Medicament infusion systems

• US 9,220,833 B2
• Filed: 06/14/2012
• Issued: 12/29/2015
• Est. Priority Date: 06/27/2011
• Status: Active Grant

• Current Assignee: Smiths Medical ASD, Inc. (Smiths Group International Holdings Ltd.)
• Original Assignee: Smiths Medical ASD, Inc. (Smiths Group International Holdings Ltd.)
• Inventors: Robert, Renee, Amborn, Chad, Clark, Geoff
• Primary Examiner(s): FLICK, JASON E
• Application Number:
  US13/517,782
• Publication Number:
  US 20120330238A1
• Time in Patent Office: 1,293 Days
• Field of Search: 604/151
• US Class Current: 1/1
• CPC Class Codes: A61M 2039/1094 at least partly incompatible with standard connectors, e.g. to prevent fatal mistakes in connection
• CPC Class Codes: A61M 39/1011 Locking means for securing connection; Additional tamper safeties A61M39/16 takes precedence
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16
• CPC Class Codes: A61M 5/14 Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
• CPC Class Codes: A61M 5/168 Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body flow control in general G05D7/00

Abstract

A drug delivery system has a fluid store that has a first tubing having an outlet fitted with a connector of a given configuration that prevents the connector from being coupled to a conventional counterpart connector. The system further has a tube retaining device that has a catheter extending out of one of its ends and an inlet connector at its other end that has a configuration complementary to the configuration of the outlet connector of the first tubing, so that the first tubing may be matingly connected to the tube retaining device to establish a through fluid path from the first tubing to the catheter. A one-way valve may be provided to the tubing to prevent fluid from flowing backwards into the tubing. The tubing can be selectively occluded and opened to regulate the flow of fluid from the tubing to the catheter.

Claims

1. A drug delivery system, comprising:

a fluid store for storing a medicament;

a first tubing having an inlet in fluid communication with said fluid store so that the medicament flows from said fluid store through said first tubing, said first tubing having an outlet first connector of a given configuration that prevents said outlet first connector from mating with a counterpart connector having a conventional luer configuration;

a tube retainer device having an inlet second connector and an outlet whereinto a proximal end of a second tubing for interfacing with a patient is inserted, the second tubing having a distal end to be inserted to the patient and the inlet second connector having a configuration complementary to said given configuration of said outlet first connector so that said inlet second connector is connectable only to said outlet first connector and not to a counterpart connector having a conventional luer configuration, the tube retainer device having an open position wherein the second tubing is removable from the tube retainer device and a closed position wherein the second tubing is fixedly held by the tube retainer device to establish a fluid communication path with the inlet second connector; and

a one way flow valve integrated to said outlet first connector to prevent back flow of the medicament from said second tubing to said first tubing to ensure that the medicament flows unidirectionally from said first tubing to said second tubing;

wherein a fluid through path is established for the medicament to flow from said fluid store to said second tubing through said first tubing when said outlet first connector and said inlet second connector of complementary given configurations are connected to each other.

2. A drug delivery system of claim 1, wherein said outlet first connector comprises a male connector having said given configuration and said inlet second connector comprises a female connector having a configuration complementary to said given configuration.

3. A delivery system of claim 1, wherein the inlet of said first tubing comprises a hollow spike that is inserted to said fluid store to establish a fluid path between said fluid store and said first tubing.

4. A drug delivery system of claim 1, further comprising a mount whereonto a portion of said first tubing is positioned, said mount being coupled to a computerized controlled pump having a flow control mechanism that interacts with the portion of said first tubing positioned onto the mount to selectively occlude and open said first tubing to control the flow of the medicament through said first tubing to thereby regulate the amount of medicament to be dispensed to the patient.

5. A drug delivery system of claim 1, wherein said tube retainer device comprises a clam shaped structure having two clam members that are pivotally closeable upon each other, and wherein said inlet second connector extends from one of said clam members;

and

wherein said second tubing comprises a catheter having the proximal end that connects to and extends from an inlet of said clam shaped structure to establish the fluid communication with the inlet second connector and the distal end to be inserted to the patient, a proximal portion of the catheter being positioned between said clam members so as to be fixedly grasped by said clam members when said clam members close upon each other, the catheter establishing a through path for the medicament to flow from said fluid store to the patient.

6. A drug delivery system of claim 1, further comprising a filter bondedly integrated to said first tubing to at least trap unwanted particulates from the medicament flowing through said first tubing.

7. A drug delivery system comprising:

a fluid store for storing a medicament;

a first tubing having an inlet in fluid communication connection with said fluid store so that the medicament flows from said fluid store through said first tubing, said first tubing having an outlet first connector of a given configuration that prevents said outlet first connector from connecting with a counterpart connector of a conventional luer configuration;

a tube retainer device having an inlet second connector and an outlet whereinto a first end of a second tubing for interfacing with a patient is inserted, the inlet second connector having the same said given configuration as said outlet first connector of said first tubing so that said inlet second connector is not connectable with a counterpart connector of a conventional luer configuration, the second tubing including another end to be inserted to the patient, the tube retainer device having an open position wherein the second tubing is removable from the tube retainer device and a closed position wherein the second tubing is fixedly held by the tube retainer device to establish a fluid communication path with the inlet second connector; and

an extension tubing having a first end fitted with a third connector and a second end fitted with a fourth connector, said third and fourth connecters each having a configuration complementary to said given configuration so that said third connector is connectable with said first connector but not with a counterpart connector of a conventional luer configuration and said fourth connector is connectable with said second connector but not with a counterpart connector of a conventional luer configuration, said extension tubing connected to said first tubing via the coupling of said first and third connectors and to said tube retainer device via the coupling of said second and fourth connectors to establish a fluid through path from said fluid store to said second tubing.

8. A drug delivery system of claim 7, further comprising a one way valve integrated to said first connector to prevent back flow of the medicament from said extension tubing to said first tubing.

9. A drug delivery system of claim 7, further comprising a one way valve integrated to said fourth connector to prevent back flow of the medicament from said second tubing to said extension tubing.

10. A drug delivery system of claim 7, wherein said fluid store comprises a cassette having a mount whereonto a portion of said first tubing is positioned, said mount being coupled to a computerized controlled pump having a flow control mechanism that interacts with the portion of said first tubing positioned on the mount to selectively occlude and open said first tubing to control the flow of the medicament through said first tubing to thereby regulate the amount of medicament to flow to said second tubing.

11. A drug delivery system of claim 7, wherein said first connector of said first tubing may be disconnected from said third connector of said extension tubing and be connected to a syringe with a conventional connector having a configuration complementary to said given configuration.

12. A drug delivery system of claim 7, wherein said tube retainer device comprises a clam shaped structure having two clam members that are pivotally closeable upon each other, and wherein said second connector extends from one of said clam members;

and

wherein said second tubing comprises a catheter having the proximal end that connects to and extends from an inlet of said clam shaped structure to establish the fluid communication with the inlet second connector and the another end to be inserted to the patient, a proximal portion of the catheter being positioned between said clam members so as to be fixedly grasped by said clam members when said clam members close upon each other, the catheter establishing a through path for the medicament to flow from said fluid store to the patient.

13. A drug delivery system of claim 7, wherein said first connector and said second connector each comprise a female connector having said given configuration, and said third and fourth connectors each comprise a male connector having a configuration complementary to said given configuration.

14. A drug delivery system of claim 7, wherein said tube retainer device has a catheter for insertion to the patient, said tube retainer device including an inlet female connector having said given configuration, said system further comprising:

a filter having an inlet female connector of said given configuration for mating with said fourth connector and an outlet male connector having a configuration complementary to said given configuration;

wherein said female connector at the inlet of said tube retainer device and said outlet male connector of said filter are complementary coupled to each other to establish a fluid path between said extension tubing and the catheter of said tube retainer device via said filter.

15. A drug delivery system, comprising:

a fluid store for storing a medicament;

a first tubing having an inlet in fluid communication connection with said fluid store so that the medicament flows from said fluid store through said first tubing, said first tubing having an outlet female connector of a given configuration that prevents it from mating to a counterpart male connector of a conventional luer configuration;

a tube retainer device having a catheter for insertion to a patient including an inlet female connector having the same said given configuration as the outlet female connector of said first tubing, the inlet female connector of said tube retainer device not matable to a male connector of the conventional luer configuration, the tube retainer device having an open position wherein the catheter is movable from the tube retainer device and a closed position wherein the catheter is fixedly held by the tube retainer device to establish a fluid communication path with the inlet female connector;

an extension tubing having a first end male connector and a second end male connector each having a configuration complementary to said given configuration so that said first end male connector is matable to the outlet female connector of said first tubing but not to a female connector of a conventional luer configuration and said second end male connector is matable to the inlet female connector of said tube retainer device but not to a female connector of a conventional luer configuration;

wherein a fluid through path from said fluid store to said catheter is established when said extension tubing is coupled to said second tubing via the mating of its first end male connector with the outlet female connector of said first tubing and the mating of its second end male connector with the inlet female connector of said tube retainer device.

16. A drug delivery system of claim 15, further comprising:

a one way valve integrated to the second end male connector of said extension tubing that mates with the inlet female connector of said tube retainer device to prevent back flow of the medicament from said catheter to said extension tubing.

17. A drug delivery system of claim 15, wherein said fluid store comprises a cassette having a mount whereonto a portion of said first tubing is positioned, said mount being coupled to a computerized controlled pump having a flow control mechanism that interacts with the portion of said first tubing to selectively occlude and open said first tubing to control the flow of the medicament through said first tubing to thereby regulate the amount of medicament to flow to said catheter.

18. A drug delivery system of claim 15, wherein said tube retainer device comprises a clam shaped structure having two clam members that are pivotally closeable upon each other from the open position, and wherein said second end male connector extends from one of said clam members;

and

wherein said catheter has a proximal end that connects to and extends from an inlet of said clam shaped structure and a distal end to be inserted to the patient, a proximal portion of the catheter being positioned between said clam members so as to be fixedly grasped by said clam members when said clam members close upon each other in the closed position, the catheter establishing a through path for the medicament to flow from said fluid store to the patient.

19. A drug delivery system, comprising:

a fluid store for storing a medicament;

a first tubing having an inlet in fluid communication with said fluid store so that the medicament flows from said fluid store through said first tubing, said first tubing having an outlet male connector of a given configuration that prevents it from mating with a female connector of a conventional luer configuration;

a tube retainer device having a second tubing coupled thereto for insertion to a patient including an inlet female connector having a complementary configuration to said given configuration of said outlet male connector of said first tubing so that said inlet female connector is connectable only to said outlet male connector of said given configuration and not to a male connector of a conventional luer configuration to establish a through path for the medicament to flow from said fluid store to the patient through said first and second tubings when said outlet male connector and inlet female connector of complementary given configurations are connected to each other, the tube retainer device having an open position wherein the second tubing is removable from the tube retainer device and a closed position wherein the second tubing is fixedly held by the tube retainer device to establish a fluid communication path with the inlet female connector; and

a mount whereonto a portion of said first tubing is positioned, said mount being coupled to a computerized controlled pump having a flow control mechanism that interacts with the portion of said first tubing positioned on said mount to selectively occlude and open said first tubing to control the flow of the medicament through said first tubing to thereby regulate the amount of medicament dispensed to the patient.

20. A drug delivery system of claim 19, further comprising a one way flow valve integrated to said outlet male connector to prevent back flow of the medicament from said second tubing to said first tubing.