Relating to a pen-type injector

• US 9,233,211 B2
• Filed: 03/02/2015
• Issued: 01/12/2016
• Est. Priority Date: 03/03/2003
• Status: Expired due to Term

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Veasey, Robert Frederick, Perkins, Robert, Plumptre, David Aubrey
• Primary Examiner(s): Mendez, Manuel
• Application Number:
  US14/635,573
• Publication Number:
  US 20150174334A1
• Time in Patent Office: 316 Days
• Field of Search: 604/187, 604207-211, 604/218, 604/221, 604/224, 604/232
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/2407 from the rear
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31528 by means of rotational movements, e.g. screw-thread mechanisms
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/31536 Blocking means to immobilize a selected dose, e.g. to administer equal doses
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/3156 using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
• CPC Class Codes: A61M 5/31563 interacting with a displaceable stop member
• CPC Class Codes: A61M 5/31565 Administration mechanisms, i.e. constructional features, modes of administering a dose dosing mechanisms for setting a dose A61M5/31533
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31578 based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 : Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
• CPC Class Codes: A61M 5/32 : Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Claims

1. A drive mechanism for use in a drug delivery device comprising:

a housing comprising an inner surface and an insert that is rotationally and axially fixed relative to the housing;

a drive sleeve having an outer surface, where a first end of the drive sleeve comprises a first radially extending flange and a second radially extending flange, where threads are disposed on the outer surface between the flanges and the first flange is configured to conform to a second side of the insert; and

a nut threadedly engaged with the threads on the outer surface of drive sleeve between the two radially extending flanges, where the nut has an outer surface keyed to the inner surface of the housing to prevent relative rotation between the nut and the housing while allowing relative longitudinal movement between the nut and the housing and where the nut translates distally relative to the drive sleeve during dose setting and is axially fixed relative to the drive sleeve during dose delivery.

2. The drive mechanism of claim 1 further characterized in that the nut has a radial stop on a second side that engages a corresponding stop on a first side of the second flange when the nut has reached a final dose dispensed position.

3. The drive mechanism of claim 1 where the nut has a stop on a first side that is configured to engage a radial stop on a second side of the first flange at a cartridge full position.

4. The drive mechanism of claim 3 where the threads on the outer surface of the drive sleeve between the two radially extending flanges is a part thread.

5. The drive mechanism of claim 4 further characterized in that the advance of the nut is proportional to a dialed dose.

6. The drive mechanism of claim 5 where the nut is a half nut configured to allow attachment to the outer surface of the drive sleeve between the two radially extending flanges.

7. The drive mechanism of claim 4 where the nut is configured to advance distally along the part thread when the drive sleeve is rotated during dose setting.

8. The drive mechanism of claim 6 where the nut is configured to advance proximally along the part thread when the drive sleeve is rotated to reduce an inadvertently set dose.