Received data processing apparatus of photoacoustic tomography

• US 9,247,923 B2
• Filed: 09/03/2009
• Issued: 02/02/2016
• Est. Priority Date: 09/04/2008
• Status: Active Grant

• Current Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Original Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Inventors: Baba, Yoshitaka, Yoda, Haruo, Fukutani, Kazuhiko
• Primary Examiner(s): Ratcliffe, Luke
• Assistant Examiner(s): Baghdasaryan, Hovhannes
• Application Number:
  US13/055,632
• Publication Number:
  US 20110128816A1
• Time in Patent Office: 2,343 Days
• Field of Search: 367/7, 367/8, 367/11, 367/135
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0073 by tomography, i.e. reconstruction of 3D images from 2D projections A61B5/0066 takes precedence
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 8/13 Tomography A61B8/10, A61B8/12 take precedence; tomography for radiation diagnosis A61B6/02
• CPC Class Codes: A61B 8/483 involving the acquisition of a 3D volume of data

Abstract

There is provided a received data processing apparatus of photoacoustic tomography including a minimum constitution unit data composition unit that sequentially reads receiving digital signals from first storage units and composes minimum constitution unit data of the acoustic wave of the minimum constitution units by performing a delay-and-sum processing. A second storage unit stores the minimum constitution unit data of the entire region of the specimen, and an image construction unit constructs an image of the specimen based on the minimum constitution unit data stored in the second storage unit. A control unit sequentially stores the minimum constitution unit data calculated by the minimum constitution unit data composition unit in the second storage unit and reads the stored minimum constitution unit data of the entire region of the specimen to transmit the minimum constitution unit data to the image construction unit.

Claims

1. A received data processing apparatus, comprising:

a plurality of conversion units that each perform digitization to digitize signals output from a plurality of acoustic wave detectors that receive acoustic waves generated in a specimen by absorption of light;

a plurality of first storage units each of which stores digital signals output from a respective one of said plurality of conversion units, only one of said first storage units receiving and storing digital signals from a given one of said conversion units;

a data composition unit that reads digital signals derived from the acoustic waves that originated from a target position in the specimen from said plurality of first storage units, reading from each of said first storage units the digital signal stored therein from said respective one of said conversion units, and adds digital signals read from said plurality of first storage units to compose data of the target position, and

an image construction unit that constructs an image based on the composed data of the target position,

wherein each of said plurality of first storage units stores at least the digital signals derived from acoustic waves generated by a single pulse of light, and

wherein said data composition unit composes photoacoustic tomography data of a plurality of target positions distributed in a three-dimensional region of the specimen by repetitively, for each pixel or voxel, reading digital signals for the single pulse of light stored in each of said plurality of first storage units, based on travel times that are required for acoustic waves from each of the plurality of target positions to reach the detectors.

2. The received data processing apparatus according to claim 1, wherein said plurality of first storage units store digital signals sequentially for each channel of plural channels that transmits a digital signal derived from the received acoustic waves.

3. The received data processing apparatus according to claim 1, further comprising:

a second storage unit that stores the data of the plurality of target positions in the specimen output from said data composition unit.

4. The received data processing apparatus according to claim 3, further comprising

a control unit that reads the data of the target position from said second storage unit and transmits the data of the target position to said image construction unit,

wherein said image construction unit constructs the image based on the data of the plurality of target positions stored in said second storage unit.

5. The received data processing apparatus according to claim 3,

further comprising a switching unit for connecting said plurality of first storage units and said data composition unit,

wherein said switching unit switches which one of said plurality of first storage units is connected to said data composition unit.

6. The received data processing apparatus according to claim 5, wherein said second storage unit comprises an addition unit that adds the data of the target positions which correspond to an identical target position and stores the added data.

7. The received data processing apparatus according to claim 1, wherein said data composition unit completes composition of the data of the plurality of target positions in a target region within the light-irradiation interval.

8. The received data processing apparatus according to claim 1, further comprising:

the plurality of acoustic wave detectors; and

a connection switch unit that switches at least one connection state from among connection states between said plurality of first storage units and said data composition unit, connection states between said plurality of conversion units and said plurality of first storage units, and connection states between said plurality of acoustic wave detectors and said plurality of conversion units.

9. The received data processing apparatus according to claim 1, wherein said second storage unit comprises an addition unit that adds the data of the target positions which correspond to an identical target position and stores the added data.

10. The received data processing apparatus according to claim 1, further comprising:

an address calculation unit that calculates delay times based on the travel times that are required for the acoustic wave from the target position to reach said acoustic wave detectors and supplies addresses where the digital signals derived from acoustic waves that originated from the target position are to be stored, corresponding to the delay times, to said plurality of first storage units.

11. The received data processing apparatus according to claim 1, further comprising:

a weighting factor calculation unit that calculates weight factors on respective channels which transmit the digital signals and applies the calculated weighting factors to said data composition unit.

12. The received data processing apparatus according to claim 1, further comprising:

a controller that changes a composition processing speed of the data of the target position by changing an operating frequency of a configuration subsequent to said conversion units.

13. The received data processing apparatus according to claim 1, wherein a plurality of said configurations subsequent to said conversion units are disposed in parallel.

14. The received data processing apparatus according to claim 1,

wherein said data composition unit composes photoacoustic tomography data of a plurality of target positions distributed in the three-dimensional region of the specimen by repetitively reading the digital signals for the single pulse of light stored in each of said plurality of first storage units, n times (where n is a natural number greater than 1), each time reading the digital signals stored in said first storage units, based on travel times that are required for acoustic waves from each of the plurality of target positions to reach said detectors, to compose data of a respective target position.

15. A photoacoustic apparatus, comprising:

a light source;

a plurality of acoustic wave detectors that convert acoustic waves generated in a specimen by absorption of light from said light source into received analog signals;

a plurality of conversion units, each converting one of the received analog signals into a received digital signal;

a plurality of first storage units that store the received digital signals output from said plurality of conversion units in time sequence; and

a data composition unit that reads the received digital signals, that originated from a target position from among a plurality of target positions in a target region of the specimen, from each of said plurality of first storage units based on travel times that are required for acoustic waves from the target positions to reach said plurality of acoustic detectors, and composes target position data which is data of the acoustic waves on each of the plurality of target positions; and

a second storage unit that stores the target position data of each of the plurality of target positions in the target region output from said data composition unit,

wherein each of said plurality of first storage units stores the received digital signals derived from the acoustic waves generated by a single pulse of light from said light source,

wherein said data composition unit composes the target position data of the plurality of the target positions in the target region by repetitively reading the received digital signals that are stored in said plurality of first storage units and are derived from the single pulse of light, and

wherein said second storage unit stores data calculated by adding a plurality of target position data which correspond to a same target position, the plurality of target position data being derived from acoustic waves received in different reception regions.

16. The photoacoustic apparatus according to claim 15, wherein said plurality of first storage units store digital signals sequentially for each channel of plural channels that transmits a digital signal derived from the received acoustic waves.

17. The photoacoustic apparatus according to claim 16, further comprising:

a weighting factor calculation unit that calculates weight factors on respective channels which transmit the digital signals and applies the calculated weighting factors to said data composition unit.

18. The photoacoustic apparatus according to claim 15, further comprising:

an image construction unit that constructs an image based on the data of the plurality of target positions stored in said second storage unit; and

a control unit that reads the data of the target position from said second storage unit and transmits the data of the target position to said image construction unit.

19. The photoacoustic apparatus according to claim 15, wherein said data composition unit composes the data of the plurality of target positions in the target region within a light-irradiation interval of said light source.

20. The photoacoustic apparatus according to claim 15,

further comprising a switching unit for connecting said plurality of first storage units and said data composition unit,

wherein said switching unit switches which one of said plurality of first storage units is connected to said data composition unit.

21. A data processing apparatus for processing data acquired by a plurality of acoustic wave detectors, the apparatus comprising:

a plurality of A/D converters each configured to digitize a signal output from a respective one of a plurality of acoustic wave detectors that receive an acoustic wave generated from a specimen by irradiation with a pulse of light at an irradiation time, a target region of the specimen being divided into a plurality of voxels arranged in three dimensions and delay times, taken from each voxel to the plurality of acoustic wave detectors, being calculated;

a plurality of storage units each configured to store the digitized signal acquired from a respective one of said plurality of A/D converters, a plurality of digitized signals, digitized by the plurality of A/D converters and corresponding to the acoustic wave generated from the specimen by irradiation with the pulse of light at the irradiation time, being stored by said plurality of storage units;

a data composition unit configured to compose voxel data of each voxel by reading the plurality of digitized signals, stored by said plurality of the storage units, to be summed based on the delay times, the stored digitized signals being repetitively read for composing a plurality of voxel data corresponding to the plurality of voxels arranged in three dimensions; and

an image construction unit that constructs an image based on the plurality of voxel data of the target region.

22. The data processing apparatus according to claim 21,

wherein the target region of the specimen is divided into the plurality of voxels arranged in three dimensions.

23. The data processing apparatus according to claim 21, wherein said data composition unit is configured to compose each voxel data of the voxels by using window function weighting factors.

24. The data processing apparatus according to claim 21, wherein said data composition unit is configured to complete composing all voxel data of the plurality of voxels before a next irradiation time after the irradiation time.

25. The data processing apparatus according to claim 21, wherein said data composition unit is configured to compose the entire voxel data of the plurality of voxels, corresponding to the acoustic wave generated from the specimen by irradiation with the pulse of light at the irradiation time, arranged in three dimensions.

26. The data processing apparatus according to claim 21, wherein said data composition unit is configured to compose each voxel data of the plurality of voxels by using other digitized signals corresponding to another acoustic wave generated from the specimen by irradiation with a pulse of light at another irradiation time.