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Method and system for patient-specific modeling of blood flow

  • US 9,235,679 B2
  • Filed: 03/21/2014
  • Issued: 01/12/2016
  • Est. Priority Date: 08/12/2010
  • Status: Active Grant
First Claim
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1. A system for determining cardiovascular information for a patient, the system comprising:

  • at least one computer system configured to;

    receive patient-specific data regarding a geometry of an anatomical structure of the patient, the anatomical structure including at least a portion of one or more coronary arteries, and the patient-specific data including image data;

    create a three-dimensional model representing at least a portion of the anatomical structure of the patient using the patient-specific data;

    determine a myocardial mass of the patient using the patient-specific data;

    estimate total coronary blood flow of the patient using the determined myocardial mass;

    create a reduced-order blood flow model relating to a blood flow characteristic within the portion of the anatomical structure based, at least in part, on the estimated total coronary blood flow and the three-dimensional model;

    create a multi-dimensional model using the three-dimensional model and the reduced-order blood flow model; and

    determine a value of a fractional flow reserve at each of a plurality of locations within the portion of the anatomical structure using the multi-dimensional model.

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