System for detection and treatment of infection or inflammation

• US 9,237,853 B2
• Filed: 07/01/2010
• Issued: 01/19/2016
• Est. Priority Date: 07/03/2009
• Status: Active Grant

• Current Assignee: ThermoMend International Ltd. (Flex, Ltd.)
• Original Assignee: ThermoMend International Ltd. (Flex, Ltd.)
• Inventors: Dewaegenaere, Levi Emmerik A.
• Primary Examiner(s): Dougherty, Sean
• Assistant Examiner(s): CERIONI, DANIEL LEE
• Application Number:
  US13/261,116
• Publication Number:
  US 20120101403A1
• Time in Patent Office: 2,028 Days
• Field of Search: 374/100, 374/101, 374/102, 374/107, 374/137, 374/141, 374/145, 600/549
• US Class Current: 1/1
• CPC Class Codes: A61B 5/015 By temperature mapping of body part
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/0075 using a Peltier element, e.g. near the spot to be heated or cooled
• CPC Class Codes: A61F 2007/0095 with a temperature indicator
• CPC Class Codes: A61F 7/10 Cooling bags, e.g. ice-bags

Abstract

A system for visualizing a medical treatment of a human or animal body part. The system has means for thermal treatment of the body part, means for determining the temperature distribution on the body part, and means for identifying the location of a particular temperature determined on the body part. Further, a method for visualizing the temperature characteristics of a human or animal body part is provided. The method includes the steps of comparing a first temperature distribution data set of the surface of the body part with a second temperature distribution data set of the surface of the body part, wherein the first temperature distribution data set is determined before and the second temperature distribution data set is determined after a thermal treatment of the body part, and visualizing the temperature distribution data sets of the body part.

Claims

1. A system for displaying a medical treatment of a human or animal body part, comprising:

means for thermal treatment of the body part;

means for determining a temperature distribution, the means for determining a temperature distribution being configured to obtain a first temperature distribution data set of the surface of the body part and a second temperature distribution data set of the surface of the body part, the first temperature distribution data set representing a temperature distribution of the body part before a treatment of the body part, and the second temperature distribution data set representing a temperature distribution of the body part after a treatment has begun on the body part;

a computer programmed to;

determine a 3-D representation of a temperature map signature over a time of thermal treatment where a vertical axis represents a temperature and a horizontal axis represents special coordinates or both axes in the 3-D representation represent special coordinates and the contours represent equi-temperature lines;

compare the first temperature distribution data set to the second temperature distribution data set to determine a rate of change of the temperature distribution of the body part over a period of time;

detect a specific location of the body part that is subject to a condition based on the temperature map signature and the rate of change, wherein the condition is selected from the group consisting of;

inflammation or infection;

compare the rate of change to a database to determine whether the condition is inflammation of infection, the database containing data obtained from thermal treatments of one or more former patients and data from theoretical simulations previously carried out by the computer;

determine that the body part is subject to inflammation when the temperature map signature shows the body part cooling at a first rate and the rate of change being a first rate;

determine that the body part is subject to infection when the temperature map signature shows the body part cooling at a second rate and the rate of change being a second rate;

wherein the second rate is slower than the first rate; and

generating or amending a treatment protocol based on the rate of change; and

means for displaying the temperature distribution, wherein the means for displaying the temperature distribution is configured to display the temperature distribution dependent on the location of the body part and wherein the means for displaying the temperature distribution is configured to provide the 3D representation of the temperature map signature over the time of thermal treatment.

2. The system of claim 1, wherein the computer is adapted to generate the protocol on the basis of the temperature distribution determined.

3. The system of claim 1, wherein the means for thermal treatment of the body part is a patch having fluid communication channels providing the thermal treatment.

4. The system of claim 1, wherein the means for thermal treatment of the body part is a device having a Peltier element providing the thermal treatment.

5. A method, implemented on a system for the detection and treatment of infection or inflammation, for displaying temperature characteristics of a human or animal body part, the method comprising:

using a thermal treatment device having an energy exchange device to perform a thermal treatment of the body part; and

obtaining, using a camera, a first temperature distribution data set of the surface of the body part, the first temperature distribution data set representing a temperature distribution of the body part before a treatment of the body part;

obtaining, using the camera, a second temperature distribution data set of the surface of the body part, the second temperature distribution data set representing a temperature distribution of the body part after a treatment has begun on the body part;

implementing on a computer via a computer program product;

determining a 3-D representation of a temperature map signature over a time of thermal treatment where a vertical axis represents a temperature and a horizontal axis represents special coordinates or both axes in the 3-D representation represent special coordinates and the contours represent equi-temperature lines;

comparing the first temperature distribution data set to the second temperature distribution data set to determine a rate of change of the temperature distribution of the body part over a period of time;

detecting a specific location of the body part that is subject to a condition based on the temperature map signature and the rate of change, wherein the condition is selected from the group consisting of;

inflammation or infection;

comparing the rate of change to a database to determine whether the condition is inflammation or infection, the database containing data obtained from thermal treatments of one or more former patients and data from theoretical simulations previously carried out by the computer;

determining that the body part is subject to inflammation when the temperature map signature shows the body part cooling at a first rate and the rate of change being a first rate;

determining that the body part is subject to infection when the temperature map signature the body part cooling at a second rate and the rate of change being a second rate;

wherein the second rate is slower than the first rate; and

generating or amending a treatment protocol based on the rate of change; and

displaying on a display, the 3-D representation of the temperature map signature over the time of thermal treatment.

6. The method of claim 5, further comprising the steps of:

comparing the first temperature distribution data set of the surface of the body part with the second temperature distribution data set of the surface of the body part, between the first determining step and the displaying step; and

visualizing at least one of the first and second temperature distribution data sets.

7. The method of claim 6, further comprising the step of:

determining a diagnosis of a disease on the basis of a comparison of the data sets.

8. The method of claim 7, wherein the determination of the diagnosis is carried out by calibrating the data sets dependent on known characteristic data sets.

9. The method of claim 8, wherein the treatment protocol is amended on the basis of a comparison of the data sets.

11. The media of claim 9, further comprising:

comparing the first temperature distribution data set of the surface of the body part with the second temperature distribution data set of the surface of the body part, between the first determining step and the displaying step; and

visualizing at least one of the first and second temperature distribution data sets.

12. The media of claim 11, further comprising determining a diagnosis of a disease on the basis of the data sets.

13. The media of claim 12, wherein the determination of the diagnosis is carried out by calibrating the data sets dependent on known characteristic data sets.

14. The media of claim 12, wherein the treatment protocol is amended on the basis of a comparison of the data sets.

10. A non-transitory computer readable information storage media having stored thereon instructions, that when executed by a processor, cause to be performed a method for displaying the temperature characteristics of a human or animal body part, the method comprising:

performing a thermal treatment of the body part using a thermal treatment device having an energy exchange device;

obtaining, using a camera, a first temperature distribution data set of the surface of the body part, the first temperature distribution data set representing a temperature distribution of the body part before a treatment of the body part;

obtaining, using the camera, a second temperature distribution data set of the surface of the body part, the second temperature distribution data set representing a temperature distribution of the body part after a treatment has begun on the body part;

determining a 3-D representation of a temperature map signature over a time of thermal treatment where a vertical axis represents a temperature and a horizontal axis represents special coordinates or both axes in the 3-D representation represent special coordinates and the contours represent equi-temperature lines;

comparing the first temperature distribution data set to the second temperature distribution data set to determine a rate of change of the temperature distribution of the body part over a period of time;

detecting a specific location of the body part that is subject to a condition based on the temperature map signature and the rate of change, wherein the condition is selected from the group consisting of;

inflammation or infection;

comparing the rate of change to a database to determine whether the condition is inflammation or infection, the database containing data obtained from thermal treatments of one or more former patients and data from theoretical simulations previously carried out by the computer;

determining that the body part is subject to inflammation when the temperature map signature shows the body part cooling at a first rate and the rate of change being a first rate;

determining that the body part is subject to infection when the temperature map signature the body part cooling at a second rate and the rate of change being a second rate;

wherein the second rate is slower than the first rate; and

generating or amending a treatment protocol based on the rate of change; and

displaying on a display, the 3-D representation of the temperature map signature over the time of thermal treatment.

15. A system configured to visualize a medical treatment of a human or animal body part, comprising:

a thermal treatment device and energy exchange device to thermally treat the body part;

a camera configured to obtain a first temperature distribution data set of the surface of the body part and a second temperature distribution data set of the surface of the body part, the first temperature distribution data set representing a temperature distribution of the body part before a treatment of the body part, and the second temperature distribution data set representing a temperature distribution of the body part after a treatment has begun on the body part;

a computer programmed to

determine a 3-D representation of a temperature map signature over a time of thermal treatment where a vertical axis represents a temperature and a horizontal axis represents special coordinates or both axes in the 3-D representation represent special coordinates and the contours represent equi-temperature lines;

compare the first temperature distribution data set to the second temperature distribution data set to determine a rate of change of the temperature distribution of the body part over a period of time;

detect a specific location of the body part that is subject to a condition based on the temperature map signature and the rate of change, wherein the condition is selected from the group consisting of;

inflammation or infection;

compare the rate of change to a database to determine whether the condition is inflammation of infection, the database containing data obtained from thermal treatments of one or more former patients and data from theoretical simulations previously carried out by the computer;

determine that the body part is subject to inflammation when the temperature map signature shows the body part cooling at a first rate and the rate of change being a first rate;

determine that the body part is subject to infection when the temperature map signature shows the body part cooling at a second rate and the rate of change being a second rate;

wherein the second rate is slower than the first rate; and

generating or amending a treatment protocol based on the rate of change; and

a display configured to provide the 3-D representation of the temperature map signature over the time of thermal treatment.