Botulinum toxin treatment of anxiety and bipolar disorders
First Claim
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1. A method for treating an anxiety disorder in a patient in need thereof, comprising directly administering a botulinum toxin to a trigeminal nerve of the patient, thereby treating the anxiety disorder.
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Abstract
Methods for preventing or treating depression including a depression mediated by the thalamus. Depression, including a thalamically mediated depression, can be treated by peripheral administration of a botulinum toxin to or to the vicinity of a trigeminal sensory nerve, thereby preventing or treating the depression.
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20 Claims
- 1. A method for treating an anxiety disorder in a patient in need thereof, comprising directly administering a botulinum toxin to a trigeminal nerve of the patient, thereby treating the anxiety disorder.
- 8. A method for reducing the occurrence of a symptom of anxiety disorder in a patient with anxiety disorder, the method comprising locally administering a therapeutically effective amount of a botulinum toxin non-intramuscularly to a trigeminal sensory nerve or to the vicinity of a trigeminal sensory nerve of the patient, thereby reducing the occurrence of a symptom of anxiety disorder, wherein the administering is subdermal, intradermal or transdermal.
- 16. A method for treating bipolar disorder in a patient in need thereof, comprising locally administering a botulinum toxin non-intramuscularly to a trigeminal nerve of the patient, thereby treating the bipolar disorder, wherein the administering is subdermal, intradermal or transdermal.
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