Method for measuring hematocrit value of blood sample, method for measuring concentration of analyte in blood sample, sensor chip and sensor unit

• US 9,244,037 B2
• Filed: 03/18/2013
• Issued: 01/26/2016
• Est. Priority Date: 10/19/2006
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Inventors: Fujiwara, Masaki, Ikeda, Shin, Nakaminami, Takahiro
• Primary Examiner(s): DINH, BACH T
• Application Number:
  US13/845,907
• Publication Number:
  US 20140116879A1
• Time in Patent Office: 1,044 Days
• Field of Search: 20440301-40315, 2057775-778
• US Class Current: 1/1
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: G01N 27/413 Concentration cells using liquid electrolytes measuring currents or voltages in voltaic cells

Abstract

Provided is a sensor chip for electrochemically measuring a concentration of an analyte in a blood sample. In one embodiment of the sensor, the sensor chip includes a substrate, and a preliminary measurement analyzer and a hematocrit value analyzer disposed on the substrate. The preliminary measurement analyzer includes a preliminary working electrode and a preliminary counter electrode. The hematocrit value analyzer includes a working electrode and a counter electrode. An oxidant of a redox substance is disposed on the preliminary measurement analyzer and the counter electrode. A reductant of a redox substance is disposed on the working electrode.

Claims

1. A sensor chip for electrochemically measuring a concentration of an analyte in a blood sample, comprising:

a substrate,

a preliminary measurement analyzer and a hematocrit value analyzer disposed on the substrate,

the preliminary measurement analyzer comprising a preliminary working electrode and a preliminary counter electrode,

the hematocrit value analyzer comprising a working electrode and a counter electrode,

wherein a first reagent containing an oxidant of a redox substance is disposed to cover the surface of the preliminary measurement analyzer and the counter electrode,

a second reagent containing a reductant of a redox substance is disposed to cover the surface of the working electrode and

the first reagent and the second reagent are separated from each other on the substrate.

2. The sensor chip according to claim 1, wherein a common electrode is used for the preliminary working electrode and the counter electrode.

3. A sensor chip for electrochemically measuring a concentration of an analyte in a blood sample, comprising:

a substrate,

a preliminary measurement analyzer and a hematocrit value analyzer disposed on the substrate,

the preliminary measurement analyzer comprising a preliminary working electrode and a preliminary counter electrode,

the hematocrit value analyzer comprising a working electrode and a counter electrode,

wherein a first reagent containing an oxidant of a redox substance is disposed to cover the surface of the preliminary counter electrode and the counter electrode

a second reagent containing a reductant of a redox substance is disposed to cover the surface of the working electrode and

the first reagent and the second reagent are separated from each other on the substrate.

4. The sensor chip according to claim 3, wherein a common electrode is used for the preliminary working electrode and the counter electrode.