Systems and method of delivering fluids to a patient of varying concentration
First Claim
1. A method for injection of an imaging contrast into a patient, comprising:
- a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time, wherein the fluid injected in the first phase is generally iso-osmolar to blood plasma;
b. in a second phase, subsequent to the first phase, injecting a fluid having a second concentration of contrast agent for a second period of time, the second concentration being such that the osmolarity of the second phase is higher than the osmolarity of the first phase; and
c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time, the third concentration being such that the osmolarity of the third phase is lower than the osmolarity of the second phase,wherein the first concentration of contrast agent includes contrast,wherein the third concentration of contrast agent includes contrast, andwherein each of the first phase, the second phase, and the third phase proceed according to a set of injection parameters, including at least one of injection flow rate, injection volume, and injection duration, determined in advance of the first phase.
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Abstract
A method for injection of an imaging contrast into a patient, includes: a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time; and b. in a second phase, injecting a fluid having a second concentration of contrast agent for a second period of time. The osmolarity of the second phase is higher than the osmolarity of the first phase. The method can further include: c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time. The osmolarity of the third phase is lower than the osmolarity of the second phase. In embodiments in which the composition of the contrast agent of the third phase is the same as the composition of the contrast agent of the second phase, the third concentration can be lower than the second concentration.
9 Citations
38 Claims
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1. A method for injection of an imaging contrast into a patient, comprising:
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a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time, wherein the fluid injected in the first phase is generally iso-osmolar to blood plasma; b. in a second phase, subsequent to the first phase, injecting a fluid having a second concentration of contrast agent for a second period of time, the second concentration being such that the osmolarity of the second phase is higher than the osmolarity of the first phase; and c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time, the third concentration being such that the osmolarity of the third phase is lower than the osmolarity of the second phase, wherein the first concentration of contrast agent includes contrast, wherein the third concentration of contrast agent includes contrast, and wherein each of the first phase, the second phase, and the third phase proceed according to a set of injection parameters, including at least one of injection flow rate, injection volume, and injection duration, determined in advance of the first phase. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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Specification