Combination treatment selection methods and systems

• US 9,239,906 B2
• Filed: 05/08/2009
• Issued: 01/19/2016
• Est. Priority Date: 04/24/2008
• Status: Active Grant

• Current Assignee: Harvest Bio LLC, The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Hyde, Roderick A., Ishikawa, Muriel Y., Leuthardt, Eric C., Levien, Royce A., Lord, Robert W., Malamud, Mark A., Sweeney, Elizabeth A., Wood, Lowell L. Jr., Wood, Victoria Y. H.
• Primary Examiner(s): Fleurantin, Jean B
• Application Number:
  US12/387,961
• Publication Number:
  US 20090292676A1
• Time in Patent Office: 2,447 Days
• Field of Search: 707600-831, 600/301, 702/19
• US Class Current: 1/1
• CPC Class Codes: G06F 16/951 Indexing; Web crawling techniques
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients

Abstract

Methods, computer program products, and systems are described that include accepting at least one attribute of at least one individual, querying at least one database at least partly based on the at least one attribute, selecting from the at least one database at least one bioactive agent and at least one artificial sensory experience to address the at least one attribute of at least one individual, and/or presenting an indication of the at least one bioactive agent and the at least one artificial sensory experience at least partly based on the selecting from the at least one database at least one bioactive agent and at least one artificial sensory experience to address the at least one attribute of at least one individual.

Claims

1. A system including hardware comprising:

circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual;

circuitry configured for querying at least one database at least partly based on the at least one mental attribute;

circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual; and

circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.

2. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one stress attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual.

3. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one memory attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual.

4. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one mental impairment of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual.

5. The system of claim 1, wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one memory-dampening agent to address the at least one mental attribute of the at least one individual.

6. The system of claim 1, wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for selecting from the at least one database at least one virtual experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual.

7. The system of claim 1, wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for selecting from the at least one database at least one of the following types of artificial sensory experiences for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual;

an artificial memory scene, a visual narrative, a virtual world, a social networking website, an online game, an online educational experience, a networked game, or a single-player game.

8. The system of claim 1, wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for selecting from the at least one database at least one artificial sensory experience, based on a treatment algorithm, for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual.

9. The system of claim 1, wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at a staggered time relative to administration of the at least one bioactive agent, at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.

10. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one indication of anxiety of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual.

11. The system of claim 1, wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for implementing the at least one artificial sensory experience including at least modifying one or more user interfaces of at least one application on the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.

12. The system of claim 1, further comprising:

circuitry configured for monitoring one or more interpersonal interactions using the at least one mobile device of the at least one individual.

13. The system of claim 12, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one indication of depression of the at least one individual based at least partly on one or more monitored interpersonal interactions using the at least one mobile device of the at least one individual.

14. The system of claim 13, wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for selecting from the at least one database, based at least partly on geographic information associated with the at least one individual, at least one artificial sensory experience for use in combination with at least one anti-depressant agent to address the at least one indication of depression of the at least one individual.

15. The system of claim 14, wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual comprises:

circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile phone device at one or more staggered times relative to administration of the at least one anti-depressant agent based at least partly on one or more pharmacokinetic profiles of the at least one anti-depressant agent, at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one indication of depression of the at least one individual.

16. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one indication of anxiety of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual,

wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for selecting from the at least one database at least one virtual experience for use in combination with at least one anxiolytic agent to address the at least one indication of anxiety of the at least one individual, and

wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for implementing the at least one virtual experience using at least one graphical user interface of the at least one mobile device to address the at least one indication of anxiety of the at least one individual.

17. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one indication of at least one mood disorder of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual,

wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for selecting from the at least one database at least one user interface modification for use in combination with at least one mood stabilizer agent to address the at least one mood disorder of the at least one individual,

wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for implementing the at least one user interface modification using at least one graphical user interface of the at least one mobile device to address the at least one mood disorder of the at least one individual.

18. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one indication of at least one psychotic disorder of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual,

wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for selecting from the at least one database at least one visual experience for use in combination with at least one antipsychotic agent to address the at least one psychotic disorder of the at least one individual, and

wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for implementing the at least one visual experience using at least one graphical user interface of the at least one mobile device to address the at least one psychotic disorder of the at least one individual.

19. The system of claim 1, further comprising:

circuitry configured for accepting at least one indication of appearance of the at least one individual; and

circuitry configured for accepting at least one indication of body movement associated with the at least one individual,

wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual includes, but is not limited to, circuitry configured for accepting at least one indication of depression of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual, at least one indication of appearance of the at least one individual, and the at least one indication of body movement of the individual.

20. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for accepting at least one memory attribute of at least one individual based at least partly on one or more audio recordings associated with usage of at least one mobile device by the at least one individual,

wherein the circuitry configured for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for selecting from the at least one database at least one virtual world experience usable to elicit at least one memory in the at least one individual and usable in combination with at least one memory-dampening agent to address the at least one memory attribute of the at least one individual, and

wherein the circuitry configured for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual includes, but is not limited to, circuitry configured for implementing the at least one virtual world experience using at least one graphical user interface of the at least one mobile device to elicit the at least one memory in the at least one individual at one or more specified times relative to administration of the at least one memory-dampening agent.

21. The system of claim 1, wherein the circuitry configured for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual comprises:

circuitry configured for detecting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual.

22. The system of claim 1, further comprising:

circuitry configured for administering the at least one bioactive agent at one or more staggered times relative to implementation of the at least one artificial sensory experience based at least partly on one or more specified effects of the at least one bioactive agent to address the at least one mental attribute of the at least one individual.

23. A system comprising:

means for accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual;

means for querying at least one database at least partly based on the at least one mental attribute;

means for selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual; and

means for implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.

24. A method implemented using one or more computer processing components, the method comprising:

accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual;

querying at least one database at least partly based on the at least one mental attribute;

selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual; and

implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.

25. A system comprising:

at least one memory comprising one or more executable instructions;

at least one processor operably connected to the at least one memory, wherein the at least one processor is configured to execute the one or more executable instructions to effectuate operations including at least;

accepting at least one mental attribute of at least one individual based at least partly on monitored usage of at least one mobile device by the at least one individual;

querying at least one database at least partly based on the at least one mental attribute;

selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual; and

implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.

26. A system comprising:

a mobile phone device; and

one or more non-transitory storage media bearing one or more instructions that when executed on the mobile phone device cause the mobile phone device to perform operations including at least;

accepting at least one mental attribute of at least one individual based at least partly on monitored usage of the mobile phone device by the at least one individual;

querying at least one database at least partly based on the at least one mental attribute;

selecting from the at least one database at least one artificial sensory experience for use in combination with at least one bioactive agent to address the at least one mental attribute of the at least one individual; and

implementing the at least one artificial sensory experience using at least one graphical user interface of the at least one mobile phone device at least partly based on selection from the at least one database of the at least one artificial sensory experience to address the at least one mental attribute of the at least one individual.