Compositions, devices, kits and methods for detecting hookworm
First Claim
1. A method of detecting the presence or absence of one or more hookworm coproantigens in a fecal sample of a mammal, said method comprising:
- (a) contacting the fecal sample with one or more antibodies that can specifically bind to CoproASP5; and
(b) detecting the presence or absence of the one or more hookworm coproantigens or detecting the presence or absence of one or more complexes that include the one or more hookworm coproantigens and the one or more antibodies using a labeled secondary antibody.
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Accused Products
Abstract
Methods, devices, kits and compositions for detecting the presence or absence of hookworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of hookworm in a fecal sample from a mammal that may also be infected with one or more of roundworm, whipworm, and heartworm. Confirmation of the presence or absence of hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
60 Citations
23 Claims
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1. A method of detecting the presence or absence of one or more hookworm coproantigens in a fecal sample of a mammal, said method comprising:
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(a) contacting the fecal sample with one or more antibodies that can specifically bind to CoproASP5; and (b) detecting the presence or absence of the one or more hookworm coproantigens or detecting the presence or absence of one or more complexes that include the one or more hookworm coproantigens and the one or more antibodies using a labeled secondary antibody. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 22)
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12. A method of diagnosing an intestinal hookworm infection in a mammal, the method comprising the steps of:
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(a) obtaining a fecal sample from the mammal (b) contacting the sample from the mammal with one or more antibodies that can specifically bind to CoproASP5; (c) detecting the presence or absence of the one or more hookworm coproantigens or detecting the presence or absence of one or more complexes that include the one or more hookworm coproantigens and the one or more antibodies using a labeled secondary antibody; and (d) diagnosing the mammal as having or as not having the hookworm infection based on the detection of the presence or absence of the one or more hookworm coproantigens or the one or more complexes. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 23)
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Specification