Medicament delivery device having an electronic circuit system

• US 9,238,108 B2
• Filed: 07/17/2012
• Issued: 01/19/2016
• Est. Priority Date: 02/01/2005
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Kaleo, Inc.
• Inventors: Edwards, Eric S., Edwards, Evan T., Licata, Mark J., Meyers, Paul F., Weinzierl, David A.
• Primary Examiner(s): SCHMIDT, EMILY LOUISE
• Application Number:
  US13/550,893
• Publication Number:
  US 20130190692A1
• Time in Patent Office: 1,281 Days
• Field of Search: 604/92, 604/131, 604/189, 604/890, 604/1, 604/890.1
• US Class Current: 1/1
• CPC Class Codes: A61M 15/0001 Details of inhalators; Constructional features thereof
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/584 having a color code
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 2205/6027 Electric-conductive bridges closing detection circuits, with or without identifying elements, e.g. resistances, zener-diodes
• CPC Class Codes: A61M 2205/6063 Optical identification systems
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31 Details
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3287 Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: A61M 5/5086 for indicating if defective, used, tampered with or unsterile
• CPC Class Codes: G09B 23/28 : for medicine
• CPC Class Codes: G09B 23/285 : for injections, endoscopy, bronchoscopy, sigmoidscopy, insertion of contraceptive devices or enemas
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection

Abstract

Medicament delivery devices are described herein. In some embodiments, an apparatus includes a medical injector and an electronic circuit system. The medical injector includes a housing, a medicament container, and a medicament delivery member. The housing defines a first region and a second region. The first region includes the medicament container and is physically isolated from the second region. The electronic circuit system is configured to be disposed within the second region defined by the housing. The electronic circuit system is configured to output an electronic output associated with a use of the medical injector.

Claims

1. An apparatus comprising:

a medicament delivery device configured to deliver a medicament, the medicament delivery device having a first housing, an energy storage member, and a medicament container, the energy storage member configured to produce a force to move the medicament container within the first housing, an exterior wall of the first housing defining an interior volume, at least one of the energy storage member or the medicament container completely disposed within the interior volume;

a second housing formed separately from the first housing, the second housing including a connection portion configured to be matingly coupled to a corresponding connection portion of the first housing such that an interface between the exterior wall of the first housing and the second housing is substantially flush and such that the second housing remains in a fixed position relative to the first housing during a delivery event; and

an electric circuit system having an audible output device coupled to the second housing, the electronic circuit system configured to produce a recorded speech output via the audible output device when the electronic circuit system is actuated.

2. The apparatus of claim 1, wherein:

the second housing is configured to be coupled to the first housing such that the second housing covers a first opening defined by the first housing; and

the first housing defines a second opening configured to be at least partially aligned with the medicament container, the second housing configured to be coupled to the first housing such that the second opening is unobstructed by the second housing.

3. The apparatus of claim 1, wherein the exterior wall is a first wall, the first housing of the medicament delivery device further including a second wall that separates the interior volume of the first housing into a first cavity and a second cavity, the audible output device at least partially disposed within the first cavity when the second housing is coupled to the first housing, the medicament container configured to move within the second cavity.

4. The apparatus of claim 1, wherein:

the first housing defines, at least in part, a cavity;

the second housing is configured to be coupled to the first housing such that the second housing covers a first opening defined by the first housing, the first opening in fluid communication with the cavity;

the audible output device is at least partially disposed within the cavity when the second housing is coupled to the first housing; and

the first housing defines a second opening configured to allow visual access to the medicament container within the interior volume.

5. The apparatus of claim 1, wherein the audible output device has a first side and a second side, the audible output device is coupled to the second housing such that the first side is aligned with a plurality of sound openings defined by the second housing, the first side of the audible output device is configured to emit sound through the plurality of sound openings, the second side of the audible output device is configured to emit sound into an enclosure defined, at least in part, by the first housing.

6. The apparatus of claim 1, wherein the medicament delivery device includes a needle configured to be placed in fluid communication with the medicament container.

7. The apparatus of claim 1, wherein:

the electronic circuit system includes a printed circuit board disposed within a cavity defined, at least in part, by the first housing,

the audible output device is spaced apart from the printed circuit board; and

the audible output device is electrically coupled to the printed circuit board via a wire.

8. The apparatus of claim 1, wherein:

the audible output device is coupled to the second housing such that a first side of the audible output device is aligned with a plurality of sound openings defined by the second housing, the first side of the audible output device is configured to emit sound through the plurality of sound openings to an exterior volume, a second side of the audible output device is configured to emit sound into an enclosure defined, at least in part, by the first housing.

9. The apparatus of claim 1, wherein:

the second housing is configured to be coupled to the first housing such that the second housing covers an opening defined by the first housing; and

the second housing has a shape matching a shape of the opening.

10. The apparatus of claim 1, wherein the energy storage member is a non-electronic energy storage member configured to produce the force to deliver the medicament independently from the operation of electronic circuit system.

11. The apparatus of claim 1, wherein:

the electronic circuit system includes a printed circuit board disposed within a cavity defined, at least in part, by the first housing, the printed circuit board including a switch configured to actuate the electronic circuit system when moved from a first state to a second state; and

the medicament delivery device includes an actuator coupled to the first housing, the actuator including a protrusion configured to engage the switch when the actuator is actuated.

13. The apparatus of claim 1, wherein a cross section of the exterior wall defines a perimeter completely surrounding the at least one of the energy storage member or the medicament container.

12. The apparatus of 11, wherein the protrusion is configured to be aligned with the switch.

14. An apparatus comprising:

a medicament delivery device configured to deliver a medicament, the medicament delivery device including a medicament container, an energy storage member configured to produce a force to deliver the medicament, and a housing defining a cavity;

an actuator configured to cause the energy storage member to produce the force to deliver the medicament;

an electronic circuit system having a speaker configured to be disposed within the cavity, the electronic circuit system configured to produce a recorded speech output via the speaker when the electronic circuit system is actuated, the speaker coupled to a speaker member configured to cover the cavity, the electronic circuit system including a battery configured to be electrically coupled to the speaker; and

a cover removeably coupled to the medicament delivery device and configured to limit movement of the actuator, the cover having a battery isolation member configured to protrude into the cavity to electrically decouple the battery from the speaker when the cover is coupled to the medicament delivery device, the battery isolation member spaced apart from the battery such that the battery is electrically coupled to the speaker when the cover is removed from the medicament delivery device.

15. The apparatus of claim 14, wherein:

a portion of the housing defining the cavity defines a first opening, the housing defines a second opening and a third opening, the second opening and the third opening each configured to be at least partially aligned with the medicament container to allow visual access to the medicament container, the third opening on an opposite side of the housing from the second opening, the speaker member configured to be coupled to the housing such that the first opening is covered by the speaker member and each of the second opening and the third opening is unobstructed by the speaker member.

16. The apparatus of claim 14, wherein:

the cavity is a first cavity;

the housing defines a second cavity and includes a wall separating the first cavity and the second cavity;

the speaker is at least partially disposed within the first cavity when the speaker member is coupled to the housing; and

the medicament container is disposed within the second cavity.

17. The apparatus of claim 14, wherein:

the cavity is a first cavity;

the housing defines a second cavity and includes a wall separating the first cavity and the second cavity, the medicament container is disposed within the second cavity;

the speaker is at least partially disposed within the first cavity when the speaker member is coupled to the housing; and

the housing defines an opening configured to allow visual access to the medicament container within the second cavity.

18. The apparatus of claim 14, wherein the energy storage member is a non-electronic energy storage member configured to produce the force to deliver the medicament independently from the operation of electronic circuit system.

19. The apparatus of claim 14, wherein the electronic circuit system is coupled to the speaker member.

20. The apparatus of claim 14 wherein the speaker member includes a connection protrusion configured to be received within a connection opening defined by the housing to fixedly couple the speaker member to the housing such that an interface between the first housing and the speaker member defines a continuous surface.