MEMS check valve chip and methods

• US 9,226,851 B2
• Filed: 08/24/2013
• Issued: 01/05/2016
• Est. Priority Date: 08/24/2013
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Novartis Ag
• Inventors: Gunn, Nicholas Max
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US13/975,307
• Publication Number:
  US 20150057592A1
• Time in Patent Office: 864 Days
• Field of Search: 604/8, 604/9, 604/28, 606107-108, 623 1- 12, 424/422, 424/423
• US Class Current: 1/1
• CPC Class Codes: A61B 3/16 for measuring intraocular pressure, e.g. tonometers
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A MEMS check valve chip is described. The chip comprises a first side and an opposing second side, an outlet port extending from the first side to the second side, and a flexible outlet membrane anchored to the first side to overlie the outlet port. The flexible outlet membrane includes an outlet aperture and a sealing portion, and the sealing portion is movable between a closed position inhibiting fluid flow through the outlet aperture and an open position wherein the sealing portion displaces into the outlet port to permit fluid flow through the outlet aperture.

Claims

1. An IOP control device for implantation in an eye of a patient, comprising:

a first chip including;

a first side and an opposing second side; and

an outlet port extending from the first side to the second side and sized to permit fluid flow therethrough from the first side to the second side;

a second chip having an outer side and an inner side, wherein the first chip and the second chip stack to form a fluid flow passageway between the first side of the first chip and the inner side of the second chip, the fluid flow passageway having a fluid flow passageway pressure;

an inlet valve comprising a flexible inlet membrane, the flexible inlet membrane being movable between a closed position inhibiting fluid flow and an open position permitting fluid flow through the inlet valve; and

an outlet valve comprising a flexible outlet membrane anchored to the first side of the first chip to overlie the outlet port, the outlet membrane including at least one outlet aperture sized to permit fluid flow therethrough and a sealing portion, the sealing portion being movable between a closed position wherein the sealing portion deflects away from the second side toward fluid flow passageway to inhibit fluid flow through the outlet aperture and an open position wherein the sealing portion displaces into the outlet port toward the second side to permit fluid flow through the outlet aperture.

2. The IOP control device of claim 1, further comprising an outlet valve seat on the inner side of the second chip.

3. The IOP control device of claim 2, wherein the sealing portion of the outlet membrane is configured to deflect away from the second side of the first chip and selectively seal against the outlet valve seat and inhibit fluid flow through the outlet aperture when the outlet membrane is in a closed position.

4. The IOP control device of claim 2, wherein the flexible outlet membrane and the outlet valve seat are arranged to pre-bias the flexible outlet membrane over the outlet valve seat in a closed position when the outlet valve is in an unpressurized state.

5. The IOP control device of claim 2, wherein the outlet valve seat and the outlet aperture are aligned about a central axis extending through the valve seat.

6. The IOP control device of claim 2, wherein the outlet valve seat comprises a raised boss element.

7. The IOP control device of claim 6, wherein the raised boss element includes a diameter greater than a diameter of the outlet aperture.

8. The IOP control device of claim 1, further comprising an active component within the fluid flow passageway configured to affect fluid flow through the fluid flow passageway from the inlet port to the outlet port.

9. The IOP control device of claim 8, wherein the active component comprises an electrolytic actuator comprising a flow control chamber configured to contain a gas creating a flow control chamber pressure, an actuator fluid, an electrolysis system configured to affect the flow control chamber pressure by converting at least a portion of the actuator fluid to the gas, and a membrane configured to affect flow through the fluid flow passageway from the inlet port to the outlet port by deflecting in response to pressure differentials of the flow control chamber pressure and the fluid flow passageway pressure acting on opposing sides of the membrane.

10. The IOP control device of claim 1, wherein the flexible outlet membrane comprises an annular membrane with the outlet aperture positioned centrally in the membrane and the sealing portion encircles the outlet aperture.

11. The IOP control device of claim 1, further comprising an inlet port extending from the first side to the second side of the first chip and sized to permit fluid flow therethrough, wherein the flexible inlet membrane is disposed on the first side of the first chip.

12. The IOP control device of claim 1, further comprising an inlet port extending from the inner side to the outer side of the second chip and sized to permit fluid flow therethrough, wherein the flexible inlet membrane is disposed on the inner side of the second chip.