying the vacuum pressure to the chamber of the air release device, measuring a pressure within a fluid line that is fluidly connected to the device; and

if the measured pressure is less than a certain pressure, indicating to a user that air is being drawn into the chamber of the air release device through the vent.