Patient interface for ophthalmologic diagnostic and interventional procedures

• US 9,237,967 B2
• Filed: 10/21/2011
• Issued: 01/19/2016
• Est. Priority Date: 10/21/2011
• Status: Active Grant

• Current Assignee: AMO Development LLC (Johnson & Johnson)
• Original Assignee: OptiMedica Corporation (Johnson & Johnson)
• Inventors: Gooding, Phillip, Wiltberger, Michael, Beltran, Christine, Talamo, Jonathan
• Primary Examiner(s): Thomson, William
• Assistant Examiner(s): Downey, John R
• Application Number:
  US13/279,155
• Publication Number:
  US 20130103014A1
• Time in Patent Office: 1,551 Days
• Field of Search: 606 4- 6
• US Class Current: 1/1
• CPC Class Codes: A61B 2090/3937 Visible markers
• CPC Class Codes: A61B 2090/3979 infrared
• CPC Class Codes: A61B 2090/3983 Reference marker arrangements for use with image guided surgery
• CPC Class Codes: A61B 3/0008 provided with illuminating means A61B3/117 takes precedence; goniolenses used for laser treatment A61F9/009; illuminating means for optical instruments G02B27/00
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models
• CPC Class Codes: A61B 3/102 for optical coherence tomography [OCT]
• CPC Class Codes: A61B 3/14 Arrangements specially adapted for eye photography apparatus or arrangements for taking photographs per se G03B
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2009/00851 Optical coherence topography [OCT]
• CPC Class Codes: A61F 2009/0087 Lens
• CPC Class Codes: A61F 2009/00887 Cataract
• CPC Class Codes: A61F 2009/00897 Scanning mechanisms or algorithms
• CPC Class Codes: A61F 9/00814 Laser features or special beam parameters therefor
• CPC Class Codes: A61F 9/00825 for photodisruption
• CPC Class Codes: A61F 9/0084 Laser features or special beam parameters therefor
• CPC Class Codes: A61F 9/009 Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses apparatus for eye examination A61B3/0008

Abstract

An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

Claims

1. A system for ophthalmic intervention on an eye of a patient having temporary geometric markers thereon indicative of the orientation of an astigmatic axis of the patient'"'"'s eye, comprising:

a. an imaging device having a field of view oriented toward the eye of the patient;

b. a patient interface housing having proximal and distal ends and defining a passage therethrough, wherein the distal end is coupled to one or more seals around a periphery of the passage configured to be directly engaged with an exterior surface of the eye of the patient and having a size sufficient render visible the temporary geometric markers on the eye in that the temporary geometric markers are within the field of view of the imaging device, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage;

c. two discrete, diametrically-opposed registration fiducials formed on an inner annulus of the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to the temporary geometric markers on the eye of the patient;

d. a third registration fiducial formed on the inner annulus of the patient interface housing within the field of view of the imaging device such that it may be imaged by the imaging device, the third registration fiducial being angularly spaced from the two discrete, diametrically-opposed registration fiducials; and

e. control electronics operatively coupled with the image device and configured to process image data generated via the image device for the registration fiducials and the temporary geometric markers on the eye of the patient so as to determine an angular orientation of the eye relative to the patient interface housing, the control electronics further being configured to determine an up or down orientation of the patient interface housing relative to the eye based on the location of the third registration fiducial.

2. The system of claim 1, further comprising a laser system operatively coupled to the control electronics.

3. The system of claim 2, wherein the laser system is configured to produce a treatment beam that may be directed through the passage of the patient interface housing and into the eye of the patient.

4. The system of claim 3, wherein the treatment beam is suitable for creating dielectric breakdown within a cataractous crystalline lens of the eye.

5. The system of claim 4, wherein the laser system is configured to produce a pulsed treatment beam with a pulse repetition rate between about 1 kHz and about 200 kHz.

6. The system of claim 4, wherein the laser system is configured to produce a treatment beam having a wavelength between about 800 nm and about 1,100 nm.

7. The system of claim 4, wherein the laser system is configured to produce a pulsed treatment beam having a pulse energy between about 1 microjoule and about 1,000 microjoules.

8. The system of claim 4, wherein the laser system is configured to produce a pulsed treatment beam with a pulse duration between about 100 femtoseconds and about 10 picoseconds.

9. The system of claim 1, further comprising an optical lens coupled to the housing and having a focal axis aligned to pass through the passage of the housing.

10. The system of claim 1, wherein further comprising an illumination source configured to direct illumination radiation from a position adjacent the imaging device toward the eye of the patient.

11. The system of claim 1, wherein an illumination source is configured to direct illumination radiation through the passage of the patient interface housing.

12. The system of claim 1, wherein at least a portion of the patient interface housing is at least partially translucent to illumination radiation, and wherein an illumination source is configured to direct at least a portion of the illumination radiation across the translucent portion of the patient interface housing toward the eye of the patient.

13. The system of claim 10, wherein the illumination radiation is infrared radiation.

14. The system of claim 10, wherein the illumination radiation is visible light radiation.

15. The system of claim 1, wherein the imaging device comprises an optical coherence tomography system configured to measure the coherence of radiation scattered into an interferometer from the field of view.

16. The system of claim 13, wherein the fiducials comprise one or more materials that fluoresce in infrared radiation.

17. The system of claim 13, wherein the fiducials comprise one or more materials that highly contrast in infrared radiation relative to other surrounding materials.

18. The system of claim 1, wherein the fiducials comprise one or more surface irregularities relative to other surrounding surfaces.

19. The system of claim 18, wherein the one or more surface irregularities are selected from the group consisting of:

a concave feature, a convex feature, a depressed edge, a depressed step, a projecting edge, a projecting step, and an intersection of lines.

20. The system of claim 14, wherein the fiducials comprise one or more materials that highly contrast in visible light radiation relative to other surrounding materials.

21. The system of claim 14, wherein the fiducials comprise one or more surface irregularities relative to other surrounding surfaces.

22. The system of claim 21, wherein the one or more surface irregularities are selected from the group consisting of:

a concave feature, a convex feature, a depressed edge, a depressed step, a projecting edge, a projecting step, and an intersection of lines.

23. The system of claim 15, wherein the fiducials comprise one or more surface irregularities relative to other surrounding surfaces.

24. The system of claim 23, wherein the one or more surface irregularities are selected from the group consisting of:

a concave feature, a convex feature, a depressed edge, a depressed step, a projecting edge, a projecting step, and an intersection of lines.

25. The system of claim 1, wherein the fiducials are positioned adjacent the distal end of the patient interface housing.

26. The system of claim 25, wherein the third fiducial is positioned 90°

from the first two fiducials.

27. The system of claim 1, wherein:

the control electronics are configured to process the image data generated via the imaging device to determine angular orientation of the astigmatic axis of the patient'"'"'s eye relative to the patient interface housing.

28. The system of claim 1, wherein the image data generated via the image device includes data regarding three-dimensional positions of the registration fiducials and of anatomical features of the patient'"'"'s eye.

29. The system of claim 1, wherein the patient interface housing includes a top part coupled to a bottom part, wherein the top part houses an optical lens in the field of view of the imaging device and through which the imaging device views a bottom part having the fiducials, and wherein a space between the top and bottom parts defines a liquid chamber that when filled with liquid provides an optical interface between the eye and a lower surface of the optical lens, and wherein the fiducials are located in the liquid chamber.