Systems for autofluorescent imaging and target ablation
First Claim
Patent Images
1. A method comprising:
- receiving a first input associated with a first dataset from a sensor of an intraluminal device to a computing device including a non-transitory signal-bearing medium, the first dataset including data representative of a target fluorescent response in one or more target cells to excitation energy of a first energy source of the intraluminal device;
receiving a second input associated with a second dataset from a targeting energy source of the intraluminal device to the computing device, the second dataset including data representative of a response to the targeting energy source including directional alignment of the first energy source with a second energy source of the intraluminal device, wherein the second energy source provides energy to at least partially ablate a target area by the second energy source; and
providing a first output in real time from the computing device to the second energy source, the first output providing data to activate the second energy source to provide energy to at least partially the target area by the second energy source based on a location of the target area calculated from the first dataset including data representative of the target fluorescent response, and the second dataset including data representative of the directional alignment from the targeting energy source.
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Abstract
Apparatus, devices, methods, systems, computer programs and computing devices related to autofluorescent imaging and ablation are disclosed.
353 Citations
49 Claims
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1. A method comprising:
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receiving a first input associated with a first dataset from a sensor of an intraluminal device to a computing device including a non-transitory signal-bearing medium, the first dataset including data representative of a target fluorescent response in one or more target cells to excitation energy of a first energy source of the intraluminal device; receiving a second input associated with a second dataset from a targeting energy source of the intraluminal device to the computing device, the second dataset including data representative of a response to the targeting energy source including directional alignment of the first energy source with a second energy source of the intraluminal device, wherein the second energy source provides energy to at least partially ablate a target area by the second energy source; and providing a first output in real time from the computing device to the second energy source, the first output providing data to activate the second energy source to provide energy to at least partially the target area by the second energy source based on a location of the target area calculated from the first dataset including data representative of the target fluorescent response, and the second dataset including data representative of the directional alignment from the targeting energy source. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A computer program product comprising:
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a signal bearing medium bearing at least one of one or more instructions for receiving a first input associated with a first dataset from a sensor of an intraluminal device to a non-transitory signal-bearing medium, the first dataset including data representative of a target fluorescent response in one or more target cells to a first energy source; at least one of one or more instructions for receiving a second input associated with a second dataset from a targeting energy source of the intraluminal device to the computing device, the second dataset including data representative of a response to the targeting energy source including directional alignment of the first energy source with a second energy source of the intraluminal device, wherein the second energy source provides energy to at least partially ablate a target area by the second energy source; and at least one of one or more instructions for providing a first output to the second energy source in real time, the first output providing data to activate the second energy source to provide energy to at least partially ablate the target area by the second energy source based on a location of the target area calculated from the first dataset including data representative of the target fluorescent response, and the second dataset including data representative of the directional alignment from the targeting energy source. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A system comprising:
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a computing device; and one or more instructions that when executed on the computing device cause the computing device to receive a first input associated with a first dataset from a sensor of an intraluminal device to a non-transitory signal-bearing medium, the first dataset including data representative of a target fluorescent response in one or more target cells to excitation energy of a first energy source of the intraluminal device; one or more instructions that when executed on the computing device cause the computing device to receive a second input associated with a second dataset from a targeting energy source of the intraluminal device to the computing device, the second dataset including data representative of a response to the targeting energy source including directional alignment of the first energy source with a second energy source of the intraluminal device, wherein the second energy source provides energy to at least partially ablate a target area by the second energy source; and one or more instructions that when executed on the computing device cause the computing device to provide a first output to activate a second energy source of the intraluminal device in real time, the first output providing data to the second energy source to provide energy to at least partially ablate the target area by the second energy source based on the first dataset including data representative of the target fluorescent response, and the second dataset including data representative of the directional alignment from the targeting energy source. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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38. A method comprising:
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receiving a first input associated with a first dataset from a sensor of an intraluminal device to a computing device including a non-transitory signal-bearing medium, the first dataset including data representative of a target fluorescent response in one or more target cells to excitation energy of a first energy source of the intraluminal device; receiving a second input associated with a second dataset from a targeting energy source of the intraluminal device to the computing device, the second dataset including data representative of a response to the targeting energy source including directional alignment of the first energy source with a second energy source of the intraluminal device, wherein the second energy source provides energy to at least partially ablate a target area by the second energy source; receiving a third input associated with a third dataset from a second sensor of the intraluminal device to the computing device, the third dataset including data representative of one or more environmental parameters; and providing a first output from the computing device to the second energy source in real time, the first output providing data to activate the second energy source to provide energy to at least partially ablate the target area by the second energy source based on a location of the target area calculated from the first dataset including data representative of the target fluorescent response, the second dataset including data representative of the directional alignment from the targeting energy source, and the third dataset including data representative of the one or more environmental parameters. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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Specification