Tools for use in esophagus

• US 9,241,614 B2
• Filed: 08/01/2006
• Issued: 01/26/2016
• Est. Priority Date: 08/01/2005
• Status: Active Grant

• Current Assignee: G.I. View Ltd.
• Original Assignee: G.I. View Ltd.
• Inventors: Goldwasser, Benad, Cabiri, Oz, Gross, Yossi, Lewkowicz, Shlomo
• Primary Examiner(s): Nguyen, Anhtuan T
• Assistant Examiner(s): NEWTON, ALEXANDRA L
• Application Number:
  US11/997,684
• Publication Number:
  US 20110092765A1
• Time in Patent Office: 3,465 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 1/00148 using anchoring means
• CPC Class Codes: A61B 1/04 combined with photographic or television appliances
• CPC Class Codes: A61B 10/0266 means for severing sample
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 10/04 Endoscopic instruments
• CPC Class Codes: A61B 2010/0061 Alimentary tract secretions, e.g. biliary, gastric, intestinal, pancreatic secretions
• CPC Class Codes: A61B 5/064 using markers A61B5/062 takes precedence
• CPC Class Codes: A61B 5/6882 Anchoring means

Abstract

Apparatus (10) is provided, including an elongate carrier (24), configured to be advanced through an esophagus (20) of a subject. An anchor member (30) is coupled to a distal end of the carrier, and configured to be mounted in a stomach (32) of the subject in a vicinity of a lower esophageal sphincter (LES) (34) of the subject. An imaging capsule (26) is configured to move with respect to the carrier when the anchor member is in the vicinity of the LES. Other embodiments are also described.

Claims

1. Apparatus for imaging the esophagus of a subject, comprising:

an anchor member comprising an inflatable anchor member so dimensioned as to have a lateral diameter less than the diameter of the lower esophageal sphincter (LES) of the subject when deflated and having a lateral diameter greater than the diameter of the LES of the subject when inflated, said anchor member being configured to pass through the LES of the subject into the subject'"'"'s stomach and form a pressure seal with the LES upon inflation thereof;

an elongate carrier, configured to be advanced through the esophagus of the subject to the stomach of the subject, and comprising an anchor fluid supply tube, the distal end of which extends into the anchor member for supplying fluid pressure from a fluid pressure source to inflate the anchor member;

an imaging capsule, configured to move along the carrier when the anchor member is in the vicinity of the LES;

a piston head coupled to the imaging capsule configured to form a pressure seal with a wall of the esophagus upon inflation thereof to thereby allow moving the imaging capsule along the carrier in response to fluid pressure applied to a volume of the esophagus external to the apparatus between the piston head and the anchor member, said piston head being configured to travel proximally through the esophagus from the LES to the mouth of the subject in response to pressure from a fluid pressure source delivered to the volume of the esophagus between said piston head and said anchor member; and

a fluid supply tube for supplying fluid pressure to the volume of the esophagus between said piston head and said anchor member when in use.

2. The apparatus according to claim 1, wherein the imaging capsule comprises a sample collection unit, configured to retrieve a sample fluid or tissue of the esophagus by at least one of suction and a cutting instrument provided via an opening provided therein.

3. The apparatus according to claim 1, wherein the apparatus comprises a sample collection unit coupled to the carrier and not an integral portion of the imaging capsule, wherein the collection unit is configured to sample fluid or tissue of the esophagus.

4. The apparatus according to claim 1, wherein the imaging capsule is shaped to define a bore thereof, and wherein the carrier is configured to pass through the bore to allow the imaging capsule to move with respect to the carrier.

5. The apparatus according to claim 1, wherein

the imaging capsule is configured to travel along the carrier, and wherein the imaging capsule comprises:

an optical imaging element.

6. The apparatus according to claim 5, wherein the imaging capsule comprises a sample collection unit, configured to retrieve a sample fluid or tissue of the esophagus by at least one of suction and a cutting instrument provided via an opening provided therein.

7. The apparatus according to claim 5, wherein the apparatus comprises a sample collection unit coupled to the carrier and not an integral portion of the imaging capsule, wherein the collection unit is configured to sample fluid or tissue of the esophagus.

8. The apparatus according to claim 1, comprising at least one wire configured to move the imaging capsule with respect to the carrier when the anchor member is in the vicinity of the LES.

9. The apparatus according to claim 8, comprising one or more pulleys to facilitate movement of the imaging capsule along the carrier via the at least one wire.

10. The apparatus according to claim 1, comprising a tube for moving the imaging capsule with respect to the elongate carrier.

11. A method for imaging the esophagus of a subject using the apparatus of claim 1, comprising:

advancing said elongate carrier through an esophagus of a subject;

mounting in the stomach of the subject in the vicinity of the lower esophageal sphincter (LES) of the subject said anchor member that is coupled to the distal end of said carrier; and

moving said imaging capsule with respect to said carrier when said anchor member is in the vicinity of the LES.

12. The method according to claim 11, wherein said imaging capsule applies a treatment to the esophagus.

13. The method according to claim 11, wherein the imaging capsule comprises a sample collection unit, configured to retrieve a sample fluid or tissue of the esophagus by at least one of suction and a cutting instrument provided via an opening provided therein, and further comprising comprising sampling fluid or tissue of the esophagus by the sample collection unit of the imaging capsule.

14. The method according to claim 11, wherein the imaging capsule is shaped to define a bore thereof, and comprising placing the elongate carrier within the bore of the imaging capsule.

15. The method according to claim 11, wherein mounting the anchor member comprises inflating the anchor member when it is in the stomach.

16. The method according to claim 11, wherein mounting the anchor member comprises expanding the anchor member when it is in the stomach.