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Fabrication of a vascular system using sacrificial structures

  • US 9,242,027 B2
  • Filed: 07/16/2009
  • Issued: 01/26/2016
  • Est. Priority Date: 07/18/2008
  • Status: Active Grant
First Claim
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1. A method of producing a vascular network preform, said method comprising:

  • forming a network of elongate fibers randomly extending in a non-repeating pattern from a sacrificial material;

    forming at least one elongate structure from a sacrificial material, wherein the elongate structure has a diameter greater than that of the elongate fibers;

    placing the network of elongate fibers and the at least one elongate structure in contact with one another following or during said forming a network of elongate fibers or said forming at least one elongate structure;

    applying a matrix around the network of elongate fibers in contact with the at least one elongate structure; and

    sacrificing the network of elongate fibers and the at least one elongate structure within the matrix to form a preform containing a vascular network of fine diameter tubes in fluid communication with at least one elongate passage having a diameter greater than that of the fine diameter tubes.

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