Low profile actuator and improved method of caregiver controlled administration of therapeutics

• US 9,238,102 B2
• Filed: 09/10/2010
• Issued: 01/19/2016
• Est. Priority Date: 09/10/2009
• Status: Active Grant

• Current Assignee: Medipacs, Inc.
• Original Assignee: Medipacs, Inc.
• Inventors: Banister, Mark, Bloom, William G., Geronov, Yordan M., McWilliams, Mark D., Swenson, David, Van Veen, Mark A.
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Hall, Deanna K
• Application Number:
  US13/395,627
• Publication Number:
  US 20120191060A1
• Time in Patent Office: 1,957 Days
• Field of Search: 604/131, 604/66
• US Class Current: 1/1
• CPC Class Codes: A61M 2205/0272 Electro-active or magneto-active materials
• CPC Class Codes: A61M 2205/0277 Chemo-active materials
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 2230/202 partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: A61M 2230/42 Rate
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/148 flexible, e.g. independent bagsA61M5/155 takes precedence
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A polymer actuator, power supply and method of using the activation are described.

Claims

1. A low profile medication delivery device comprising:

a chassis having a first dimension X, a second dimension Y orthogonal to the first dimension X, and a third dimension Z orthogonal to both first dimension X and second dimension Y, wherein the first dimension X and the second dimension X form a plane, and wherein the chassis has a first pocket and a second pocket;

an actuator assembly overlaying a plurality of collapsible reservoirs disposed within the first pocket; and

electronics disposed within the second pocket and coupled to the actuator assembly, the actuator assembly being configured to separately control expansion and compression of each collapsible reservoir in response to current being passed through the actuator assembly.

2. The low profile medication delivery device of claim 1,

wherein the actuator assembly includes an upper electrode, a lower electrode, and a polymeric actuator between the upper electrode and the lower electrode;

and wherein the actuator assembly optionally further includes;

a sealed flexible outer housing surrounding the upper electrode, the lower electrode, and the polymeric actuator; and

an electrolyte solution within the housing and in contact with the polymeric actuator, wherein the polymeric actuator is configured to expand in response to pH changes in the electrolyte solution induced by the current, wherein one of the electrodes preferably is surrounded, at least in part, by a porous separator membrane that facilitates modulation of the pH via charges separation.

3. The low profile medication delivery device of claim 1, further comprising:

an upper support adjacent to the upper electrode; and

a lower support adjacent the collapsible reservoir, wherein the lower electrode is adjacent to the collapsible reservoir and is configured to function as a piston plate that compresses the collapsible reservoir between the lower support and the lower electrode as the polymeric actuator expands.

4. The low profile medication delivery device of claim 1, further comprising:

an upper support adjacent to the upper electrode;

a lower support adjacent the plurality of collapsible reservoirs; and

a piston plate disposed between the lower electrode and the plurality of collapsible reservoirs.

5. The low profile medication delivery device of claim 1, further comprising:

wherein the chassis has a third pocket, and further comprising a second actuator assembly overlaying a second collapsible reservoir disposed within the third pocket.

6. The low profile medication delivery device of claim 1, further comprising:

wherein at least two but not all of the collapsible reservoirs are configured to be simultaneously pressurized by the actuator when current is passed through the actuator.

7. The low profile medication delivery device of claim 1, further comprising:

wherein the chassis has a length defined along a primary lateral axis, a width defined along a secondary lateral axis, and a depth defined along a depth axis, the chassis having a first pocket and a second pocket arranged and separated along the primary lateral axis to minimize the depth, the length greater than the width, the width greater than the depth;

the actuator assembly overlaying the plurality of collapsible reservoirs disposed within the first pocket; and

electrical leads coupling the electronics to the actuator assembly.

8. The low profile medication delivery device of claim 7, further comprising:

wherein the actuator assembly expands along the depth axis in response to charge passed from the electronics to the actuator;

the actuator assembly includes a polymeric actuator that expands in response to pH changes within the actuator assembly, and the electronics are configured to deliver current to the actuator assembly that modulates the pH; and

the primary lateral axis, the secondary lateral axis, and the depth axis are mutually perpendicular.

9. The low profile medication delivery device of claim 1, further comprising:

further comprising;

a lower support;

an upper support fixedly coupled to the lower support;

a collapsible fluid reservoir positioned adjacent to the lower support;

an actuator assembly positioned between the collapsible fluid reservoir and the upper support, the actuator assembly including;

an upper electrode proximate the upper support; and

a polymeric actuator positioned adjacent to the upper electrode; and

a piston plate positioned between the polymeric actuator and the collapsible fluid reservoir.

10. The low profile medication delivery device of claim 9, further comprising:

wherein the polymeric actuator is configured to change dimensionally in response to pH changes within the actuator assembly;

the piston plate is a lower electrode within the actuator assembly;

the actuator assembly includes a lower electrode that is proximate to the piston plate; and

the upper electrode has a first area, the piston plate has a second area that is larger than the first area to maximize volumetric efficiency of the low profile medication delivery apparatus.

11. The low profile medication delivery device of claim 10, further comprising:

(v) further comprising a housing having mutually orthogonal axes including a major lateral axis having a first dimension, a minor lateral axis having a second dimension, and a depth axis having a third dimension, the housing enclosing two pockets that are arranged along the major lateral axis including a first pocket and a second pocket, the actuator assembly overlaying the plurality of collapsible reservoirs within the first pocket, the depth axis less than either the first dimension or the second dimension, wherein the second pocket optionally contains electronics coupled to the actuator assembly and configured to deliver current to the actuator assembly, the actuator assembly configured to increase a dimension in the depth axis and to compress the plurality of collapsible reservoirs in response to the current.

12. A low profile medication delivery device comprising:

a chassis having a first dimension X, a second dimension Y orthogonal to the first dimension X, and a third dimension Z orthogonal to both first dimension X and second dimension Y, wherein the first dimension X and the second dimension Y form a plane, and wherein the chassis has a first pocket and a second pocket;

an actuator assembly including a rigid electrode which functions as a rigid platen overlaying a collapsible reservoir disposed within the first pocket; and

electronics disposed within the second pocket and coupled to the actuator assembly, the actuator assembly being configured to control expansion and compression of the collapsible reservoir in response to current being passed through the actuator assembly.

13. The low profile medication delivery device of claim 12,

wherein the actuator assembly includes an upper electrode, a lower electrode, and a polymeric actuator between the upper electrode and the lower electrode;

and wherein the actuator assembly optionally further includes;

a sealed flexible outer housing surrounding the upper electrode, the lower electrode, and the polymeric actuator; and

an electrolyte solution within the housing and in contact with the polymeric actuator, wherein the polymeric actuator is configured to expand in response to pH changes in the electrolyte solution induced by the current, wherein one of the electrodes preferably is surrounded, at least in part, by a porous separator membrane that facilitates modulation of the pH via charges separation.

14. The low profile medication delivery device of claim 12, further comprising:

an upper support adjacent to the upper electrode; and

a lower support adjacent the collapsible reservoir, wherein the lower electrode is adjacent to the collapsible reservoir and is configured to function as a piston plate that compresses the collapsible reservoir between the lower support and the lower electrode as the polymeric actuator expands.

15. The low profile medication delivery device of claim 12, further comprising:

an upper support adjacent to the upper electrode;

a lower support adjacent the collapsible reservoir; and

a piston plate disposed between the lower electrode and the collapsible reservoir.

16. The low profile medication delivery device of claim 12, further comprising:

wherein the chassis has a third pocket, and further comprising a second actuator assembly overlaying a second collapsible reservoir disposed within the third pocket.

17. The low profile medication delivery device of claim 12, further comprising:

wherein at least two collapsible reservoirs configured to be simultaneously pressurized by the actuator when current is passed through the actuator.

18. The low profile medication delivery device of claim 12, further comprising:

wherein the chassis has a length defined along a primary lateral axis, a width defined along a secondary lateral axis, and a depth defined along a depth axis, the chassis having a first pocket and a second pocket arranged and separated along the primary lateral axis to minimize the depth, the length greater than the width, the width greater than the depth;

the actuator assembly overlaying collapsible reservoir disposed within the first pocket; and

electrical leads coupling the electronics to the actuator assembly.

19. The low profile medication delivery device of claim 18, further comprising:

wherein the actuator assembly expands along the depth axis in response to charge passed from the electronics to the actuator;

the actuator assembly includes a polymeric actuator that expands in response to pH changes within the actuator assembly, and the electronics are configured to deliver current to the actuator assembly that modulates the pH; and

the primary lateral axis, the secondary lateral axis, and the depth axis are mutually perpendicular.

20. The low profile medication delivery device of claim 12, further comprising:

further comprising;

a lower support;

an upper support fixedly coupled to the lower support;

a collapsible fluid reservoir positioned adjacent to the lower support;

an actuator assembly positioned between the collapsible fluid reservoir and the upper support, the actuator assembly including;

an upper electrode proximate the upper support; and

a polymeric actuator positioned adjacent to the upper electrode; and

a piston plate positioned between the polymeric actuator and the collapsible fluid reservoir.

21. The low profile medication delivery device of claim 20, further comprising:

wherein the polymeric actuator is configured to change dimensionally in response to pH changes within the actuator assembly;

the piston plate is a lower electrode within the actuator assembly;

the actuator assembly includes a lower electrode that is proximate to the piston plate; and

the upper electrode has a first area, the piston plate has a second area that is larger than the first area to maximize volumetric efficiency of the low profile medication delivery apparatus.

22. The low profile medication delivery device of claim 21, further comprising:

(v) further comprising a housing having mutually orthogonal axes including a major lateral axis having a first dimension, a minor lateral axis having a second dimension, and a depth axis having a third dimension, the housing enclosing two pockets that are arranged along the major lateral axis including a first pocket and a second pocket, the actuator assembly overlaying the collapsible reservoir within the first pocket, the depth axis less than either the first dimension or the second dimension, wherein the second pocket optionally contains electronics coupled to the actuator assembly and configured to deliver current to the actuator assembly, the actuator assembly configured to increase a dimension in the depth axis and to compress the collapsible reservoir in response to the current.